Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Ralph Eckenberg"'
1
Structural Analysis and Modeling of a Synthetic Interleukin-2 Mimetic and Its Interleukin-2Rβ2 Receptor
Autor: Thierry Rose, Jacques Thèze, Ralph Eckenberg, Jean-Louis Moreau
Publikováno v: Journal of Biological Chemistry. 278:22868-22876
Peptide p1-30, which is composed of the 30 amino-terminal residues (alpha-helix A) of human interleukin-2 (IL-2), binds as a tetramer to the dimeric IL-2Rbeta2 receptor, whereas the entire IL-2 recognizes the tricomponent receptor IL-2Ralphabetagamma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f755fa430f2b2fa92ab6424430b908
https://doi.org/10.1074/jbc.m301757200
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2
The DNA sequence and analysis of human chromosome 14
Autor: Roland Heilig, Ralph Eckenberg, Jean-Louis Petit, Núria Fonknechten, Corinne Da Silva, Laurence Cattolico, Michaël Levy, Valérie Barbe, Véronique de Berardinis, Abel Ureta-Vidal, Eric Pelletier, Virginie Vico, Véronique Anthouard, Lee Rowen, Anup Madan, Shizhen Qin, Hui Sun, Hui Du, Kymberlie Pepin, François Artiguenave, Catherine Robert, Corinne Cruaud, Thomas Brüls, Olivier Jaillon, Lucie Friedlander, Gaelle Samson, Philippe Brottier, Susan Cure, Béatrice Ségurens, Franck Anière, Sylvie Samain, Hervé Crespeau, Nissa Abbasi, Nathalie Aiach, Didier Boscus, Rachel Dickhoff, Monica Dors, Ivan Dubois, Cynthia Friedman, Michel Gouyvenoux, Rose James, Anuradha Madan, Barbara Mairey–Estrada, Sophie Mangenot, Nathalie Martins, Manuela Ménard, Sophie Oztas, Amber Ratcliffe, Tristan Shaffer, Barbara Trask, Benoit Vacherie, Chadia Bellemere, Caroline Belser, Marielle Besnard-Gonnet, Delphine Bartol–Mavel, Magali Boutard, Stéphanie Briez-Silla, Stephane Combette, Virginie Dufossé-Laurent, Carolyne Ferron, Christophe Lechaplais, Claudine Louesse, Delphine Muselet, Ghislaine Magdelenat, Emilie Pateau, Emmanuelle Petit, Peggy Sirvain-Trukniewicz, Arnaud Trybou, Nathalie Vega-Czarny, Elodie Bataille, Elodie Bluet, Isabelle Bordelais, Maria Dubois, Corinne Dumont, Thomas Guérin, Sébastien Haffray, Rachid Hammadi, Jacqueline Muanga, Virginie Pellouin, Dominique Robert, Edith Wunderle, Gilbert Gauguet, Alice Roy, Laurent Sainte-Marthe, Jean Verdier, Claude Verdier-Discala, LaDeana Hillier, Lucinda Fulton, John McPherson, Fumihiko Matsuda, Richard Wilson, Claude Scarpelli, Gábor Gyapay, Patrick Wincker, William Saurin, Francis Quétier, Robert Waterston, Leroy Hood, Jean Weissenbach
Publikováno v: Nature. 421:601-607
Chromosome 14 is one of five acrocentric chromosomes in the human genome. These chromosomes are characterized by a heterochromatic short arm that contains essentially ribosomal RNA genes, and a euchromatic long arm in which most, if not all, of the p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d820ff4ceb97c145e8557acff982ef2
https://doi.org/10.1038/nature01348
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3
Comparative analysis of BAC and whole genome shotgun sequences from an Anopheles gambiae region related to Plasmodium encapsulation
Autor: Jean Weissenbach, Karin Eiglmeier, Ralph Eckenberg, Laurence Cattolico, Hadi Quesneville, Inge Holm, Charles Roth, Véronique Anthouard, Paul T. Brey, Olivier Jaillon, Frank H. Collins, Patrick Wincker
Publikováno v: Insect Biochemistry and Molecular Biology
Insect Biochemistry and Molecular Biology, Elsevier, 2005, 35 (8), pp.799-814. ⟨10.1016/j.ibmb.2005.02.020⟩
Insect Biochemistry and Molecular Biology, 2005, 35 (8), pp.799-814. ⟨10.1016/j.ibmb.2005.02.020⟩
International audience; The only natural mechanism of malaria transmission in sub-Saharan Africa is the mosquito, generally Anopheles gambiae. Blocking malaria parasite transmission by stopping the development of Plasmodium in the insect vector would
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ad337257f921b03258cac19adef77f
https://hal.inrae.fr/hal-02683098
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5
The First α Helix of Interleukin (Il)-2 Folds as a Homotetramer, Acts as an Agonist of the IL-2 Receptor β Chain, and Induces Lymphokine-Activated Killer Cells
Autor: Franck Gesbert, Marc Bossus, Sigrid Dubois, Jacques Thèze, Jean-Louis Moreau, Pedro M. Alzari, Yannick Jacques, Thierry Rose, Diana Tello, Ralph Eckenberg, André Tartar, Hélène Gras, Salem Chouaib, Robert Weil, Michel Goldberg, Jacques Bertoglio
Publikováno v: Journal of Experimental Medicine
Journal of Experimental Medicine, 2000, 191 (3), pp.529-540. ⟨10.1084/jem.191.3.529⟩
Journal of Experimental Medicine, Rockefeller University Press, 2000, 191 (3), pp.529-540. ⟨10.1084/jem.191.3.529⟩
The Journal of Experimental Medicine
International audience; Interleukin (IL)-2 interacts with two types of functional receptors (IL-2Ralphabetagamma and IL-2Rbetagamma) and acts on a broad range of target cells involved in inflammatory reactions and immune responses. For the first time
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bea8e66fc3c9061bd3036de07f74974
https://hal-pasteur.archives-ouvertes.fr/pasteur-03144737
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6
Analysis of human IL-2/IL-2 receptor beta chain interactions: monoclonal antibody H2-8 and new IL-2 mutants define the critical role of alpha helix-A of IL-2
Autor: Jean-Claude Mazie, Xin Yuan Liu, Ralph Eckenberg, Di Xu, Jacques Bertoglio, Jean-Louis Moreau, Jacques Thèze, Pedro M. Alzari, André Tartar, Marc Bossus
Publikováno v: Cytokine
Cytokine, Elsevier, 1997, 9 (7), pp.488-498. ⟨10.1006/cyto.1996.0192⟩
Cytokine, 1997, 9 (7), pp.488-498. ⟨10.1006/cyto.1996.0192⟩
International audience; Interleukin 2 (IL-2) interacts with a receptor (IL-2R) composed of three subunits (IL-2R alpha, IL-2R beta and IL-2R gamma). IL-2R beta plays a critical role in signal transduction. An anti-human IL-2 mAb (H2-8) produced after
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eacc98ec01ad9cdc3c3bcc2e8900be9
https://hal-pasteur.archives-ouvertes.fr/pasteur-03136632
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