Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ram N. Trivedi"'
Autor:
Robert W. Sobol, Ashley R. Brown, David Svilar, Elena Jelezcova, Claudette M. St Croix, Ram N. Trivedi, Xiao-hong Wang, Eva M. Goellner, Jiang-bo Tang
Base excision repair (BER) protein expression is important for resistance to DNA damage–induced cytotoxicity. Conversely, BER imbalance [DNA polymerase β (Polβ) deficiency or repair inhibition] enhances cytotoxicity of radiation and chemotherapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7291a9fb8906b99625f969ff9406a0
https://doi.org/10.1158/1541-7786.c.6541945.v1
https://doi.org/10.1158/1541-7786.c.6541945.v1
Autor:
Robert W. Sobol, Ashley R. Brown, David Svilar, Elena Jelezcova, Claudette M. St Croix, Ram N. Trivedi, Xiao-hong Wang, Eva M. Goellner, Jiang-bo Tang
Supplementary Data from Bioenergetic Metabolites Regulate Base Excision Repair–Dependent Cell Death in Response to DNA Damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f28120e37456dba5965c4c9bed0377c
https://doi.org/10.1158/1541-7786.22518490.v1
https://doi.org/10.1158/1541-7786.22518490.v1
Autor:
Robert W. Sobol, Jiang-bo Tang, Ram N. Trivedi, Leah Mitchell, Kelsey F. Sugrue, Xiao-Hong Wang, Ying-Chih Lin, Ashley R. Brown, Bradford Grimme, Eva M. Goellner
Glioblastoma multiforme (GBM) is a devastating brain tumor with poor prognosis and low median survival time. Standard treatment includes radiation and chemotherapy with the DNA alkylating agent temozolomide (TMZ). However, a large percentage of tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64e44da0e46c7b13db68b335141cd672
https://doi.org/10.1158/0008-5472.c.6503126.v1
https://doi.org/10.1158/0008-5472.c.6503126.v1
DNA-alkylating agents have a central role in the curative therapy of many human tumors; yet, resistance to these agents limits their effectiveness. The efficacy of the alkylating agent temozolomide has been attributed to the induction of O6-MeG, a DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989b5a2c797f7d25fe4ec41166a94380
https://doi.org/10.1158/0008-5472.c.6494384.v1
https://doi.org/10.1158/0008-5472.c.6494384.v1
Supplementary Information from The Role of Base Excision Repair in the Sensitivity and Resistance to Temozolomide-Mediated Cell Death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499ca27e268d40ea47fb93e720c6b146
https://doi.org/10.1158/0008-5472.22364831.v1
https://doi.org/10.1158/0008-5472.22364831.v1
Supplementary Figure S4 from The Role of Base Excision Repair in the Sensitivity and Resistance to Temozolomide-Mediated Cell Death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b578bc7a8ee4e2f8e7d9e7639b3d66
https://doi.org/10.1158/0008-5472.22364834.v1
https://doi.org/10.1158/0008-5472.22364834.v1
Autor:
Robert W. Sobol, Jiang-bo Tang, Ram N. Trivedi, Leah Mitchell, Kelsey F. Sugrue, Xiao-Hong Wang, Ying-Chih Lin, Ashley R. Brown, Bradford Grimme, Eva M. Goellner
Supplementary Methods, Figures 1-6, Table 1 from Overcoming Temozolomide Resistance in Glioblastoma via Dual Inhibition of NAD+ Biosynthesis and Base Excision Repair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6178cbcb02e7884cc2cd0dff6640ebed
https://doi.org/10.1158/0008-5472.22391033
https://doi.org/10.1158/0008-5472.22391033
Autor:
Cristiane de Oliveira, Krutika Patel, Vivek Mishra, Ram N Trivedi, Pawan Noel, Abhilasha Singh, Jordan R Yaron, Vijay P Singh
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149073 (2016)
BACKGROUND:Studying the uptake of 2-deoxy glucose (2-DG) analogs such as 2-Deoxy-2-[18F] fluoroglucose (FDG) is a common approach to identify and monitor malignancies and more recently chronic inflammation. While pancreatitis is a common cause for fa
Externí odkaz:
https://doaj.org/article/cf7d74bcac1e46d2a2a4f73b4241a390
Autor:
Ram N. Trivedi, Pawan Noel, Krutika Patel, Cristiane de Oliveira, Vijay P. Singh, Chandra Durgampudi
Publikováno v:
The American Journal of Pathology. 186:874-884
Although ethanol causes acute pancreatitis (AP) and lipolytic fatty acid (FA) generation worsens AP, the contribution of ethanol metabolites of FAs, ie, FA ethyl esters (FAEEs), to AP outcomes is unclear. Previously, pancreata of dying alcoholics and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c2f2fd7c5632301b0ba2be605c9c70
https://doi.org/10.1016/j.ajpath.2015.11.022
https://doi.org/10.1016/j.ajpath.2015.11.022
Autor:
Sonya Narla, Vivek Mishra, Krutika Patel, Chandra Durgampudi, Chathur Acharya, Pawan Noel, Vijay P. Singh, John A. Holmes, Ram N. Trivedi
Publikováno v:
Pancreatology. 14:459-464
Background and objectives Multiple deleterious signaling cascades are simultaneously activated in acute pancreatitis (AP), which may limit the success of pharmacologic approaches targeting a single step. We explored whether cooling acinar cells slows
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864ad5597f9e072506c7c6061ef9c08a
https://doi.org/10.1016/j.pan.2014.06.006
https://doi.org/10.1016/j.pan.2014.06.006