Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rama Krishna Gurram"'
Autor:
Matthew J. Butcher, Rama Krishna Gurram, Xiaoliang Zhu, Xi Chen, Gangqing Hu, Vanja Lazarevic, Keji Zhao, Jinfang Zhu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
T-bet-expressing Th17 (T-bet+RORγt+) cells are associated with the induction of pathology during experimental autoimmune encephalomyelitis (EAE) and the encephalitic nature of these Th17 cells can be explained by their ability to produce GM-CSF. How
Externí odkaz:
https://doaj.org/article/8cd88d59ed244387b8829fc53ebf8205
Autor:
Weshely Kujur, Rama Krishna Gurram, Sudeep K. Maurya, Sajid Nadeem, Sathi Babu Chodisetti, Nargis Khan, Javed Naim Agrewala
Publikováno v:
Autoimmunity, Vol 50, Iss 5, Pp 317-328 (2017)
Multiple sclerosis (MS) is a highly detrimental autoimmune disease of the central nervous system. There is no cure for it but the treatment typically focuses on subsiding severity and recurrence of the disease. Experimental autoimmune encephalomyelit
Externí odkaz:
https://doaj.org/article/9126efc7a8d0449f8bea5bc43feb639b
Autor:
Arvind K Singla, Rama Krishna Gurram, Arun Chauhan, Neeraj Khatri, Rakesh M Vohra, Ravinder S Jolly, Javed N Agrewala
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e107051 (2014)
BACKGROUND: Caerulomycin A (CaeA) is a known antifungal and antibiotic agent. Further, CaeA is reported to induce the expansion of regulatory T cell and prolongs the survival of skin allografts in mouse model of transplantation. In the current study,
Externí odkaz:
https://doaj.org/article/72e4bf04c6c7412889758f079c076ede
Autor:
Zhishuo Wang, Chenghua Yan, Qizhen Du, Yuying Huang, Xuezhen Li, Dan Zeng, Ruizhi Mao, Rama Krishna Gurram, Shipeng Cheng, Wangpeng Gu, Lin Zhu, Weiguo Fan, Liyan Ma, Zhiyang Ling, Ju Qiu, Dangsheng Li, Enmei Liu, Yaguang Zhang, Yiru Fang, Jinfang Zhu, Bing Sun
Publikováno v:
Cellular & Molecular Immunology. 20:404-418
Autor:
Jinfang Zhu, Kairong Cui, Bing Sun, Andrew J. Oler, Ryoji Yagi, Difeng Fang, Pentao Liu, Suveena Sharma, Rama Krishna Gurram, Gangqing Hu, Ming Zhao, Keji Zhao, Chao Zhong
Publikováno v:
The Journal of Experimental Medicine
Bcl11b, a novel component of GATA3-containing transcriptional complex, inhibits Th2 cytokine production both in vitro and in vivo. Genome-wide analysis indicates that the Bcl11b/GATA3 complex not only limits the magnitude of Th2 response but also sup
Autor:
Rama Krishna Gurram, Sadiye Amcaoglu Rieder, Keji Zhao, Pan Su, Dragana Jankovic, Bing Sun, Gangqing Hu, Fang Yu, Suveena Sharma, Rao Li, Jinfang Zhu
Publikováno v:
The Journal of Experimental Medicine
The balance between inflammatory IFN-γ and antiinflammatory IL-10 plays a critical role in modulating type 1 immune responses. Yu et al. show that the transcription factor Bhlhe40 serves as a molecular switch between inflammatory and antiinflammator
Autor:
Rama Krishna Gurram, Jinfang Zhu
The type 2 immune response is critical for host defense against large parasites such as helminths. On the other hand, dysregulation of the type 2 immune response may cause immunopathological conditions, including asthma, atopic dermatitis, rhinitis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebeb5c6c3ef863c10380a2e513320b5
https://europepmc.org/articles/PMC6460501/
https://europepmc.org/articles/PMC6460501/
Publikováno v:
Journal of Biological Chemistry. 289:17515-17528
Cytokines play a very important role in the regulation of immune homeostasis. Regulatory T cells (Tregs) responsible for the generation of peripheral tolerance are under the tight regulation of the cytokine milieu. In this study, we report a novel ro
Autor:
Kammara Rajagopal, Kaneez F. Siddiqui, Mohammed Amir, Ashish Arora, Javed N. Agrewala, Rama Krishna Gurram, Nargis Khan
Publikováno v:
The Journal of Infectious Diseases. 209:1436-1445
Mycobacterium tuberculosis (M. tuberculosis) in latently infected individuals survives and thwarts the attempts of eradication by the immune system. During latency, Acr1 is predominantly expressed by the bacterium. However, whether M. tuberculosis ex
Autor:
Javed N. Agrewala, Kaneez F. Siddiqui, Weiguang Zeng, David C. Jackson, Uthaman Gowthaman, Pankaj Parihar, Sathi Babu Chodisetti, Vijender Singh, Shweta Jain, Umesh D. Gupta, Pushpa Gupta, Rama Krishna Gurram
Publikováno v:
The Journal of Infectious Diseases. 204:1328-1338
One of the main reasons considered for BCG failure in tuberculosis-endemic areas is impediment by environmental mycobacteria in its processing and generation of memory T-cell response. To overcome this problem, we developed a unique lipopeptide (L91)