Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Ralph F. Kampschmidt"'
Autor:
Marla Mesecher, Ralph F. Kampschmidt
Publikováno v:
Experimental Biology and Medicine. 179:197-200
Partially purified interleukin-1 was prepared from the murine cell line P388D1. This interleukin-1 produced fever in rabbits and the amount required to cause an increase of 1°C was determined. This dose of interleukin-1 produced neutrophilia when in
Publikováno v:
Experimental Biology and Medicine. 146:904-907
SummaryA progressive increase in plasma fibrinogen and haptoglobin occurred in rats receiving increasing doses of leuko-cytic endogenous mediator. The increases in fibrinogen occurred sooner after injections of leukocytic endogenous mediator than wit
Autor:
Ralph F. Kampschmidt
Publikováno v:
Journal of Leukocyte Biology. 36:341-355
Over the past 25 years there has been an ever-expanding interest in the mediators that control the immune response [98,133], One of these is produced by macrophages and was first called “lymphocyte activating factor” [49–51] but is now designat
Publikováno v:
Journal of Leukocyte Biology. 39:123-132
Oil-elicited rabbit macrophages stimulated by endotoxin were found to release increased amounts of interleukin 1 (IL-1) when incubated with silica. The assays used to determine the amount of IL-1 released were uptake of thymidine by mouse thymocytes,
Publikováno v:
Experimental Biology and Medicine. 155:89-93
SummaryRepeated injections of leukocytic endogenous mediator (LEM) were given every 8 hr to rats for 10 days. Peripheral blood neutrophils were elevated rapidly and after several injections were maintained at six- to eightfold normal levels. Mature b
Publikováno v:
Annals of the New York Academy of Sciences. 389:338-353
Fibrinogen has been the plasma protein most frequently studied after tissue injury. This report presents evidence that leukocytic endogenous mediator (LEM) from macrophages promotes fibrinogen synthesis. LEM has a molecular weight of 13,000-16,000, a
Publikováno v:
Experimental Biology and Medicine. 113:142-145
SummaryInjections of endotoxin will produce a rapid decrease in plasma iron concentration of normal rats. During this interval the fraction of the total plasma iron which was removed per hour was markedly increased, but the actual amount of iron remo
Autor:
West A. Clabaugh, Ralph F. Kampschmidt
Publikováno v:
Experimental Biology and Medicine. 115:681-684
SummaryRats 2, 3, 4, 5, 6 and 12 months old were inoculated with the Jensen sarcoma and the phagocytic index of the reticuloendothelial system was measured at various stages of tumor growth. The older animals bearing the Jensen tumor produced more an
Publikováno v:
Experimental Biology and Medicine. 129:580-584
SummaryBilirubin production was found to increase twofold during the first 24 hr after administering 100 μg endotoxin (intraperitoneally) to rats. A 50% increase in bilirubin production was observed in host rats 7 days after transplant of the Walker
Publikováno v:
Experimental Biology and Medicine. 112:78-81
SummaryLipopolysaccharides from gramnegative bacteria produced a marked increase in the phagocytic activity of the reticuloendothelial system in the rat 2 hours after injection. This increased phagocytic activity failed to provide additional protecti