Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ram Ramabhadran"'
Autor:
Naoto Hayasaka, Kazuyuki Aoki, Saori Kinoshita, Shoutaroh Yamaguchi, John K Wakefield, Sachiyo Tsuji-Kawahara, Kazumasa Horikawa, Hiroshi Ikegami, Shigeharu Wakana, Takamichi Murakami, Ram Ramabhadran, Masaaki Miyazawa, Shigenobu Shibata
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17655 (2011)
Regulators of G protein signaling (RGS) are a multi-functional protein family, which functions in part as GTPase-activating proteins (GAPs) of G protein α-subunits to terminate G protein signaling. Previous studies have demonstrated that the Rgs16 t
Externí odkaz:
https://doaj.org/article/0a6ba11143594b51b025d1b979eec38c
Autor:
Ram Ramabhadran
Publikováno v:
Modern Approaches in Drug Designing. 2
Publikováno v:
Nanotoxicology. 7:1064-1069
Zerovalent iron nanoparticles (nZVI) are used for in situ remediation of contaminated ground water, raising the possibility that nZVI particles or their altered residues could contaminate the ground water. Therefore, it is important to study their ef
Publikováno v:
Toxicology and Applied Pharmacology. 256:290-299
The vast literature on the mode of action of polychlorinated biphenyls (PCBs) indicates that PCBs are a unique model for understanding the mechanisms of toxicity of environmental mixtures of persistent chemicals. PCBs have been shown to adversely aff
Publikováno v:
Current Chemical Genomics
Exposure to metallic environmental toxicants has been demonstrated to induce a variety of oxidative stress responses in mammalian cells. The transcription factor Nrf2 is activated in response to oxidative stress and coordinates the expression of anti
Autor:
Seung-Hyun Cho, William P. Linak, Ram Ramabhadran, Robert Silbajoris, Tamara Tal, Lisa A. Dailey, Philip A. Bromberg, Steven O. Simmons, James M. Samet, William Reed
Publikováno v:
Toxicology and Applied Pharmacology. 243:46-54
Exposure to diesel exhaust particles (DEP) induces inflammatory signaling characterized by MAP kinase-mediated activation of NFkB and AP-1 in vitro and in bronchial biopsies obtained from human subjects exposed to DEP. NFkB and AP-1 activation result
Publikováno v:
Neurotoxicology and Teratology. 32:91-98
Hazard information essential to guide developmental neurotoxicity risk assessments is limited for many chemicals. As developmental neurotoxicity testing using rodents is laborious and expensive, alternative species such as zebrafish are being adapted
Autor:
Paul Greengard, Irina Dulubova, Li Shao, Gretchen L. Snyder, Ram Ramabhadran, Jean-Antoine Girault, Andrew J. Czernik, Angus C. Nairn, Atsuko Horiuchi
Publikováno v:
Journal of Neurochemistry. 77:229-238
Autor:
Laura Shaughnessy, Ayyappan Nair, Frank Koentgen, Beth Chamblin, Ram Ramabhadran, Mary Beth Thomas, John Wakefield
Publikováno v:
Current Alzheimer Research. 2:239-247
Lentiviral vectors are efficient tools for the introduction of genes into a wide range of established and primary cells in vitro, ex vivo, and in vivo, and also permit efficient transgenesis in a wide range of mammalian species. Our goals have been t
Autor:
Frank Koentgen, John Wakefield, Laura Shaughnessy, Beth Chamblin, Ayyappan Nair, Lori L. McMahon, Mary Beth Thomas, Ram Ramabhadran
Publikováno v:
Journal of Molecular Neuroscience. 24:023-032
Development of therapeutics for Alzheimer's disease (AD) requires appropriate cell culture models that reflect the errant biochemical pathways and animal models that reflect the pathological hallmarks of the disease as well as the clinical manifestat