Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Ralph E. Purdy"'
Autor:
Jin Ma, Zhongchao Wang, Yu-Yang Zhang, Xinling Ren, Ran Zhang, Ralph E. Purdy, Huan Liu, Jin-Wen Yu, Yue Cai
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 38:683-687
Summary 1. The aim of the present study was to investigate the effects of simulated microgravity on the arterial dilatory responsiveness and l-arginine (l-Arg)–nitric oxide (NO)–cGMP pathway in the abdominal aorta of rats. 2. Twenty healthy male
Autor:
Ralph V. Clayman, Ralph E. Purdy, Michael K. Louie, Stanislav Shelkovnikov, Elspeth M. McDougall, Donald L. Pick, Adam G. Kaplan
Publikováno v:
Journal of Endourology. 25:681-685
Safe intraluminal access to the ureter and kidney is essential for endourologic procedures. Pharmacologic manipulation of ureteral smooth muscle could conceivably ease access and decrease morbidity. To minimize systemic effects, local intraluminal ad
Publikováno v:
Journal of Applied Physiology. 107:121-127
Hindlimb unweighting (HLU) of rats is a model used to mimic the cephalic fluid shift potentially involved in the orthostatic intolerance experienced by astronauts. Certain arteries in these rats exhibit a decreased contractile response to adrenergic
Publikováno v:
Vascular Pharmacology. 48:208-214
Hindlimb unweighting (HLU) in rats mimics the fluid shift experienced by astronauts and may serve as a model for ground-based orthostatic hypotension. It has been shown that the abdominal aorta of HLU rats exhibits a deficit in contractile response t
Publikováno v:
Aviation, Space, and Environmental Medicine. 78:1103-1107
Background Hindlimb unloading (HLU) is used to simulate microgravity in rats and has been shown to decrease contractile response in the abdominal aorta. The thoracic aorta has not been studied as thoroughly. Methods Wistar and Sprague-Dawley rats wer
Publikováno v:
Journal of Applied Physiology. 94:83-92
The aim of the present work was to investigate the alterations in nitric oxide synthase (NOS) expression and nitrate and nitrite (NOx) content of different arteries from simulated microgravity rats. Male Wistar rats were randomly assigned to either a
Publikováno v:
Journal of Applied Physiology. 91:789-796
Endothelial nitric oxide contributes to the vascular hyporesponsiveness to norepinephrine (NE) observed in carotid arteries from rats exposed to simulated microgravity. The goal of the present study was to determine whether a cyclooxygenase product o
Autor:
Jeffrey C. Milliken, Peter B. Smulowitz, Greg Cogert, William C. Wallace, Dan L. Serna, Chadi I. Kahwaji, Justin West, Earl Steward, Ralph E. Purdy, Ledford L. Powell
Publikováno v:
ASAIO Journal. 46:547-552
Efforts to extend myocardial preservation for transplantation by crystalloid perfusion have been limited by edema and compromised function. We hypothesized that hypothermic perfusion preservation with a polyethylene glycol (PEG) conjugated hemoglobin
Publikováno v:
Journal of Cardiovascular Pharmacology. 35:863-870
We used selective receptor antagonists to identify the receptors mediating the isometric contractile response to serotonin in control and phenylephrine (PHE)-precontracted rabbit femoral artery rings. Serotonin, in the absence of PHE, elicited monoph
Autor:
Elmar W. J. Weiler, Farhad Khalil-Manesh, Harvey C. Gonick, Bruce A. Prins, Dilip K. Sensharma, Ralph E. Purdy
Publikováno v:
American Journal of Hypertension. 12:364-373
It has been demonstrated that human plasma contains a low molecular weight sodium-potassium–stimulated adenosine triphosphatase (Na-K-ATPase) inhibitor, which can be dissociated from a circulating protein with a molecular weight of approximately 12