Výsledky vyhledávání - "Ram S. Veerubhotla"

Potential of N-acetylated-para-aminosalicylic acid to accelerate manganese enhancement decline for long-term MEMRI in rodent brain

Autor: Ram S. Veerubhotla, Aditya N. Bade, JoEllyn M McMillan, Prabagaran Narayanasamy, Michael D. Boska, Howard E. Gendelman, Yutong Liu, Biyun Zhou

Publikováno v: Journal of Neuroscience Methods. 251:92-98

Background Manganese (Mn 2+ )-enhanced MRI (MEMRI) is a valuable imaging tool to study brain structure and function in normal and diseased small animals. The brain retention of Mn 2+ is relatively long with a half-life ( t 1/2 ) of 51–74 days causi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de934dc29d1c023a8d75708fa87a7b5
https://doi.org/10.1016/j.jneumeth.2015.05.013

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Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections

Autor: Ram S. Veerubhotla, Alexander V. Kabanov, Shantanu Balkundi, Xin Ming Liu, Howard E. Gendelman, Lindsey M. Kendrick, JoEllyn M McMillan, Tatiana K. Bronich, Pavan Puligujja, Nathan Smith, Benson J Edagwa, Tianyuzi Li

Publikováno v: Nanomedicine: Nanotechnology, Biology and Medicine. 9:1263-1273

Macrophages serve as vehicles for the carriage and delivery of polymer-coated nanoformulated antiretroviral therapy (nanoART). Although superior to native drug, high drug concentrations are required for viral inhibition. Herein, folate-modified riton

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52748a3376bd1fbe71b4c61fadc34af6
https://doi.org/10.1016/j.nano.2013.05.003

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Comparative manufacture and cell-based delivery of antiretroviral nanoformulations

Autor: Georgette D. Kanmogne, Tatiana K. Bronich, Alexander V. Kabanov, Xin Ming Liu, Ram S. Veerubhotla, Andrea Martinez-Skinner, Shantanu Balkundi, Han Chen, R. Lee Mosley, Upal Roy, JoEllyn M McMillan, Ari S. Nowacek, Howard E. Gendelman

Publikováno v: International Journal of Nanomedicine
Scopus-Elsevier
International Journal of Nanomedicine, Vol 2011, Iss default, Pp 3393-3404 (2011)

Shantanu Balkundi1, Ari S Nowacek1, Ram S Veerubhotla1, Han Chen2, Andrea Martinez-Skinner1, Upal Roy1, R Lee Mosley1,3, Georgette Kanmogne1, Xinming Liu1,3,4, Alexander V Kabanov3,4, Tatiana Bronich3,4, JoEllyn McMillan1, Howard E Gendelman1,31Depar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c8177d556ab1d254e99f7bdf299fa2
http://europepmc.org/articles/PMC3260033

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Functional proteome of macrophage carried nanoformulated antiretroviral therapy demonstrates enhanced particle carrying capacity

Autor: Han Liu, Huangui Xiong, Andrea Martinez-Skinner, Howard E. Gendelman, Fang Yu, JoEllyn M McMillan, Ram S. Veerubhotla

Publikováno v: Journal of proteome research. 12(5)

Our laboratory has pioneered the development of long-acting nanoformulations of antiretroviral therapy (nanoART). NanoART serves to improve drug compliance, toxicities, and access to viral reservoirs. These all function to improve treatment of human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3408bbf3c5812eb8eb024a0fd843770
https://pubmed.ncbi.nlm.nih.gov/23544708

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