Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Ralph Giorno"'
Autor:
David A. Norris, Qutayba Hamid, Evan R. Farmer, Patrick M. Schlievert, Christine Kuhn, Donald Y.M. Leung, Jeffrey B. Travers, Ralph Giorno
Publikováno v:
Journal of Clinical Investigation. 104:1181-1189
Streptococcal and staphylococcal superantigens (SAg's) have been implicated in the pathogenesis of inflammatory skin diseases, but the mechanisms by which these toxins act are unknown. The present study assessed the ability of nanogram quantities of
Publikováno v:
Journal of Dermatological Science. 12:140-146
Candida albicans is a common pathogen which can present major problems as an opportunistic skin pathogen in patients with immunodeficiency. The exact nature of the T cell responses to C. albicans is poorly understood. The purpose of this study was to
Autor:
Donald Y.M. Leung, Michael H Kim, David A. Norris, L V Kazemi, Malak Kotb, R Skinner, Jeffrey B. Travers, Ralph Giorno, A E Trumble, J Aelion
Publikováno v:
Journal of Clinical Investigation. 96:2106-2112
Recent studies have suggested that T cells play a critical role in the pathogenesis of psoriasis. Guttate psoriasis is a well-defined form of psoriasis frequently associated with streptococcal throat infection. This study tested the hypothesis that T
Publikováno v:
Arthritis & Rheumatism. 37:376-383
Objective. To test the hypothesis that during exacerbations of systemic lupus erythematosus (SLE), endothelial cells are activated to increase their expression of adhesion molecules. Methods. Endothelial cell expression of E-selectin, vascular cell a
Publikováno v:
Journal of Investigative Dermatology. 100(3):225-228
Psoriasis is a complex inflammatory skin disease in which local vascular changes, T-cell activation, abnormal keratinocyte proliferation and differentiation, and neutrophil activation all contribute to the ongoing disease process. Because of recent i
Autor:
Sonia Durairaj, Ralph Giorno, Stephen C. Dreskin, Karen Y. Andrews, O. P. Patel, Donald A. Dibbern
Publikováno v:
Allergy & Rhinology
Allergy & Rhinology, Vol 6 (2015)
Allergy & Rhinology, Vol 6 (2015)
Background The pathophysiology of chronic idiopathic (spontaneous) urticaria (CIU) is poorly understood. Objective We hypothesized that a study of gene expression in active lesions from patients with CIU would uncover unexpected associations. Methods
Autor:
Jeanett V. Olsen, Patrick M. Schlievert, Ralph Giorno, Ole Baadsgaard, Donald Y.M. Leung, Lone Skov
Publikováno v:
The Journal of allergy and clinical immunology. 105(4)
Background: The skin of patients with inflammatory skin diseases such as atopic dermatitis is frequently colonized with Staphylococcus aureus. Colonization with S aureus has been reported to exacerbate atopic dermatitis. Recent studies have demonstra
Autor:
John Rediske, Mary Louise Skovron, H M Belmont, Goel A, Steven B. Abramson, Ralph Giorno, Ashok R. Amin, Levartovsky D
Publikováno v:
Arthritis and rheumatism. 40(10)
OBJECTIVE To investigate whether systemic lupus erythematosus (SLE) is accompanied by increased serum nitrite levels, whether active compared with inactive disease is associated with greater nitric oxide (NO) production, and whether endothelial cells
Publikováno v:
Clinical immunology and immunopathology. 71(2)
Chronic graft-versus-host disease (cGVHD) is considered to be a model for scleroderma, and vascular changes are considered to be important in that disease. We have examined the expression of intercellular adhesion molecule-1 (ICAM-1) and lymphocyte f
Autor:
Ralph Giorno, Donald Y.M. Leung, Mickey Williams, Abbie C. Celniker, Jan E. Henson, Richard J. Martin, Mark Boguniewicz
Publikováno v:
The American review of respiratory disease. 148(6 Pt 1)
Recent studies suggest that cytokines such as recombinant interferon-gamma (rIFN-gamma) may play a role in the treatment of certain respiratory conditions associated with infection and inflammation. This study was designed to determine if rIFN-gamma