Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Ramón Martínez Pacheco"'
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 45, Iss 4, Pp 669-675 (2009)
The aim of this study was to develop granules from Phyllanthus niruri spray-dried extract using dry and wet granulation and to assess techniques to enable the production of granules with improved technological characteristics and yields. Granules wer
Externí odkaz:
https://doaj.org/article/03631a137bbf4870b4220ca300d8a680
Publikováno v:
Gaceta Sanitaria, Vol 25, Iss 4, Pp 342-343 (2011)
Externí odkaz:
https://doaj.org/article/53517330b29b45f1b3db676e29b3dace
Publikováno v:
Gaceta Sanitaria, Vol 26, Iss 2, Pp 194-194 (2012)
Externí odkaz:
https://doaj.org/article/886e09c294d44ed58b5cf4cc52927abd
Autor:
Angel Concheiro, Carmen Alvarez-Lorenzo, Ramón Martínez-Pacheco, José Luis Gómez-Amoza, Livia C. Sa-Barreto
Publikováno v:
Journal of Drug Delivery Science and Technology. 42:292-298
Matrix pellets of acetaminophen were prepared by extrusion-spheronization using a high proportion of several varieties of Eudragit; namely, 40% RSPO or RLPO, and 17% RS30D or RL30D. The pellets were characterized using textural analysis of gray-level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d166981718e27aac67bbe98f955cd16
https://doi.org/10.1016/j.jddst.2017.04.027
https://doi.org/10.1016/j.jddst.2017.04.027
Autor:
Jhonny Azuaje, Elena Raviña-Eirín, Ramón Martínez-Pacheco, Eddy Sotelo, José Luis Gómez-Amoza
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 102:1-8
The aim of this study was firstly to evaluate the utility of Hybrane S1200 as a hot melt extrusion (HME) carrier to prepare instant-release multiparticulate systems for very poorly-soluble drugs such as ketoconazole or nifedipine. Hybrane S1200 allow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada8622ca0380f15c39a877eef4a66da
https://doi.org/10.1016/j.ejpb.2016.02.008
https://doi.org/10.1016/j.ejpb.2016.02.008
Autor:
Jie Wang, Alvaro Goyanes, Abdul Basit, Ramón Martínez-Pacheco, Simon Gaisford, Richard Telford, Asma B. M. Buanz
Publikováno v:
Molecular Pharmaceutics. 12:4077-4084
Three dimensional printing (3D printing) was used to fabricate novel oral drug delivery devices with specialized design configurations. Each device was loaded with multiple actives, with the intent of applying this process to the production of person
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505418e48c6848b40b6cfae2900c1f0e
https://doi.org/10.1021/acs.molpharmaceut.5b00510
https://doi.org/10.1021/acs.molpharmaceut.5b00510
Publikováno v:
Drug Development and Industrial Pharmacy. 41:1000-1005
The objective of this study is to evaluate the dissolution of a poorly soluble drug (prednisolone) from different sized matricial particles (from250 to1500 µm) with two drug contents (10% or 20%) obtained by hot melt extrusion using the hyperbranche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a61e181da89661fe20785773a6db501d
https://doi.org/10.3109/03639045.2014.922572
https://doi.org/10.3109/03639045.2014.922572
Publikováno v:
Journal of Pharmacy and Pharmacology. 65:798-806
Objectives In this work, the effects of several technological factors on the stability of β-lapachone (βLAP) in solution and in the solid state were investigated. Methods The effects of relative humidity and light on the stability of βLAP in the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88fb01c17b1f685b516b02dffea4a309
https://doi.org/10.1111/jphp.12040
https://doi.org/10.1111/jphp.12040
Publikováno v:
International journal of pharmaceutics. 514(1)
Fused deposition modeling (FDM) 3–Dimensional (3D) printing is becoming an increasingly important technology in the pharmaceutical sciences, since it allows the manufacture of personalized oral dosage forms by deposition of thin layers of material.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ca47b8789455a928cd26366981449f
https://pubmed.ncbi.nlm.nih.gov/27863674
https://pubmed.ncbi.nlm.nih.gov/27863674
Publikováno v:
Drug Development and Industrial Pharmacy. 39:1107-1112
Particles composed of 90:10 or 80:20 mixtures of the hyperbranched poly(esteramide) Hybrane S1200 and the poorly water-soluble drug hydrochlorothiazide were produced by hot melt extrusion at maximum temperatures of 90°C without any need for addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c2ecb165923f78cecba63f765e7f92
https://doi.org/10.3109/03639045.2012.713363
https://doi.org/10.3109/03639045.2012.713363