Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Raluca A Niesner"'
Autor:
Carolin Ulbricht, Ruth Leben, Asylkhan Rakhymzhan, Frank Kirchhoff, Lars Nitschke, Helena Radbruch, Raluca A Niesner, Anja E Hauser
Publikováno v:
eLife, Vol 10 (2021)
Calcium is a universal second messenger present in all eukaryotic cells. The mobilization and storage of Ca2+ ions drives a number of signaling-related processes, stress–responses, or metabolic changes, all of which are relevant for the development
Externí odkaz:
https://doaj.org/article/23cb8f32d40044f082c0f1a13df9a9ce
Autor:
Till Fabian Mertens, Alina Tabea Liebheit, Johanna Ehl, Ralf Köhler, Asylkhan Rakhymzhan, Andrew Woehler, Lukas Katthän, Gernot Ebel, Wjatscheslaw Liublin, Ana Kasapi, Antigoni Triantafyllopoulou, Tim Julius Schulz, Raluca Aura Niesner, Anja Erika Hauser
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Analyzing immune cell interactions in the bone marrow is vital for understanding hematopoiesis and bone homeostasis. Three-dimensional analysis of the complete, intact bone marrow within the cortex of whole long bones remains a challenge, es
Externí odkaz:
https://doaj.org/article/ce98ba8479a34113a4359a3ee8fa5a81
Autor:
Ronja Mothes, Anna Pascual-Reguant, Ralf Koehler, Juliane Liebeskind, Alina Liebheit, Sandy Bauherr, Lars Philipsen, Carsten Dittmayer, Michael Laue, Regina von Manitius, Sefer Elezkurtaj, Pawel Durek, Frederik Heinrich, Gitta A. Heinz, Gabriela M. Guerra, Benedikt Obermayer, Jenny Meinhardt, Jana Ihlow, Josefine Radke, Frank L. Heppner, Philipp Enghard, Helena Stockmann, Tom Aschman, Julia Schneider, Victor M. Corman, Leif E. Sander, Mir-Farzin Mashreghi, Thomas Conrad, Andreas C. Hocke, Raluca A. Niesner, Helena Radbruch, Anja E. Hauser
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Infection with SARS-CoV-2 has been linked with substantive inflammation, lung pathology and development of COVID-19. Here the authors spatially associate CCL18 and CCL21 in distinct tissue niches with lung pathology of severe COVID-19.
Externí odkaz:
https://doaj.org/article/1b2247b6d5234d329b89d09ddd2a8d84
In good times and in bad: How plasma cells resolve stress for a life-long union with the bone marrow
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/b88e8205a2804ac29db831331159d8c9
Autor:
Wjatscheslaw Liublin, Sebastian Rausch, Ruth Leben, Randall L. Lindquist, Alexander Fiedler, Juliane Liebeskind, Ingeborg E. Beckers, Anja E. Hauser, Susanne Hartmann, Raluca A. Niesner
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Infections with intestinal nematodes have an equivocal impact: they represent a burden for human health and animal husbandry, but, at the same time, may ameliorate auto-immune diseases due to the immunomodulatory effect of the parasites. Thu
Externí odkaz:
https://doaj.org/article/8e52b3b3e61a47e59b7d4c641fbe7def
Autor:
Lennard Ostendorf, Philipp Dittert, Robert Biesen, Ankelien Duchow, Victoria Stiglbauer, Klemens Ruprecht, Judith Bellmann-Strobl, Dominik Seelow, Werner Stenzel, Raluca A. Niesner, Anja E. Hauser, Friedemann Paul, Helena Radbruch
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract We aimed to evaluate SIGLEC1 (CD169) as a biomarker in multiple sclerosis (MS) and Neuromyelitis optica spectrum disorder (NMOSD) and to evaluate the presence of SIGLEC1+ myeloid cells in demyelinating diseases. We performed flow cytometry-b
Externí odkaz:
https://doaj.org/article/9dbd84d824d44f7f9ebb0bb35db75826
Autor:
David Reismann, Jonathan Stefanowski, Robert Günther, Asylkhan Rakhymzhan, Romano Matthys, Reto Nützi, Sandra Zehentmeier, Katharina Schmidt-Bleek, Georg Petkau, Hyun-Dong Chang, Sandra Naundorf, York Winter, Fritz Melchers, Georg Duda, Anja E. Hauser, Raluca A. Niesner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Longitudinal imaging of bone marrow would shed insight into long-term cellular dynamics within this compartment. Here, the authors develop a multi-photon imaging approach for the mouse femur and reveal extensive vascular plasticity within the bone ma
Externí odkaz:
https://doaj.org/article/5461e2efd91248698ccbbea37bccb7fc
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 6046 (2021)
Two-photon microscopy enables monitoring cellular dynamics and communication in complex systems, within a genuine environment, such as living tissues and, even, living organisms. Particularly, its application to understand cellular interactions in th
Externí odkaz:
https://doaj.org/article/5d049c66536c4c73be654627e08dbb1e
Autor:
Asylkhan Rakhymzhan, Ruth Leben, Hanna Zimmermann, Robert Günther, Peggy Mex, David Reismann, Carolin Ulbricht, Andreas Acs, Alexander U. Brandt, Randall L. Lindquist, Thomas H. Winkler, Anja E. Hauser, Raluca A. Niesner
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Simultaneous detection of multiple cellular and molecular players in their native environment, one of the keys to a full understanding of immune processes, remains challenging for in vivo microscopy. Here, we present a synergistic strategy f
Externí odkaz:
https://doaj.org/article/b33b7358951648f988bec043ea650aa8
Autor:
Lennard Ostendorf, Ronja Mothes, Sofie van Koppen, Randall L. Lindquist, Judith Bellmann-Strobl, Susanna Asseyer, Klemens Ruprecht, Tobias Alexander, Raluca A. Niesner, Anja E. Hauser, Friedemann Paul, Helena Radbruch
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Objective: To investigate whether low-density granulocytes (LDGs) are an immunophenotypic feature of patients with multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD).Methods: Blood samples were collected from 20 patients with N
Externí odkaz:
https://doaj.org/article/e7b47ab309d342608715b7d429248454