Výsledky vyhledávání - "Raluca Mihaescu"

Akademický článek

Tricyclic antidepressants for major depressive disorder: a comprehensive evaluation of current practice in the Netherlands

Autor: Cornelis F. Vos, Rob E. Aarnoutse, Marijke J. M. Op de Coul, Jan Spijker, Mascha M. Groothedde-Kuyvenhoven, Raluca Mihaescu, Sonja J. W. Wessels-Basten, Jordy J. E. Rovers, Sophie E. ter Hark, Aart H. Schene, Marlies E. J. L. Hulscher, Joost G. E. Janzing

Publikováno v: BMC Psychiatry, Vol 21, Iss 1, Pp 1-11 (2021)

Abstract Background Traditionally tricyclic antidepressants (TCAs) have an important place in treatment of major depressive disorder (MDD). Today, often other antidepressant medications are considered as first step in the pharmacological treatment of

Externí odkaz: https://doaj.org/article/dc824c69f1c94f3ea0a85bae6f79c62a

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Tricyclic antidepressants for major depressive disorder: A comprehensive evaluation of current practice in the Netherlands

Autor: Sophie E. ter Hark, Jordy J. E. Rovers, Aart H. Schene, Marlies E J L Hulscher, Joost G. E. Janzing, Jan Spijker, Raluca Mihaescu, Marijke J. M. Op de Coul, Cornelis F. Vos, Sonja J. W. Wessels-Basten, Mascha M. Groothedde-Kuyvenhoven, Rob E. Aarnoutse

Publikováno v: BMC Psychiatry, 21
BMC Psychiatry
BMC Psychiatry, Vol 21, Iss 1, Pp 1-11 (2021)

Background Traditionally tricyclic antidepressants (TCAs) have an important place in treatment of major depressive disorder (MDD). Today, often other antidepressant medications are considered as first step in the pharmacological treatment of MDD, mai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a844a179da06bb5d4eec4fdd30e503
https://repository.ubn.ru.nl/handle/2066/237531

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Mild cognitive impairment and risk of depression and anxiety: A population-based study

Autor: Raluca Mihaescu, M. Arfan Ikram, Albert Hofman, Daniel Bos, Henning Tiemeier, Saira Saeed Mirza

Publikováno v: Alzheimers & Dementia, 13(2), 130-139. Elsevier Inc.

Introduction Many people with mild cognitive impairment (MCI) suffer from concomitant depression or anxiety. Whether MCI increases the risk of future depression or anxiety is unknown. Methods In the Rotterdam Study, cross-sectional (n = 4168) and lon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949f310d5188fb4f6051cc5d7633dd67
https://doi.org/10.1016/j.jalz.2016.06.2361

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Variations in predicted risks in personal genome testing for common complex diseases

Autor: Raluca Mihaescu, Robert C. Green, A. Cecile J.W. Janssens, Suman Kundu, Rachel R.J. Kalf, Peter de Knijff

Publikováno v: Genetics in Medicine, 16(1), 85-91. Lippincott Williams & Wilkins
Genetics in Medicine, 16(1), 85-91

Purpose: The promise of personalized genomics for common complex diseases depends, in part, on the ability to predict genetic risks on the basis of single nucleotide polymorphisms. We examined and compared the methods of three companies (23andMe, deC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa87e3f88669043577ca0d38ab57b21
https://doi.org/10.1038/gim.2013.80

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A Methodological Perspective on Genetic Risk Prediction Studies in Type 2 Diabetes: Recommendations for Future Research

Autor: Raluca Mihaescu, A. Cecile J.W. Janssens, Sara M. Willems, Cornelia M. van Duijn, Eric J.G. Sijbrands

Publikováno v: Current Diabetes Reports
Current Diabetes Reports, 11(6), 511-518. Current Medicine Group

Fueled by the successes of genome-wide association studies, numerous studies have investigated the predictive ability of genetic risk models in type 2 diabetes. In this paper, we review these studies from a methodological perspective, focusing on the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fcdfcdec8ae5c343b39c25d5ea954c9
http://europepmc.org/articles/PMC3207129

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Translational Research in Genomics of Alzheimer's Disease: A Review of Current Practice and Future Perspectives

Autor: A. Cecile J.W. Janssens, Wiesje M. van der Flier, Raluca Mihaescu, Symone B. Detmar, Martina C. Cornel, Marcel G. M. Olde Rikkert, Peter Heutink, Cornelia M. van Duijn, Elly M. Hol

Publikováno v: Journal of Alzheimer's Disease, 20(4), 967-980. IOS Press
Journal of Alzheimer's Disease, 20, 4, pp. 967-80
Journal of Alzheimer's Disease, 20, 967-980. IOS Press
Journal of Alzheimer's Disease, 20, 967-80
Mihaescu, R, Detmar, S B, Cornel, M C, van der Flier, W M, Heutink, P, Hol, E M, Rikkert, M G M O, van Duijn, C M & Janssens, A C J W 2010, ' Translational Research in Genomics of Alzheimer's Disease: A Review of Current Practice and Future Perspectives ', Journal of Alzheimer's Disease, vol. 20, no. 4, pp. 967-980 . https://doi.org/10.3233/JAD-2010-1410
Journal of Alzheimer's Disease, 4, 20, 967-980
Journal of Alzheimers Disease, 20(4), 967-980. IOS Press BV

Contains fulltext : 87613.pdf (Publisher’s version ) (Open Access) Alzheimer's disease (AD) is the most prevalent form of dementia and the number of cases is expected to increase exponentially worldwide. Three highly penetrant genes (AbetaPP, PSEN1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7580429f4d9384abb81feaebcb76b8
https://doi.org/10.3233/jad-2010-1410

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Improvement of Risk Prediction by Genomic Profiling: Reclassification Measures Versus the Area Under the Receiver Operating Characteristic Curve

Autor: A. Cecile J.W. Janssens, Albert Hofman, M. G. Myriam Hunink, André G. Uitterlinden, Cornelia M. van Duijn, Eric J.G. Sijbrands, Mandy van Hoek, Raluca Mihaescu, Moniek van Zitteren, Jacqueline C. M. Witteman

Publikováno v: American Journal of Epidemiology, 172(3), 353-361. Oxford University Press

Reclassification is observed even when there is no or minimal improvement in the area under the receiver operating characteristic curve (AUC), and it is unclear whether it indicates improved clinical utility. The authors investigated total reclassifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f08072817684cc47056bc8616417c7
https://doi.org/10.1093/aje/kwq122

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Estimating the predictive ability of genetic risk models in simulated data based on published results from genome-wide association studies

Autor: Suman Kundu, A. Cecile J.W. Janssens, Raluca Mihaescu, Rachel Bakker, Catherina M. C. Meijer

Publikováno v: Frontiers in Genetics, Vol 5 (2014)
Frontiers in Genetics, 5:179. Frontiers Media S.A.
Frontiers in Genetics

Background: There is increasing interest in investigating genetic risk models in empirical studies, but such studies are premature when the expected predictive ability of the risk model is low. We assessed how accurately the predictive ability of gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5471975f1ef3b6b290c833011a7939e9

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Scientific reporting is suboptimal for aspects that characterize genetic risk prediction studies: a review of published articles based on the Genetic RIsk Prediction Studies statement

Autor: Raluca Mihaescu, Adriana I. Iglesias, Cornelia M. van Duijn, Julian Little, John P. A. Ioannidis, Muin J. Khoury, A. Cecile J.W. Janssens

Publikováno v: Journal of Clinical Epidemiology, 67(5), 487-499. Elsevier Inc.

Objectives: Our main objective was to raise awareness of the areas that need improvements in the reporting of genetic risk prediction articles for future publications, based on the Genetic Risk Prediction Studies (GRIPS) statement. Study Design and S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587253ec23d4b9fa8838e16840791a18
https://pure.eur.nl/en/publications/75af6c47-8e0c-4826-90a7-f48ba961bbe7

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