Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ralph E. Bowman"'
Autor:
Nigel Walker, Robert W. Steele, Keith Whiting, Mark A. E. Bowman, Paul J. Harris, Davies Roy Victor, Ralph E. Bowman, Gerry Haran, H. John Smith
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 17:137-154
Exposure of the N -methoxycarbonyl-bicyclic-keto-acid 5 (improved preparation) to the Barnick β -keto-acid synthesis 1 yielded an aqueous solution of the sodium salts of the β -keto-acids 26 and 27 which on heating at 60-65°C furnished the N -meth
Publikováno v:
Journal of Pharmacy and Pharmacology. 48:160-171
The synthesis of the 9α- and 9β-epimers of 8, 9, 10, 1 1α-tetrahydro-7αH-7, 11-methano-12, 12-dimethylcycloocta [de] naphthyl-9-amine is described.
Autor:
Ralph E. Bowman, Mark A. E. Bowman
Publikováno v:
ChemInform. 30
Autor:
Mark A E, Bowman, Ralph E, Bowman, Roy V, Davies, Gerry, Haran, Paul J, Harris, H John, Smith, Robert W, Steele, Nigel, Walker, Keith, Whiting
Publikováno v:
Journal of enzyme inhibition and medicinal chemistry. 17(3)
Exposure of the N-methoxycarbonyl-bicyclic-keto-acid 5 (improved preparation) to the Barnick beta-keto-acid synthesis yielded an aqueous solution of the sodium salts of the beta-keto-acids 26 and 27 which on heating at 60-65 degrees C furnished the N
Autor:
Mark A. E. Bowman, Ralph E. Bowman
Publikováno v:
Journal of Chemical Research. 23:94-95
Reaction of the N-formyl enol-lactone 4 and the corresponding N-acetyl 10 and N-methoxycarbonyl 11 derivatives with bis(trimethylsilyl)potassiomalonate in THF at 60°C followed by treatment with aqueous sodium hydrogen carbonate and cyclisation as ab
Autor:
Mark A. E. Bowman, Ralph E. Bowman
Publikováno v:
Journal of Chemical Research. :94-95
Reaction of the N-formyl enol-lactone 4 and the corresponding N-acetyl 10 and N-methoxycarbonyl 11 derivatives with bis(trimethylsilyl)potassiomalonate in THF at 60°C followed by treatment with aqueous sodium hydrogen carbonate and cyclisation as ab
Autor:
Ralph E. Bowman
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :1897-1903
Two attempts to synthesise the tricyclic α-keto-amide (6) are described. In the first, 1,2,3,4-tetradihydro-2-methylaminonaphthalen-1-one hydrochloride (3) was allowed to react with pyridine–hydroxymaleic anhydride at –20 °C and then at room te
Autor:
Ralph E. Bowman
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :2126-2133
The alkylation of a number of α-amidoketones in the 3,4-dihydro-naphthalen-1(2H)-one and -acenaphthen-5(2aH)-one series, involving treatment with sodium hydride (1 or 2 mol equiv.) in dimethylformamide solution and subsequent reaction with alkyl hal
Publikováno v:
Journal of Medicinal and Pharmaceutical Chemistry. 5:1159-1176
Autor:
Harry O. J. Collier, Nigel E. Webb, Ralph E. Bowman, Ian M. Lockhart, Michael Wright, Cyril Schneider
Publikováno v:
Journal of Medicinal Chemistry. 16:1181-1183