Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ram P. Vanam"'
Publikováno v:
mAbs, Vol 11, Iss 7, Pp 1319-1330 (2019)
Biotherapeutic proteins are commonly dosed at high concentrations into the blood, which is an inherently complex, crowded solution with substantial protein content. The effects of macromolecular crowding may lead to an appreciable level of non-specif
Externí odkaz:
https://doaj.org/article/ebaeebd8830d4c89a466b109c218b558
An alternative method to traditional 2-dimensional gel electrophoresis (2D-PAGE) and its application in characterizing the inherent charge heterogeneity of chromatographically isolated monoclonal antibody heavy and light chains is described. This met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881c2be1c41508584bde88a1f78d0c2b
https://europepmc.org/articles/PMC4966340/
https://europepmc.org/articles/PMC4966340/
Publikováno v:
Biomacromolecules. 9(9)
The aggregation of insulin near its isoelectric point and at low ionic strength was suppressed in the presence of heparin. To understand this effect, we used turbidimetry and stopped-flow to study the pH- and ionic strength ( I)-dependence of the agg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ad63cf704c1bfe4404cb2b43473f52
https://pubmed.ncbi.nlm.nih.gov/18698815
https://pubmed.ncbi.nlm.nih.gov/18698815