Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ralph Remus"'
Publikováno v:
Cellular Physiology and Biochemistry, Vol 34, Iss 2, Pp 346-355 (2014)
Background: Impairment of regulatory T cells (Tregs) in common autoimmune diseases seems likely. However, the extent of Treg deficiency (number, function) or differential susceptibility of T effector cells (Teffs) to suppression is not completely und
Externí odkaz:
https://doaj.org/article/a0d1ceb3bf9842da8ef5f8f3e1316ca4
Publikováno v:
Cellular Physiology and Biochemistry, Vol 34, Iss 2, Pp 346-355 (2014)
Background: Impairment of regulatory T cells (Tregs) in common autoimmune diseases seems likely. However, the extent of Treg deficiency (number, function) or differential susceptibility of T effector cells (Teffs) to suppression is not completely und
Autor:
Frauke Naumann, Michael Zeschnigk, Ines Zuther, Hideho Wada, Walter Doerfler, Birgit Schmitz, Yoshihito Yawata, Hidekazu Nakanishi, Ayumi Yawata, Ralph Remus, Akio Kanzaki, Takashi Sugihara
Publikováno v:
International Journal of Hematology. 82:422-429
Red cell membrane proteins are sequentially expressed during erythroid development and differentiation. Spectrins have already been synthesized in early erythroid precursors such as pronormoblasts, and band 3 (B3) appears at nearly the same stage. Pr
Autor:
Michael Zeschnigk, Walter Doerfler, HidehoAkio Wada, Ralph Remus, Birgit Schmitz, Akio Kanzaki, Ines Zuther, Yoshihito Yawata, Ayumi Yawata, Gudrun Schell, Indrikis Muiznieks
Publikováno v:
Gene Function & Disease. 2:171-184
The state of methylation of the 5′-CpG-3′ sites is known to be linked to the regulation of promoter function by modulating DNA-protein interactions and to the structure of chromatin. As part of a project to determine methylation patterns in the h
Autor:
Norman Putzki, Dietmar Knop, Ernst Kreuzfelder, Manoj Kumar, Monika Lindemann, Ralph Remus, Norbert Mueller, Volker Limmroth, Hans Grosse-Wilde, Cornelia Hardt
Publikováno v:
Journal of neuroimmunology. 180(1-2)
Multiple sclerosis (MS) is an autoimmune disorder directed against self antigens of the central nervous system. CD4(+)CD25(+)FoxP3(+) regulatory T cell (T(reg)) mediated suppression is an essential mechanism of self-tolerance. We studied whether chan
Publikováno v:
Genomics. 83(1)
The human nuclear 5'-(CGG)(n)-3'-binding protein (CGGBP1) influences the expression of the fragile X mental retardation (FMR1) gene by specifically interacting with the 5'-(CGG)(n5)-3' repeat in its 5' untranslated region. Here, we show that CGGBP1 b
Autor:
Birgit Schmitz, Andreas Dorn, Marianna Hösel, Reinhold Buettner, Lars Corzilius, Ralph Remus, Anke Niemann, Kristina Hilger-Eversheim, Anja Schramme, Dennis Webb, Walter Doerfler, Urte Hohlweg
Publikováno v:
Virus research. 98(1)
The intramuscular (i.m.) injection of human adenovirus type 12 (Ad12) into newborn Syrian hamsters caused widespread dissemination of up to 15 tumors over the entire peritoneal cavity in 70–90% of the animals within 30–50 days. Subcutaneous (s.c.
Publikováno v:
Annals of the New York Academy of Sciences. 945
We have been interested in the consequences of foreign DNA insertion into established mammalian genomes and have initially studied this problem in adenovirus type 12 (Ad12)-transformed cells or in Ad12-induced hamster tumors. Since integrates are fre
The insertion of adenovirus type 12 (Ad12) DNA into the hamster genome and the transformation of these cells by Ad12 can lead to marked alterations in the levels of DNA methylation in several cellular genes and DNA segments. Since such alterations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13885c5833f013ef1208eef3814e94d9
https://europepmc.org/articles/PMC103921/
https://europepmc.org/articles/PMC103921/
Autor:
Ralph Remus, Walter Doerfler, Christina Kämmer, Hilde Heller, Kristina Hilger-Eversheim, M. Knoblauch, Rainer Schubbert
Publikováno v:
Trends in biotechnology. 15(8)
The insertion of foreign DNA into the genomes of established cells and organisms and the consequences of this integration event are of significance for viral oncology, reverse genetics, transgenic organisms, human somatic gene therapy and evolution.