Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Ralph S Marcucio"'
Autor:
Jose D Aponte, David C Katz, Daniela M Roth, Marta Vidal-García, Wei Liu, Fernando Andrade, Charles C Roseman, Steven A Murray, James Cheverud, Daniel Graf, Ralph S Marcucio, Benedikt Hallgrímsson
Publikováno v:
eLife, Vol 10 (2021)
Realistic mappings of genes to morphology are inherently multivariate on both sides of the equation. The importance of coordinated gene effects on morphological phenotypes is clear from the intertwining of gene actions in signaling pathways, gene reg
Externí odkaz:
https://doaj.org/article/88b99fdbe9bf4745aa04504d6544da97
Autor:
David C Katz, J David Aponte, Wei Liu, Rebecca M Green, Jessica M Mayeux, K Michael Pollard, Daniel Pomp, Steven C Munger, Stephen A Murray, Charles C Roseman, Christopher J Percival, James Cheverud, Ralph S Marcucio, Benedikt Hallgrímsson
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233377 (2020)
The biology of how faces are built and come to differ from one another is complex. Discovering normal variants that contribute to differences in facial morphology is one key to untangling this complexity, with important implications for medicine and
Externí odkaz:
https://doaj.org/article/6a6a871e7a96439fbe99f3557fe52694
Publikováno v:
Frontiers in Endocrinology, Vol 6 (2015)
Fracture healing is critically dependent upon an adequate vascular supply. The normal rate for fracture delayed or non-union is estimated to be between 10-15%, and annual fracture numbers are approximately 15 million cases per year. However, when the
Externí odkaz:
https://doaj.org/article/efc6e5d5060049168b736e02beb08443
Publikováno v:
PLoS Genetics, Vol 10, Iss 11, p e1004724 (2014)
Externí odkaz:
https://doaj.org/article/ae5e73db88204f27ac64ced818a685a1
Autor:
Danielle J Behonick, Zhiqing Xing, Shirley Lieu, Jenni M Buckley, Jeffrey C Lotz, Ralph S Marcucio, Zena Werb, Theodore Miclau, Céline Colnot
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1150 (2007)
Extracellular matrix (ECM) remodeling is important during bone development and repair. Because matrix metalloproteinase 13 (MMP13, collagenase-3) plays a role in long bone development, we have examined its role during adult skeletal repair. In this s
Externí odkaz:
https://doaj.org/article/1f84ec6326834e2e943c5a9110a0b3b3
Autor:
Kevin O. Rivera, Darnell L. Cuylear, Victoria R. Duke, Kelsey M. O’Hara, Justin X. Zhong, Nafisa A. Elghazali, Joel A. Finbloom, Bhushan N. Kharbikar, Alex N. Kryger, Theodore Miclau, Ralph S. Marcucio, Chelsea S. Bahney, Tejal A. Desai
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: Currently, there are no non-surgical FDA-approved biological approaches to accelerate fracture repair. Injectable therapies designed to stimulate bone healing represent an exciting alternative to surgically implanted biologics, however,
Externí odkaz:
https://doaj.org/article/2d67733dedb841e4b0796fa4acfa384e
Autor:
Jay Devine, Marta Vidal-García, Wei Liu, Amanda Neves, Lucas D. Lo Vercio, Rebecca M. Green, Heather A. Richbourg, Marta Marchini, Colton M. Unger, Audrey C. Nickle, Bethany Radford, Nathan M. Young, Paula N. Gonzalez, Robert E. Schuler, Alejandro Bugacov, Campbell Rolian, Christopher J. Percival, Trevor Williams, Lee Niswander, Anne L. Calof, Arthur D. Lander, Axel Visel, Frank R. Jirik, James M. Cheverud, Ophir D. Klein, Ramon Y. Birnbaum, Amy E. Merrill, Rebecca R. Ackermann, Daniel Graf, Myriam Hemberger, Wendy Dean, Nils D. Forkert, Stephen A. Murray, Henrik Westerberg, Ralph S. Marcucio, Benedikt Hallgrímsson
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-18 (2022)
Abstract Complex morphological traits are the product of many genes with transient or lasting developmental effects that interact in anatomical context. Mouse models are a key resource for disentangling such effects, because they offer myriad tools f
Externí odkaz:
https://doaj.org/article/7defe75069d24f29bca1c5a94da00059
Autor:
Jay Devine, Marta Vidal-García, Wei Liu, Amanda Neves, Lucas D. Lo Vercio, Rebecca M. Green, Heather A. Richbourg, Marta Marchini, Colton M. Unger, Audrey C. Nickle, Bethany Radford, Nathan M. Young, Paula N. Gonzalez, Robert E. Schuler, Alejandro Bugacov, Campbell Rolian, Christopher J. Percival, Trevor Williams, Lee Niswander, Anne L. Calof, Arthur D. Lander, Axel Visel, Frank R. Jirik, James M. Cheverud, Ophir D. Klein, Ramon Y. Birnbaum, Amy E. Merrill, Rebecca R. Ackermann, Daniel Graf, Myriam Hemberger, Wendy Dean, Nils D. Forkert, Stephen A. Murray, Henrik Westerberg, Ralph S. Marcucio, Benedikt Hallgrímsson
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/be08db417e494e3e9e3dd747d51524cb
Autor:
Rebecca M. Green, Lucas D. Lo Vercio, Andreas Dauter, Elizabeth C. Barretto, Jay Devine, Marta Vidal-García, Marta Marchini, Samuel Robertson, Xiang Zhao, Anandita Mahika, M. Bilal Shakir, Sienna Guo, Julia C. Boughner, Wendy Dean, Arthur D. Lander, Ralph S. Marcucio, Nils D. Forkert, Benedikt Hallgrímsson
Morphogenesis requires highly coordinated, complex interactions between cellular processes: proliferation, migration, and apoptosis, along with physical tissue interactions. How these cellular and tissue dynamics drive morphogenesis remains elusive.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::853481149004152883b2952e43a4dcb1
https://doi.org/10.1101/2023.05.12.540515
https://doi.org/10.1101/2023.05.12.540515
Autor:
Nathaniel Zbasnik, Katie Dolan, Stephanie A. Buczkowski, Rebecca M. Green, Benedikt Hallgrímsson, Ralph S. Marcucio, Anne M. Moon, Jennifer L. Fish
Publikováno v:
Developmental Dynamics. 251:1711-1727
Asymmetries in craniofacial anomalies are commonly observed. In the facial skeleton, the left side is more commonly and/or severely affected than the right. Such asymmetries complicate treatment options. Mechanisms underlying variation in disease sev