Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ram K C Venigalla"'
Autor:
Ram K C Venigalla, Victoria A. McGuire, Laste Stojanovski, Rosemary G. Clarke, Rachel Toth, Janet C. Patterson-Kane, J. Simon C. Arthur, Ayaz Najafov, Frederick R. C. Simeons, Pierre C McCarthy
Publikováno v:
The EMBO Journal
Phosphoinositide-dependent kinase-1 (PDK1) controls the activation of a subset of AGC kinases. Using a conditional knockout of PDK1 in haematopoietic cells, we demonstrate that PDK1 is essential for B cell development. B-cell progenitors lacking PDK1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6fcd185d0b5786a6f98ae17371551d
https://doi.org/10.1038/emboj.2013.40
https://doi.org/10.1038/emboj.2013.40
Autor:
Morisada, Hayakawa, Hiroko, Hayakawa, Tsvetana, Petrova, Patcharee, Ritprajak, Ruhcha V, Sutavani, Guillermina Yanek, Jiménez-Andrade, Yasuyo, Sano, Min-Kyung, Choo, John, Seavitt, Ram K C, Venigalla, Kinya, Otsu, Katia, Georgopoulos, J Simon C, Arthur, Jin Mo, Park
Publikováno v:
The Journal of Biological Chemistry
The evolutionarily conserved protein kinase p38 mediates innate resistance to environmental stress and microbial infection. Four p38 isoforms exist in mammals and may have been co-opted for new roles in adaptive immunity. Murine T cells deficient in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95d9860764cbd76c20e0a68128a28509
https://pubmed.ncbi.nlm.nih.gov/28011639
https://pubmed.ncbi.nlm.nih.gov/28011639
Autor:
Rachel Toth, Janet C. Patterson-Kane, Alban Ordureau, David W. Powell, Philip Cohen, Sambit K. Nanda, Ram K C Venigalla, J. Simon C. Arthur
Publikováno v:
The Journal of Experimental Medicine
The polyubiquitin-binding domain of ABIN1 limits TLR-induced MyD88 signaling to prevent spontaneous autoimmunity in mice.
The protein ABIN1 possesses a polyubiquitin-binding domain homologous to that present in nuclear factor κB (NF-κB) essent
The protein ABIN1 possesses a polyubiquitin-binding domain homologous to that present in nuclear factor κB (NF-κB) essent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb9c0cf434398901d735dae2eb497da
https://doi.org/10.1084/jem.20102177
https://doi.org/10.1084/jem.20102177
Autor:
Nele, Gao, Julia, Dresel, Volker, Eckstein, Rimma, Gellert, Hannah, Störch, Ram K C, Venigalla, Vedat, Schwenger, Regina, Max, Norbert, Blank, Hanns-Martin, Lorenz, Theresa, Tretter
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 66(10)
B cells with immunoregulatory properties (Breg cells) have been described in mice, but their role in the control of human immune responses is not well defined. We recently identified a human population of activated FSC(high) B cells that exhibited re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f17d204cc3ffc9785a9ebba728bb2cc
https://pubmed.ncbi.nlm.nih.gov/24942956
https://pubmed.ncbi.nlm.nih.gov/24942956
Autor:
Martin R Turner, Ram K. C. Venigalla
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
Frontiers in Immunology
Frontiers in Immunology
Understanding the mechanisms by which signal transduction pathways mediate changes in RNA abundance requires the examination of the fate of RNA from its transcription to its degradation. Evidence suggests that RNA abundance is partly regulated by pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af45c6150233ff1081940c5f75206a63