Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ralph Yamamoto"'
Publikováno v:
Blood. 110:3928-3928
Low Molecular Weight Heparins are carbohydrate-based therapeutics with anticoagulant activities. Common brands include: Lovenox, Fragmin and Arixtra, which are currently used to treat Deep Vein Thromobosis. Unlike protein or peptide-based drugs, easy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c81a5d31a919b81dd4e1ad04e6c49ceb
https://doi.org/10.1182/blood.v110.11.3928.3928
https://doi.org/10.1182/blood.v110.11.3928.3928
Publikováno v:
Proceedings of the National Academy of Sciences. 81:5662-5666
Human fibroblast interferon has three cysteine residues, located at amino acid positions 17, 31, and 141. Using the technique of site-specific mutagenesis with a synthetic oligonucleotide primer, we changed the codon for cysteine-17 to a codon for se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb3c7c63e9d42cf950f75313a80a893
https://doi.org/10.1073/pnas.81.18.5662
https://doi.org/10.1073/pnas.81.18.5662
Publikováno v:
Proceedings of the National Academy of Sciences. 84:3293-3297
We compared the molecular structure of the receptor to human recombinant tumor necrosis factor (HurTNF) on cells of different tissue origin that differ in their response to one of the known activities of TNF. We studied tumor cell lines that respond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe424d59a7dcc6216142c89f44a32eb7
https://doi.org/10.1073/pnas.84.10.3293
https://doi.org/10.1073/pnas.84.10.3293
Autor:
Charles R. Vitt, Ralph Yamamoto, Brian M. Fendly, Karen J. Toy, Abla A. Creasey, Leo Lin, James W. Larrick
Publikováno v:
Hybridoma. 6:359-370
A panel of four monoclonal antibodies (MAbs) was generated against recombinant human tumor necrosis factor-alpha (rTNF). These MAbs immunoprecipitate 125I-labeled rTNF, block binding of 125I-labeled rTNF to L929 mouse fibroblasts, and neutralize in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97dca8600e46d326683e5da556718ec
https://doi.org/10.1089/hyb.1987.6.359
https://doi.org/10.1089/hyb.1987.6.359
Publikováno v:
Protein engineering. 2(7)
The amino acids that are required for the cytotoxic activity of recombinant human tumor necrosis factor-alpha (TNF) were investigated by chemical modification and oligonucleotide-directed site-specific mutagenesis. TNF contains three histidine residu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ade18ff675b4fad3c9b937562915f4f6
https://pubmed.ncbi.nlm.nih.gov/2546145
https://pubmed.ncbi.nlm.nih.gov/2546145
Publisher Summary This chapter discusses the purification of recombinant human interferon β (IFN-β) expressed in Escherichia coli . Many purification methods developed for native (glycosylated) human IFN-β are not applicable to nonglycosylated rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::999c040af4207808acd75fd678bef62d
https://doi.org/10.1016/0076-6879(86)19028-8
https://doi.org/10.1016/0076-6879(86)19028-8
Autor:
Charles R. Vitt, Kirk W. Johnson, Mary Beth Giacona, Bob Goodson, Anton F. Ehrhardt, Simon Ng, Jill Winter, John M. Nuss, Ralph Yamamoto, Marty Giedlin, Walter H. Moos, Anke Krebber, Martha B. Ladner
Publikováno v:
Scopus-Elsevier
Peptoids differ from peptides in that peptoids are composed of N-substituted rather than alpha-carbon-substituted glycine units. In this paper we report the in vitro and in vivo antibacterial activities of several antibacterial peptoids discovered by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210dec18aaf2d9f8b7346b988d896914
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033027897&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033027897&partnerID=MN8TOARS