Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rama Heng"'
Autor:
Cyrielle Andouche, Nathalie Membré, Morgane Reynaud, Célia Halter, André Zimmermann, Nicolas Basse, Renaud Morales, Louison Lebrun, Felix Bärenz, Arnaud Hohwald, Safia Deddouche-Grass, Fabienne Weber, Matthieu Poirot, Nicolas Muzet, Rama Heng, Véronique Roujean
Publikováno v:
ACS Medicinal Chemistry Letters. 12:1137-1142
ERAP1 is a key aminopeptidase involved in peptide trimming before major histocompatibility complex (MHC) presentation. A single nucleotide polymorphism (SNP) in the ERAP1 gene can lead to impaired trimming activity and affect ERAP1 function. ERAP1 ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9050b2c6c4df33995347377adbd6f2f0
https://doi.org/10.1021/acsmedchemlett.1c00235
https://doi.org/10.1021/acsmedchemlett.1c00235
Autor:
Safia, Deddouche-Grass, Cyrielle, Andouche, Felix, Bärenz, Célia, Halter, Arnaud, Hohwald, Louison, Lebrun, Nathalie, Membré, Renaud, Morales, Nicolas, Muzet, Matthieu, Poirot, Morgane, Reynaud, Véronique, Roujean, Fabienne, Weber, André, Zimmermann, Rama, Heng, Nicolas, Basse
Publikováno v:
ACS Med Chem Lett
[Image: see text] ERAP1 is a key aminopeptidase involved in peptide trimming before major histocompatibility complex (MHC) presentation. A single nucleotide polymorphism (SNP) in the ERAP1 gene can lead to impaired trimming activity and affect ERAP1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::615f3ab598a9fddc16f08cfadff81769
https://pubmed.ncbi.nlm.nih.gov/34267884
https://pubmed.ncbi.nlm.nih.gov/34267884
Autor:
Samir Z. Zard, Rama Heng
Publikováno v:
Tetrahedron Letters
Tetrahedron Letters, Elsevier, 2015, 56 (23), pp.3679-3682. ⟨10.1016/j.tetlet.2015.04.063⟩
Tetrahedron Letters, Elsevier, 2015, 56 (23), pp.3679-3682. ⟨10.1016/j.tetlet.2015.04.063⟩
International audience; Acetonyl radicals derived from TBS-protected 1-(alpha-xanthylacetyl)-1-cyclobutanes readily undergo addition to unactivated alkenes. Deprotection of the resulting adducts with Et4NF/THF and exposure to silica gel cause ring ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f56190e11773e2c90bb98365a11fefa
https://doi.org/10.1016/j.tetlet.2015.04.063
https://doi.org/10.1016/j.tetlet.2015.04.063
Publikováno v:
Tetrahedron Letters
Tetrahedron Letters, Elsevier, 2009, 50 (26), pp.3613-3616. ⟨10.1016/j.tetlet.2009.03.133⟩
Tetrahedron Letters, Elsevier, 2009, 50 (26), pp.3613-3616. ⟨10.1016/j.tetlet.2009.03.133⟩
International audience; The substitution reaction of chlorocyclobutanones with dithiocarbonates (xanthates) is greatly accelerated by the addition of a mild base such as DABCO or DBU. © 2009 Elsevier Ltd. All rights reserved.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b516f6b242dbb967914fb68c9839c2
https://doi.org/10.1016/j.tetlet.2009.03.133
https://doi.org/10.1016/j.tetlet.2009.03.133
Autor:
Samir Z. Zard, Rama Heng
Publikováno v:
ChemInform. 42
The transformation proceeds via a stabilized radical species involving the fragmentation of an unstrained carbon—carbon bond.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::592470dc6c69309b606e62691876ab2c
https://doi.org/10.1002/chin.201126031
https://doi.org/10.1002/chin.201126031
Autor:
Rama Heng, Samir Z. Zard
Publikováno v:
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2011, 9 (9), pp.3396-3404. ⟨10.1039/c1ob00024a⟩
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2011, 9 (9), pp.3396-3404. ⟨10.1039/c1ob00024a⟩
International audience; Cis- and trans-decalins, trans-perhydroazulenes, and [5.3.1]-bicyclo- undecanone scaffolds can be readily constructed starting from unsaturated ketones and using the degenerative xanthate transfer technology to accomplish unus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ae9e9610f3f7694dc802ae8e7091db
https://pubmed.ncbi.nlm.nih.gov/21423942
https://pubmed.ncbi.nlm.nih.gov/21423942
Publikováno v:
Organic Letters
Organic Letters, American Chemical Society, 2011, 13 (5), pp.1230-1233. ⟨10.1021/ol2001182⟩
Organic Letters, American Chemical Society, 2011, 13 (5), pp.1230-1233. ⟨10.1021/ol2001182⟩
International audience; Methylketone side chains can be used to direct the creation of one or more chiral centers, including quaternary centers, by exploiting the ability of the radical xanthate transfer process to mediate six-membered ring formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10968e0ac620136fd4f27cb27ce99930
https://hal-polytechnique.archives-ouvertes.fr/hal-00951235
https://hal-polytechnique.archives-ouvertes.fr/hal-00951235
Autor:
Samir Z. Zard, Rama Heng
Publikováno v:
Chemical Communications
Chemical Communications, Royal Society of Chemistry, 2011, 47 (11), pp.3296-3298. ⟨10.1039/c0cc04725b⟩
Chemical Communications, Royal Society of Chemistry, 2011, 47 (11), pp.3296-3298. ⟨10.1039/c0cc04725b⟩
International audience; An unusual radical fragmentation of an unstrained cyclohexane structure was observed leading to complex 1,2-diketones. © 2011 The Royal Society of Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2769172c70b58eecb03ac09811b8cc5
https://hal-polytechnique.archives-ouvertes.fr/hal-00950009
https://hal-polytechnique.archives-ouvertes.fr/hal-00950009
Publikováno v:
Organic Letters; Mar2011, Vol. 13 Issue 5, p1230-1233, 4p