Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ralph Meuwissen"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/a9dec78785dd4d59ad12a55db153e469
Autor:
Ralph Meuwissen, S. De Seranno
Publikováno v:
European Respiratory Journal. 35:426-443
The continued progress of modelling lung cancer in mice has led not only to new means of understanding the molecular pathways governing human lung cancer, but it has also created a vast reservoir of alternative tools to test treatments against this m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62889c47f95d4809fb982d8a194e4c6
https://doi.org/10.1183/09031936.00124709
https://doi.org/10.1183/09031936.00124709
Autor:
Roghaiyeh, Safari, Ralph, Meuwissen
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1267
To date a variety of non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) mouse models have been developed that mimic human lung cancer. Chemically induced or spontaneous lung cancer in susceptible inbred strains has been widely used,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::468a818ad3bc7bd76173938db7595c3a
https://pubmed.ncbi.nlm.nih.gov/25636466
https://pubmed.ncbi.nlm.nih.gov/25636466
Autor:
Roghaiyeh Safari, Ralph Meuwissen
Publikováno v:
Methods in Molecular Biology ISBN: 9781493922963
To date a variety of non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) mouse models have been developed that mimic human lung cancer. Chemically induced or spontaneous lung cancer in susceptible inbred strains has been widely used,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::197c5cb928604b9bddae6868264f6b31
https://doi.org/10.1007/978-1-4939-2297-0_5
https://doi.org/10.1007/978-1-4939-2297-0_5
Autor:
Theo van Laar, Evert van Garderen, Daniel S. Peeper, John Zevenhoven, Ralph Meuwissen, Sirith Douma
Publikováno v:
Nature, 430(7003), 1034-1040. Nature Publishing Group
Metastasis is a major factor in the malignancy of cancers, and is often responsible for the failure of cancer treatment. Anoikis (apoptosis resulting from loss of cell-matrix interactions) has been suggested to act as a physiological barrier to metas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd35ca6e4ec3f23be4919a6bc8bd9ae7
https://hdl.handle.net/11370/ce245719-b577-4c18-b74c-6f89d1bc967d
https://hdl.handle.net/11370/ce245719-b577-4c18-b74c-6f89d1bc967d
Autor:
Anton Berns, John Zevenhoven, Wolter J. Mooi, R. Ilona Linnoila, Ralph Meuwissen, Sabine C. Linn
Publikováno v:
Cancer Cell. 4(3):181-189
Small cell lung cancer (SCLC) is a highly aggressive human tumor with a more than 95% mortality rate. Its ontogeny and molecular pathogenesis remains poorly understood. We established a mouse model for neuroendocrine (NE) lung tumors by conditional i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7411a8f920e71fbc509c7b2e8f712dcf
Publikováno v:
Experimental Cell Research. 264:100-110
Much of the advancement in mouse models for cancer during the past 2 decades can be attributed to our increasing capacity to specifically modify the mouse germ line. The first generations of oncomice and tumor-suppressor gene knockouts are now being
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11928149e32ca102f7e3ea35d67a6f6
https://doi.org/10.1006/excr.2000.5146
https://doi.org/10.1006/excr.2000.5146
Autor:
François Cuzin, Christa Heyting, Julien Sage, Minoo Rassoulzadegan, Ralph Meuwissen, Luc Martin
Publikováno v:
Mechanisms of development 80 (1999) 1
Mechanisms of development, 80(1), 29-39
Mechanisms of development, 80(1), 29-39
Transcription controls active at the initial stages of meiosis are clearly key elements in the regulation of germinal differentiation. Transcription of the Sycp1 gene (synaptonemal complex protein 1) starts as early as the leptotene and zygotene stag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aface01f1fd1dad61fb17291e17de0f
https://doi.org/10.1016/s0925-4773(98)00191-9
https://doi.org/10.1016/s0925-4773(98)00191-9
Publikováno v:
miRNomics: MicroRNA Biology and Computational Analysis ISBN: 9781627037471
About 20 years have passed since the discovery of the first microRNA (miRNA) and by now microRNAs are implicated in a variety of physiological and pathological processes. Since the discovery of the powerful effect miRNAs have on biological processes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c89b2ebc47b94d6feea917d53b2e163
https://doi.org/10.1007/978-1-62703-748-8_3
https://doi.org/10.1007/978-1-62703-748-8_3
Publikováno v:
miRNomics: MicroRNA Biology and Computational Analysis ISBN: 9781627037471
MicroRNAs (miRNAs) are tiny regulators of gene expression on the posttranscriptional level. Since the discovery of the first miRNA 20 years ago, thousands of them have been described. The discovered miRNAs have regulatory functions in biological and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::094314df78e0124e658467673817d442
https://doi.org/10.1007/978-1-62703-748-8_2
https://doi.org/10.1007/978-1-62703-748-8_2