Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ralph F Nelson"'
Autor:
Ciana Deveau, Xiaodong Jiao, Sachihiro C Suzuki, Asha Krishnakumar, Takeshi Yoshimatsu, J Fielding Hejtmancik, Ralph F Nelson
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008869 (2020)
We investigate mutations in trβ2, a splice variant of thrb, identifying changes in function, structure, and behavior in larval and adult zebrafish retinas. Two N-terminus CRISPR mutants were identified. The first is a 6BP+1 insertion deletion frames
Externí odkaz:
https://doaj.org/article/ea0699d690a147cf877ed1b930a3c695
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 10 (2018)
Prolonged hyperglycemia can alter retinal function, ultimately resulting in blindness. Adult zebrafish adults exposed to alternating conditions of 2% glucose/0% glucose display a 3× increase in blood sugar levels. After 4 weeks of treatment, electro
Externí odkaz:
https://doaj.org/article/fda5d7496975445f9b350fea32893beb
Autor:
Ralph F. Nelson, Annika Balraj, Tara Suresh, Leah J. Elias, Takeshi Yoshimatsu, Sara S. Patterson
Publikováno v:
eNeuro. 9(6)
Zebrafish retinal cone signals shift in spectral shape through larval, juvenile, and adult development as expression patterns of eight cone-opsin genes change. An algorithm extracting signal amplitudes for the component cone spectral types is develop
Autor:
Carl L. Gardner, Ralph F. Nelson, Steven M. Baer, Christian Ringhofer, Shaojie Chang, Sharon M. Crook, Jeremiah R. Jones
Publikováno v:
Journal of Theoretical Biology. 525:110763
The retina is a part of the central nervous system that is accessible, well documented, and studied by researchers spanning the clinical, experimental, and theoretical sciences. Here, we mathematically model the subcircuits of the outer plexiform lay