Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rama K. Jaiswal"'
Publikováno v:
Journal of Biological Chemistry. 276:18169-18177
In PC12 cells, epidermal growth factor (EGF) transiently stimulates the mitogen-activated protein (MAP) kinases, ERK1 and ERK2, and provokes cellular proliferation. In contrast, nerve growth factor (NGF) stimulation leads to the sustained activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5560e41e442c35c27426da15b6cc6a2c
https://doi.org/10.1074/jbc.m008870200
https://doi.org/10.1074/jbc.m008870200
Publikováno v:
Molecular Medicine. 6:1028-1041
Tumor necrosis factor alpha (TNFα) plays a key role in pathogenesis of brain injury. However, TNFα exhibits no cytotoxicity in primary cultures of brain cells. This discrepancy suggests that other pathogenic stimuli that exist in the setting of bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bb252e28b934f4c1f33265f09181fa1
https://doi.org/10.1007/bf03402054
https://doi.org/10.1007/bf03402054
Autor:
Gabriel Mbalaviele, Rama K. Jaiswal, Mark F. Pittenger, Neelam Jaiswal, Daniel R. Marshak, Scott P. Bruder
Publikováno v:
Journal of Biological Chemistry. 275:9645-9652
Adult human mesenchymal stem cells are primary, multipotent cells capable of differentiating to osteocytic, chondrocytic, and adipocytic lineages when stimulated under appropriate conditions. To characterize the molecular mechanisms that regulate ost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54f6ce3b98f5cc3ae07801b0d6acadd
https://doi.org/10.1074/jbc.275.13.9645
https://doi.org/10.1074/jbc.275.13.9645
Publikováno v:
Molecular and Cellular Biology. 14:6944-6953
Nerve growth factor (NGF) activates the mitogen-activated protein (MAP) kinase cascade through a p21ras-dependent signal transduction pathway in PC12 cells. The linkage between p21ras and MEK1 was investigated to identify those elements which partici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f77069c4f5994439b4cad5aa37ce5165
https://doi.org/10.1128/mcb.14.10.6944
https://doi.org/10.1128/mcb.14.10.6944
Publikováno v:
Journal of Biological Chemistry. 268:7055-7063
Nerve growth factor treatment of PC12 cells results in the rapid activation of MAP kinases. These enzymes are activated through interaction with a protein "activator." The mitogen-activated protein (MAP) kinase activator has been partially purified b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b3ebceb2dcba9bbc5c7628e017fa331
https://doi.org/10.1016/s0021-9258(18)53144-6
https://doi.org/10.1016/s0021-9258(18)53144-6
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 22(2)
Preconditioning with sublethal ischemia results in natural tolerance to ischemic stress, where multiple mediators of ischemic damage are simultaneously counteracted. Tumor necrosis factor alpha (TNF-alpha) has been implicated in development of ischem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d558dbf71e6130e4159eb34eceb062
https://pubmed.ncbi.nlm.nih.gov/11823712
https://pubmed.ncbi.nlm.nih.gov/11823712
Autor:
Robin Douglas, Donald William Jr. Ward Road Simonetti, Stephen C. Beck, Stewart Craig, Daniel R. Marshak, Joseph D. Mosca, Mark Aaron Moorman, Mark F. Pittenger, Alastair Morgan Mackay, Rama K. Jaiswal
Publikováno v:
Science (New York, N.Y.). 284(5411)
Human mesenchymal stem cells are thought to be multipotent cells, which are present in adult marrow, that can replicate as undifferentiated cells and that have the potential to differentiate to lineages of mesenchymal tissues, including bone, cartila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c13ac354a921975f85691b53c084c047
https://pubmed.ncbi.nlm.nih.gov/10102814
https://pubmed.ncbi.nlm.nih.gov/10102814
Nerve growth factor (NGF) activates the mitogen-activated protein (MAP) kinase cascade through a p21ras-dependent signal transduction pathway in PC12 cells. The linkage between p21ras and MEK1 was investigated to identify those elements which partici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a770cc5103016a57cb0f15329ece2209
https://europepmc.org/articles/PMC359225/
https://europepmc.org/articles/PMC359225/
Autor:
Rama K. Jaiswal
Publikováno v:
Biochemical and biophysical research communications. 182(1)
Summary Preincubation of rat thoracic aortic smooth muscle cells with endothelin inhibits the atrial natriuretic factor (ANF)-induced cGMP accumulation in these cells in a concentration dependent manner. The maximal inhibition of 64% was afforded by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2010cc15a5e072e2b04474dec03024
https://pubmed.ncbi.nlm.nih.gov/1310017
https://pubmed.ncbi.nlm.nih.gov/1310017
Publikováno v:
Journal of Heterocyclic Chemistry. 16:561-565
A series of 5-(3,4,5-trimethoxyphenyl)-4-substituted aryl-3-hydrazinocarbonylmethylthio-4H-1,2,4-triazoles were synthesized and evaluated for their antiprotolytic and antiinflammatory activities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93e02cac35d8b95ebceb697ef403ccbf
https://doi.org/10.1002/jhet.5570160331
https://doi.org/10.1002/jhet.5570160331