Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Ralph J. A. Maas"'
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Akademický článek
Increased peritoneal TGF-β1 is associated with ascites-induced NK-cell dysfunction and reduced survival in high-grade epithelial ovarian cancer
Autor: Ralph J. A. Maas, Janneke S. Hoogstad-van Evert, Iris M. Hagemans, Jolanda Brummelman, Diede van Ens, Paul K. J. D. de Jonge, Laura Hooijmaijers, Shweta Mahajan, Anniek B. van der Waart, Charlotte K. J. C. Hermans, Janne de Klein, Rob Woestenenk, Antonius E. van Herwaarden, Nicolaas P. M. Schaap, Somayeh Rezaeifard, Daniele V. F. Tauriello, Petra L. M. Zusterzeel, Nelleke Ottevanger, Joop H. Jansen, Willemijn Hobo, Harry Dolstra
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
Natural killer (NK) cell therapy represents an attractive immunotherapy approach against recurrent epithelial ovarian cancer (EOC), as EOC is sensitive to NK cell-mediated cytotoxicity. However, NK cell antitumor activity is dampened by suppressive f
Externí odkaz: https://doaj.org/article/fba2485f4f604077a2047c69ad71b92f
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2
CD34
Autor: Jolien M R, Van der Meer, Paul K J D, de Jonge, Anniek B, van der Waart, Alexander C, Geerlings, Jurgen P, Moonen, Jolanda, Brummelman, Janne, de Klein, Malou C, Vermeulen, Ralph J A, Maas, Nicolaas P M, Schaap, Janneke S, Hoogstad-van Evert, Petronella B, Ottevanger, Joop H, Jansen, Willemijn, Hobo, Harry, Dolstra
Publikováno v: Oncoimmunology
article-version (VoR) Version of Record
Combining natural killer (NK) cell adoptive transfer with tumor-sensitizing chemotherapy is an attractive approach against recurrent ovarian cancer (OC), as OC is sensitive to NK cell-mediated immunity. Previously, we showed that CD34+ hematopoietic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8084d4ef7b24a39f4dd64b66352196fe
https://pubmed.ncbi.nlm.nih.gov/34616589
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3
CD34+ progenitor-derived NK cell and gemcitabine combination therapy increases killing of ovarian cancer cells in NOD/SCID/IL2Rgnull mice
Autor: Janne de Klein, Paul K J D de Jonge, Willemijn Hobo, Nicolaas Schaap, Jurgen P Moonen, Alexander C Geerlings, Janneke S. Hoogstad-van Evert, Jolien M R van der Meer, Harry Dolstra, Anniek B. van der Waart, Malou C Vermeulen, Joop H. Jansen, Jolanda Brummelman, Petronella B. Ottevanger, Ralph J. A. Maas
Publikováno v: Oncoimmunology, 10
OncoImmunology, Vol 10, Iss 1 (2021)
Oncoimmunology, 10, 1
Combining natural killer (NK) cell adoptive transfer with tumor-sensitizing chemotherapy is an attractive approach against recurrent ovarian cancer (OC), as OC is sensitive to NK cell-mediated immunity. Previously, we showed that CD34+ hematopoietic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74eea731f41c6fa24b7ca31f8a8e92fd
https://doi.org/10.1080/2162402x.2021.1981049
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4
TIGIT blockade enhances functionality of peritoneal NK cells with altered expression of DNAM-1/TIGIT/CD96 checkpoint molecules in ovarian cancer
Autor: Rob Woestenenk, Vera E. Mekers, Jeannette Cany, Somayeh Rezaeifard, Alan J. Korman, Nicolaas Schaap, Paul K J D de Jonge, Joop H. Jansen, Harry Dolstra, Janneke S. Hoogstad-van Evert, Leon F.A.G. Massuger, Jolien M R van der Meer, Ralph J. A. Maas, Willemijn Hobo
Publikováno v: Oncoimmunology
article-version (VoR) Version of Record
Oncoimmunology, 9, 1
Oncoimmunology, 9
OncoImmunology, Vol 9, Iss 1 (2020)
Advanced ovarian cancer (OC) patients have a poor 5-year survival of only 28%, emphasizing the medical need for improved therapies. Adjuvant immunotherapy could be an attractive approach since OC is an immunogenic disease and the presence of tumor-in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6fd716060578090268b92db99ab95f
https://pubmed.ncbi.nlm.nih.gov/33224630
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5
Peritoneal NK cells are responsive to IL-15 and percentages are correlated with outcome in advanced ovarian cancer patients
Autor: Sophieke C.H.A. van der Steen, Jolien M R van der Meer, Willemijn Hobo, Jeannette Cany, Ralph J. A. Maas, Leon F.A.G. Massuger, Harry Dolstra, Ruud L.M. Bekkers, Janneke S. Hoogstad-van Evert, Jeffrey S. Miller, Joop H. Jansen
Publikováno v: Oncotarget, 9, 78, pp. 34810-34820
Oncotarget, 9, 34810-34820
Oncotarget
The demonstration that ovarian carcinoma (OC) is an immunogenic disease, opens opportunities to explore immunotherapeutic interventions to improve clinical outcome. In this regard, NK cell based immunotherapy could be promising as it has been demonst
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c24d726feb660811c25e179183f3b25
https://doi.org/10.18632/oncotarget.26199
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8
Cell migration through three-dimensional confining pores: speed accelerations by deformation and recoil of the nucleus
Autor: Anotida Madzvamuse, Philipp Isermann, Jan Schepens, Mariska te Lindert, Chandrasekhar Venkataraman, Feng Wei Yang, Wiljan Hendriks, Joost te Riet, Ralph J. A. Maas, Marina Krause, Katarina Wolf, Jan Lammerding
Publikováno v: Philosophical Transactions-Royal Society. Biological Sciences, 374
Philosophical Transactions of the Royal Society B: Biological Sciences
Philosophical Transactions-Royal Society. Biological Sciences, 374, 1779
Directional cell migration in dense three-dimensional (3D) environments critically depends upon shape adaptation and is impeded depending on the size and rigidity of the nucleus. Accordingly, the nucleus is primarily understood as a physical obstacle
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e87bb3c2f6c52b950a9394029ee4ca
http://hdl.handle.net/2066/206046
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