Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ralph Tammariello"'
Autor:
Gary John Dstl Phillips, Martha L. Hale, Leonard A. Smith, Luis DaSilva, Ralph Tammariello, Rebecca Erwin-Cohen, Aimee Porter
Publikováno v:
Toxicon. 58:68-75
To protect against ricin intoxication, a genetically derived ricin A chain vaccine candidate (RVEc) was developed lacking the toxic N-glycosidase activity (Olson et al., 2004). The vaccine protects animals against an aerosolized ricin holotoxin (RT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0c1375e62cf2308fcce9d1029e3bd1
https://doi.org/10.1016/j.toxicon.2011.05.005
https://doi.org/10.1016/j.toxicon.2011.05.005
Autor:
Leonard A. Smith, Rowena D Schokman, Changhong Y. Lindsey, Ralph Tammariello, John H. Carra, Richard E. Dinterman, Robert W. Wannemacher
Publikováno v:
Vaccine. 25:4149-4158
Ricin is a potent toxin associated with bioterrorism for which no vaccine or specific countermeasures are currently available. A stable, non-toxic and immunogenic recombinant ricin A-chain vaccine (RTA 1-33/44-198) has been developed by protein engin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13bab6de2a9d90600719503038d8f338
https://doi.org/10.1016/j.vaccine.2007.03.011
https://doi.org/10.1016/j.vaccine.2007.03.011
Publikováno v:
Vaccine. 20:1681-1691
Mucosal (oral) immunization of mice with carrier-delivered ricin toxoid (RT) vaccine was accomplished by one long (7 weeks) or two short (4 weeks) immunization schedules. For the long and short immunization schedule two lots of vaccine were administe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35de9e7c6355c5d10534a9ae09e12b25
https://doi.org/10.1016/s0264-410x(01)00484-4
https://doi.org/10.1016/s0264-410x(01)00484-4
Autor:
Alan L. Schmaljohn, Lorna Vanderzanden, Michael Hevey, Jonathan F. Smith, Connie S. Schmaljohn, Diane L. Negley, Ralph Tammariello, Peter B. Jahrling, Joan B. Geisbert
Publikováno v:
Vaccine. 20:586-593
An effort to develop a safe and effective vaccine for Marburg virus (MBGV), one of the filoviruses known to cause high mortality rates in humans, led us to compare directly some of the merits of modern versus classical vaccine approaches for this age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32f1940dc5848d66b8d860902430e9b
https://doi.org/10.1016/s0264-410x(01)00353-x
https://doi.org/10.1016/s0264-410x(01)00353-x
Autor:
William D. Pratt, Russell R. Bakken, Mary Kate Hart, Keith E. Steele, K. Caswell-Stephan, Robert E. Johnston, Nancy L. Davis, Ralph Tammariello, Jonathan F. Smith
Publikováno v:
Vaccine. 18:3067-3075
The genetically engineered, live-attenuated Venezuelan equine encephalitis (VEE) virus vaccine candidate, V3526, was evaluated as a replacement for the TC-83 virus vaccine. Protection from lethal subcutaneous or aerosol challenge was evaluated in vac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a5eec007698a5e0942c8000eae0857
https://doi.org/10.1016/s0264-410x(00)00042-6
https://doi.org/10.1016/s0264-410x(00)00042-6
Publikováno v:
Vaccine. 15:363-369
Immunization with either a live-attenuated (TC-83) or formalin-inactivated (C-84) vaccine for Venezuelan equine encephalitis (VEE) virus protected BALB/c mice from lethal VEE infection acquired subcutaneously or by aerosol. While vaccinated C3H/HeN m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2752d3d604608ccbde4ad1b0f476d3fb
https://doi.org/10.1016/s0264-410x(96)00204-6
https://doi.org/10.1016/s0264-410x(96)00204-6
Autor:
Changhong Yan, Hina Naseem, Ralph Tammariello, Robert Malli, John Hewetson, Meir Kende, Wayne L. Rill
Publikováno v:
Vaccine. 14:1031-1038
Intranasal (i.n.) immunization with ricin toxoid (RT) vaccine encapsulated in poly (lactide-co-glycolide) microspheres (RT-PLG-Ms) and poly (L-lactide) microspheres (RT-PLA-Ms) stimulated systemic and mucosal immune responses and protected mice from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad63f653128180cf9455da0e1150ba4b
https://doi.org/10.1016/0264-410x(96)00063-1
https://doi.org/10.1016/0264-410x(96)00063-1
Publikováno v:
Vaccine. 13:645-651
Biodegradable microparticles made of poly(lactide-co-glycolide) (PLG) were used for protracted and pulsed-release of the incorporated ricin toxoid (RT) vaccine to reduce the multiple immunization doses and the time required to induce complete protect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68455af0b59d273c794202496c373aa6
https://doi.org/10.1016/0264-410x(94)00026-j
https://doi.org/10.1016/0264-410x(94)00026-j
Autor:
Bret K. Purcell, Leonard A. Smith, Robert G. Ulrich, Patricia L. Worsham, Jason B. Alarcon, John A. Mikszta, Garry L. Morefield, Jennifer Chapman, Ralph Tammariello
Publikováno v:
Journal of Immune Based Therapies and Vaccines
Background Combination vaccines reduce the total number of injections required for each component administered separately and generally provide the same level of disease protection. Yet, physical, chemical, and biological interactions between vaccine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f59704c7814168bfef1a70a2193282
https://doi.org/10.1186/1476-8518-6-5
https://doi.org/10.1186/1476-8518-6-5
Publikováno v:
Protein science : a publication of the Protein Society. 13(10)
Ricin is a potent toxin presenting a threat as a biological weapon. The holotoxin consists of two disulfide-linked polypeptides: an enzymatically active A chain (RTA) and a galactose/N-acetylgalactosamine-binding B chain. Efforts to develop an inacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebaefa28b78ef4262dd77850e093049
https://pubmed.ncbi.nlm.nih.gov/15340172
https://pubmed.ncbi.nlm.nih.gov/15340172