Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ralph M. Böhmer"'
Autor:
Simone Reinwald, James Dromey, Esther Bandala-Sanchez, Yuxia Zhang, Leonard C. Harrison, Bo-Han Lee, Ralph M. Böhmer, Junyan Qian
Publikováno v:
Nature Immunology. 14:741-748
Functionally diverse T cell populations interact to maintain homeostasis of the immune system. We found that human and mouse antigen-activated T cells with high expression of the lymphocyte surface marker CD52 suppressed other T cells. CD52(hi)CD4(+)
Autor:
Gaetano Naselli, Priscilla Auyeung, Grant Morahan, Yuxia Zhang, Julian J. Bosco, Maryam Rashidi, Leonard C. Harrison, Alana M. Neale, Esther Bandala-Sanchez, John M. Wentworth, Ralph M. Böhmer, Natalie L. Stone, Petra Augstein
Publikováno v:
Current diabetes reports. 13(5)
Insulin-dependent or type 1 diabetes (T1D) is a paradigm for prevention of autoimmune disease: Pancreatic β-cell autoantigens are defined, at-risk individuals can be identified before the onset of symptoms, and autoimmune diabetes is preventable in
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 79(8)
Following activation by antigen, T cells enter the cell cycle in stages that can be defined with flow cytometric markers. We show that these markers include the increase of forward light scatter width (FSC-W) signal and the ratio of FSC area/peak. Th
Autor:
Ralph M. Böhmer
Publikováno v:
Journal of Cellular Physiology. 155:79-88
Cell density negative control (CDNC) of normal human fibroblast proliferation occurs after stimulation by mitogens with different signal transduction mechanism. Delayed exposure to agents that interfere with CDNC, such as doublestranded RNA and vanad
Autor:
Ralph M. Böhmer
Publikováno v:
Journal of Cellular Physiology. 146:191-196
When quiescent normal skin fibroblasts are stimulated by mitogens such as epidermal growth factor (EGF), the proportion of cells entering a division cycle decreases with increasing cell density. The presence of a synthetic double-stranded RNA (poly I
Autor:
Ralph M. Böhmer
Publikováno v:
Growth factors (Chur, Switzerland). 22(1)
We have shown previously that erythropoiesis in cultures from fetal blood depends less on interleukin-3 (IL3) than erythropoiesis from adult blood. This paper explores if this is due to different proportions of stem cell sub-populations with differen
Autor:
Ralph M. Böhmer
Publikováno v:
Stem cells (Dayton, Ohio). 22(2)
Autocrine/paracrine transforming growth factor beta (TGF-beta) is an important regulator of stem cell quiescence and generally suppresses stem cell proliferation. However, we show here that during the first few days of an erythroid cell culture from
Autor:
Ralph M. Böhmer
Publikováno v:
Journal of hematotherapystem cell research. 12(5)
Treatment of adult blood-derived stem cells with transforming growth factor (TGF-beta) during the first 3-4 days in culture increases the proportions and absolute numbers of erythroid cells subsequently expressing fetal hemoglobin (F+ cells). The cha
Publikováno v:
Experimental cell research. 191(1)
Polyinosinic-polycytidylic acid [poly(I:C)], a synthetic double-stranded RNA, is an inhibitor of mitogen-induced proliferation of normal fibroblasts. We show that this inhibition depends strongly on cell density. While cultures with densities at or a
Autor:
Ralph M. Böhmer
Publikováno v:
Journal of Hematotherapy & Stem Cell Research; Oct2003, Vol. 12 Issue 5, p499-504, 6p