Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ramón Trullas"'
Autor:
Raquel Carrasco, Mercedes Ingelmo-Torres, Ramón Trullas, Fiorella L. Roldán, Leonardo Rodríguez-Carunchio, Lourdes Juez, Joan Sureda, Antonio Alcaraz, Lourdes Mengual, Laura Izquierdo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16578 (2023)
Circulating tumor DNA (ctDNA) has recently emerged as a real-time prognostic and predictive biomarker for monitoring cancer patients. Here, we aimed to ascertain whether tumor-agnostic ctDNA testing would be a feasible strategy to monitor disease pro
Externí odkaz:
https://doaj.org/article/def7f30238f642a4a4e34a04d46a818d
Autor:
Raquel Carrasco, Mercedes Ingelmo-Torres, Ascensión Gómez, Ramón Trullas, Fiorella L. Roldán, Tarek Ajami, Davinia Moreno, Leonardo Rodríguez-Carunchio, Antonio Alcaraz, Laura Izquierdo, Lourdes Mengual
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11732 (2022)
Cell-free DNA (cfDNA) has recently emerged as a real-time biomarker for diagnosis, monitoring and prediction of therapy response in tumoral disease. Here, we evaluated cfDNA as a prognostic biomarker for monitoring muscle-invasive bladder cancer (MIB
Externí odkaz:
https://doaj.org/article/df2a775388d54fefa75702403166f484
Autor:
Aloa Lamarca, Alejandro Gella, Tania Martiañez, Mònica Segura, Joana Figueiro-Silva, Carmen Grijota-Martinez, Ramón Trullas, Núria Casals
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98998 (2014)
In response to peripheral nerve injury, Schwann cells adopt a migratory phenotype and modify the extracellular matrix to make it permissive for cell migration and axonal re-growth. Uridine 5'-triphosphate (UTP) and other nucleotides are released duri
Externí odkaz:
https://doaj.org/article/6bd0ca95eafb47019cf1c1d48946d645
Autor:
Lourdes Mengual, Raquel Carrasco, Mercedes Ingelmo-Torres, Ascensión Gómez, Ramón Trullas, Fiorella L. Roldán, Tarek Ajami, Joan Sureda, Sandra Herranz, Antonio Alcaraz, Laura Izquierdo
Publikováno v:
Journal of Urology. 209
Autor:
Margalida Puigròs, Anna Calderon, Daniel Martín-Ruiz, Mònica Serradell, Manel Fernández, Amaia Muñoz-Lopetegi, Gerard Mayà, Joan Santamaria, Carles Gaig, Anna Colell, Eduard Tolosa, Alex Iranzo, Ramon Trullas
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105065- (2024)
Summary: Background: Idiopathic rapid eye movement (REM) sleep behaviour disorder (IRBD) represents the prodromal stage of Lewy body disorders (Parkinson's disease (PD) and dementia with Lewy bodies (DLB)) which are linked to variations in circulatin
Externí odkaz:
https://doaj.org/article/ffffee7d37fc4a8c8da4cca684795f85
Autor:
Verónica Pablo-Fontecha, Eva Hernández-Illán, Andrea Reparaz, Elena Asensio, Jordi Morata, Raúl Tonda, Sara Lahoz, Carolina Parra, Juan José Lozano, Anabel García-Heredia, Alejandro Martínez-Roca, Sergi Beltran, Francesc Balaguer, Rodrigo Jover, Antoni Castells, Ramon Trullàs, Petar Podlesniy, Jordi Camps
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Somatic single-nucleotide variants (SNVs) occur every time a cell divides, appearing even in healthy tissues at low frequencies. These mutations may accumulate as neutral variants during aging, or eventually, promote the development of neopl
Externí odkaz:
https://doaj.org/article/99864895717e491da635fbdea8589d17
Autor:
Cristina de Dios, Xenia Abadin, Vicente Roca-Agujetas, Marina Jimenez-Martinez, Albert Morales, Ramon Trullas, Montserrat Mari, Anna Colell
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-23 (2023)
Abstract Background Persistent inflammatory response in the brain can lead to tissue damage and neurodegeneration. In Alzheimer's disease (AD), there is an aberrant activation of inflammasomes, molecular platforms that drive inflammation through casp
Externí odkaz:
https://doaj.org/article/d67c08fc39e14f8ea51fdd4ce91c409e
Autor:
Irene Serra, Julio Esparza, Laura Delgado, Cristina Martín-Monteagudo, Margalida Puigròs, Petar Podlesniy, Ramón Trullás, Marta Navarrete
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Neuron-astrocyte communication is fundamental for brain physiology, yet the heterogeneity in the functional interaction between these two elements remains poorly understood. Here we show how different neuron-astrocyte networks integrate information f
Externí odkaz:
https://doaj.org/article/059fc93c4a3e4d1897b8b9f761b952e5
Autor:
Mireia Ortega, Ilario De Toma, Álvaro Fernández-Blanco, Anna Calderón, Lucía Barahona, Ramón Trullàs, Eduard Sabidó, Mara Dierssen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
IntroductionDYRK1A is a dual-specificity kinase that is overexpressed in Down syndrome (DS) and plays a key role in neurogenesis, neuronal differentiation and function, cognitive phenotypes, and aging. Dyrk1A has also been implicated in cerebellar ab
Externí odkaz:
https://doaj.org/article/a94a519789dc467983ae50dd54cb6dfd
Autor:
Margalida Puigròs, Anna Calderon, Alexandra Pérez-Soriano, Cristina de Dios, Manel Fernández, Anna Colell, Maria-José Martí, Eduardo Tolosa, Ramon Trullas
Publikováno v:
Neurobiology of Disease, Vol 174, Iss , Pp 105885- (2022)
Mitochondrial dysfunction happens in both idiopathic (iPD) and LRRK2-related Parkinson's disease (LRRK2-PD). Nonetheless, previous studies suggested that a different type of mitochondrial pathology underlies the neurodegeneration in these two disorde
Externí odkaz:
https://doaj.org/article/ea2fbd6ab56e40a598e7f2f092c6d23e