Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Ralph F. Alderson"'
Autor:
Paul A. Moore, Ezio Bonvini, Syd Johnson, Stanford J. Stewart, Scott Koenig, Jennie P. Mather, Tony W. Liang, Claudia Fieger, Monica Licea, Jill R. Rillema, Jonathan C. Li, Ann N. Easton, Yan Chen, Tom Son, Yinhua Yang, Hua Li, Valentina Ciccarone, Steve Burke, Sergey Gorlatov, Wenjun Zhang, Ling Huang, Francine Z. Chen, Ralph F. Alderson, Deryk Loo
PDF file, 81KB, Kinetic and Equilibrium binding constants, determined by surface plasmon resonance, for binding of murine BRCA84D, RES240 and MGA271 to human and cynomolgus monkey B7-H3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3954be4c568cf141479ff5caabd87625
https://doi.org/10.1158/1078-0432.22446986.v1
https://doi.org/10.1158/1078-0432.22446986.v1
Autor:
Paul A. Moore, Ezio Bonvini, Syd Johnson, Stanford J. Stewart, Scott Koenig, Jennie P. Mather, Tony W. Liang, Claudia Fieger, Monica Licea, Jill R. Rillema, Jonathan C. Li, Ann N. Easton, Yan Chen, Tom Son, Yinhua Yang, Hua Li, Valentina Ciccarone, Steve Burke, Sergey Gorlatov, Wenjun Zhang, Ling Huang, Francine Z. Chen, Ralph F. Alderson, Deryk Loo
PDF file, 75KB, Expression level of B7-H3 on ATCC cancer cell lines as determined by FLOW cytometry with anti-B7-H3 mAb BRCA84D. Solid curves represent isotype control staining; open curves represent staining with FI.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a7396395671beca990878b868aa69d
https://doi.org/10.1158/1078-0432.22447001
https://doi.org/10.1158/1078-0432.22447001
Autor:
Paul A. Moore, Ezio Bonvini, Syd Johnson, Stanford J. Stewart, Scott Koenig, Jennie P. Mather, Tony W. Liang, Claudia Fieger, Monica Licea, Jill R. Rillema, Jonathan C. Li, Ann N. Easton, Yan Chen, Tom Son, Yinhua Yang, Hua Li, Valentina Ciccarone, Steve Burke, Sergey Gorlatov, Wenjun Zhang, Ling Huang, Francine Z. Chen, Ralph F. Alderson, Deryk Loo
PDF file, 78KB, Measurement of the absolute level of circulating B cells (CD20+; Panel A), T cells (CD3+; Panel B) and NK cells (CD159a+)Panel C) in blood samples collected from cynomolgus monkeys at the indicated days prior to administration (Day -2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6713e2ca3fa83c5b06a09b2b9865e32
https://doi.org/10.1158/1078-0432.22446992.v1
https://doi.org/10.1158/1078-0432.22446992.v1
Autor:
Paul A. Moore, Ezio Bonvini, Syd Johnson, Stanford J. Stewart, Scott Koenig, Jennie P. Mather, Tony W. Liang, Claudia Fieger, Monica Licea, Jill R. Rillema, Jonathan C. Li, Ann N. Easton, Yan Chen, Tom Son, Yinhua Yang, Hua Li, Valentina Ciccarone, Steve Burke, Sergey Gorlatov, Wenjun Zhang, Ling Huang, Francine Z. Chen, Ralph F. Alderson, Deryk Loo
PDF file, 89KB, Measurement of IL-5 (Panel A), IL-6 (Panel B) and TNF-B (Panel C) cytokine levels in serum samples collected from cynomolgus monkeys prior to infusion (Pre) or at the indicated time points following intravenous administration of PBS v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170a84c2e2cb77a54536a2580cb2eec2
https://doi.org/10.1158/1078-0432.22446995
https://doi.org/10.1158/1078-0432.22446995
Autor:
Paul A. Moore, Ezio Bonvini, Syd Johnson, Stanford J. Stewart, Scott Koenig, Jennie P. Mather, Tony W. Liang, Claudia Fieger, Monica Licea, Jill R. Rillema, Jonathan C. Li, Ann N. Easton, Yan Chen, Tom Son, Yinhua Yang, Hua Li, Valentina Ciccarone, Steve Burke, Sergey Gorlatov, Wenjun Zhang, Ling Huang, Francine Z. Chen, Ralph F. Alderson, Deryk Loo
PDF file, 204KB, Panel A: Representative reactivity of anti-B7-H3 mAb BRCA84D with frozen tissue sections of prostate, breast, colon, lung, gastric and renal cancer. Panel B: Reactivity of anti-B7-H3 mAb BRCA69D on formalin-fixed paraffin embedded no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7653e82b56feaac91704e70391b9be55
https://doi.org/10.1158/1078-0432.22447004
https://doi.org/10.1158/1078-0432.22447004
Autor:
Paul A. Moore, Ezio Bonvini, Syd Johnson, Stanford J. Stewart, Scott Koenig, Jennie P. Mather, Tony W. Liang, Claudia Fieger, Monica Licea, Jill R. Rillema, Jonathan C. Li, Ann N. Easton, Yan Chen, Tom Son, Yinhua Yang, Hua Li, Valentina Ciccarone, Steve Burke, Sergey Gorlatov, Wenjun Zhang, Ling Huang, Francine Z. Chen, Ralph F. Alderson, Deryk Loo
PDF file, 78KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230761ea819d7f1d6c27bc3eb3448720
https://doi.org/10.1158/1078-0432.22446989.v1
https://doi.org/10.1158/1078-0432.22446989.v1
Autor:
Paul A. Moore, Ezio Bonvini, Syd Johnson, Stanford J. Stewart, Scott Koenig, Jennie P. Mather, Tony W. Liang, Claudia Fieger, Monica Licea, Jill R. Rillema, Jonathan C. Li, Ann N. Easton, Yan Chen, Tom Son, Yinhua Yang, Hua Li, Valentina Ciccarone, Steve Burke, Sergey Gorlatov, Wenjun Zhang, Ling Huang, Francine Z. Chen, Ralph F. Alderson, Deryk Loo
Purpose: The goal of this research was to harness a monoclonal antibody (mAb) discovery platform to identify cell-surface antigens highly expressed on cancer and develop, through Fc optimization, potent mAb therapies toward these tumor-specific antig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b651ffb50b59ce4953c890e1b0096ce8
https://doi.org/10.1158/1078-0432.c.6520940
https://doi.org/10.1158/1078-0432.c.6520940
Autor:
Paul A. Moore, Ezio Bonvini, Syd Johnson, Stanford J. Stewart, Scott Koenig, Jennie P. Mather, Tony W. Liang, Claudia Fieger, Monica Licea, Jill R. Rillema, Jonathan C. Li, Ann N. Easton, Yan Chen, Tom Son, Yinhua Yang, Hua Li, Valentina Ciccarone, Steve Burke, Sergey Gorlatov, Wenjun Zhang, Ling Huang, Francine Z. Chen, Ralph F. Alderson, Deryk Loo
PDF file, 59KB, Expanded normal tissue IHC analysis of B7-H3 on frozen tissues with MGA271 at optimal staining concentration (4 ug/ml) and at 5x the optimal concentration (20 ug/ml). The optimal staining concentration was determined by titration on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b368e4ea7e368ec7de4b483abb2c102c
https://doi.org/10.1158/1078-0432.22446983.v1
https://doi.org/10.1158/1078-0432.22446983.v1
Autor:
Dilan Anil Patel, Ezhilarasi Chendamarai, Julie K. Ritchey, Michael P. Rettig, Leah Gehrs, Paul Moore, Ralph F. Alderson, Ezio Bonvini, Matthew Christopher, John F. DiPersio
Publikováno v:
Blood. 140:8795-8796
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca4344e8a141b9c94c7773518c3158cb
https://doi.org/10.1182/blood-2022-156943
https://doi.org/10.1182/blood-2022-156943
Autor:
Joshua Roy Basler, Lilia Babé, Peter D. Senter, Volker Schellenberger, Enrique Escandon, Ralph F. Alderson, Martin Roberge, Wei Geng, Brian E. Toki, Regina Chin, Roanna Ueda, Judith A. Fox, Tianling Chen, Amy Liu, Tessi Kanavarioti, Douglas Hodges
Publikováno v:
Bioconjugate Chemistry. 17:410-418
CC49 is a clinically validated antibody with specificity for TAG-72, a carbohydrate epitope that is overexpressed and exposed on the cell surface in a large fraction of solid malignancies. We constructed a single-chain fragment (scFv) based on CC49 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240871119dc39749e0e8b1fb0c6a9c29
https://doi.org/10.1021/bc0503521
https://doi.org/10.1021/bc0503521