Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Ralph E. Kirsch"'
Publikováno v:
Hepatology. 3:170-176
Qualitative and quantitative changes in glutathione S-transferase (GSH-T) were studied in human hepatocellular carcinoma. GSH-T specific activity (/imoles per min per mg protein) was variably reduced in hepatocellular carcinoma. Similar changes were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0cbbb3b43ceec8a987fe29f467177a
https://doi.org/10.1002/hep.1840030206
https://doi.org/10.1002/hep.1840030206
Autor:
David A Marais, Richard Kirsch, Vivian Clarkson, Enid G. Shephard, Mohamed A. Jaffer, Ralph E. Kirsch, Pauline de la M. Hall, Vivienne E Woodburne
Publikováno v:
Journal of Gastroenterology and Hepatology. 18:1272-1282
Background and Aim: The methionine choline-deficient (MCD) diet leads to steatohepatitis in rodents. The aim of the present study was to investigate species, strain and sex differences in this nutritional model of non-alcoholic steatohepatitis (NASH)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7849d2905087c3f5384611b361c6cc51
https://doi.org/10.1046/j.1440-1746.2003.03198.x
https://doi.org/10.1046/j.1440-1746.2003.03198.x
Autor:
Anne V. Corrigall, Horst H. Klump, P.N. Meissner, Ralph E. Kirsch, Mbulelo H. Maneli, Lester M. Davids
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1650:10-21
The effects of various protoporphyrinogen oxidase (PPOX) mutations responsible for variegate porphyria (VP), the roles of the arginine-59 residue and the glycines in the conserved flavin binding site, in catalysis and/or cofactor binding, were examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9327c8a91a7b8dc444f21736476a0022
https://doi.org/10.1016/s1570-9639(03)00186-9
https://doi.org/10.1016/s1570-9639(03)00186-9
Autor:
Sharon L Kelly, Richard Kirsch, Trevor Sewell, Mohamed A. Jaffer, Enid G. Shephard, Ralph E. Kirsch, Vivienne E Woodburne
Publikováno v:
Biochemical Journal. 364:403-412
A biologically relevant relationship exists between neutrophils and coagulation processes. Several studies have focused on the ability of neutrophil proteases (both intracellular and membrane-associated) to degrade fibrinogen. The present study inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b2f2c0599146fbfee5f6b62b858bb5
https://doi.org/10.1042/bj20011406
https://doi.org/10.1042/bj20011406
Autor:
V. Hancock, Anne V. Corrigall, Richard J Hift, Lester M. Davids, Doreen M. Meissner, P.N. Meissner, Ralph E. Kirsch
Publikováno v:
Molecular Genetics and Metabolism. 73:91-96
Variegate porphyria is an autosomal dominant disorder of haem metabolism resulting from reduced levels of the penultimate enzyme in the pathway, protoporphyrinogen oxidase. Here we investigate the molecular basis of variegate porphyria in four non-R5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71c033600ee0829111fd3ec5f19e856
https://doi.org/10.1006/mgme.2001.3163
https://doi.org/10.1006/mgme.2001.3163
Publikováno v:
Journal of Gastroenterology and Hepatology. 15:1298-1306
Background: Neutrophil function has been reported to be abnormal in patients with cirrhosis. In order to evaluate the relative contribution of hepatocellular dysfunction and portalsystemic shunting of blood to these abnormalities, neutrophil function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9284ffce01988d62758e133073224289
https://doi.org/10.1046/j.1440-1746.2000.02232.x
https://doi.org/10.1046/j.1440-1746.2000.02232.x
Autor:
Peter Eickhaus, Christopher Eedes, Heidi Smuts, Gideon D. Knobel, Ralph E. Kirsch, Timothy J. Tucker, Simon C. Robson
Publikováno v:
Journal of Medical Virology. 61:52-58
GB virus-C and the hepatitis G virus (GBV-C/HGV) are variants of the same positive sense RNA flavivirus, initially thought to be associated with hepatitis. The tissue tropism of GBV-C/HGV in normal subjects has not been evaluated to date using an ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0586b978083370c710ece70c59391c2
https://doi.org/10.1002/(sici)1096-9071(200005)61:1<52::aid-jmv8>3.0.co
https://doi.org/10.1002/(sici)1096-9071(200005)61:1<52::aid-jmv8>3.0.co
Autor:
P.N. Meissner, Doreen M. Meissner, Richard J Hift, Ralph E. Kirsch, Lester M. Davids, Anne V. Corrigall, V. Hancock
Publikováno v:
Molecular Genetics and Metabolism. 69:323-330
Variegate porphyria is an autosomal dominant disorder of heme metabolism which results from decreased activity of the enzyme protoporphyrinogen oxidase. Clinically, the disease manifests postpubertally and is characterized by photocutaneous sensitivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734be9077dfd430f756719bacba097c5
https://doi.org/10.1006/mgme.2000.2975
https://doi.org/10.1006/mgme.2000.2975
Autor:
Eric R. Lemmer, Walter F. O. Marasas, Enid G. Shephard, J. Peter Cruse, Ralph E. Kirsch, Stefan Abel, Wentzel C. A. Gelderblom, Beverley L Seymour, Pauline de la M. Hall
Publikováno v:
Cancer Letters. 146:207-215
The present study was performed to determine whether excess hepatic iron modulates the cancer-initiating and promoting properties of FB1. Thirty-eight male F344 rats were divided into four dietary treatment groups: (i) control diet (AIN, n = 8); (ii)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7609f85c3cfa4875ff5b92664fb3232f
https://doi.org/10.1016/s0304-3835(99)00274-8
https://doi.org/10.1016/s0304-3835(99)00274-8
Publikováno v:
Journal of Medical Virology. 59:52-59
GB virus C/hepatitis G virus (GBV-C/HGV) has been characterised as a novel flavivirus, and to date three known genotypes have been cloned. Greater genetic variation of GBV-C/HGV has been demonstrated in West African isolates, but no major deletions h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a45fd2a1fd080e305f2606868702eba
https://doi.org/10.1002/(sici)1096-9071(199909)59:1<52::aid-jmv9>3.0.co
https://doi.org/10.1002/(sici)1096-9071(199909)59:1<52::aid-jmv9>3.0.co