Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ralph E. Nothdurft"'
Publikováno v:
Journal of Microscopy. 247:202-207
Although single-photon fluorescence lifetime imaging microscopy (FLIM) is widely used to image molecular processes using a wide range of excitation wavelengths, the captured emission of this technique is confined to the visible spectrum. Here, we exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2c150f54b00c0923850d81e28ab8d0e
https://doi.org/10.1111/j.1365-2818.2012.03634.x
https://doi.org/10.1111/j.1365-2818.2012.03634.x
The specificity of both molecular and functional photoacoustic (PA) images depends on the accuracy of the photoacoustic absorption spectroscopy. Because the PA signal is a product of both the optical absorption coefficient and the local light fluence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68ba7efa95049559c403476279aee3e
https://resolver.caltech.edu/CaltechAUTHORS:20180920-130935097
https://resolver.caltech.edu/CaltechAUTHORS:20180920-130935097
Autor:
Samuel Achilefu, Walter J. Akers, Chinnasamy Muthiah, Joseph P. Culver, Ralph E. Nothdurft, Marcin Ptaszek, Dewey Holten, Hooi Ling Kee
Publikováno v:
SPIE Proceedings.
Chlorin-bacteriochlorin dyads as a new class of near-infrared fluorophores were synthesized and spectroscopically characterized. Each dyad is comprised of a chlorin macrocycle (free base or zinc chelate) as an energy donor (and absorber) and a free b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a7081a59f982fbbb801aab9125052ac
https://doi.org/10.1117/12.842007
https://doi.org/10.1117/12.842007
Publikováno v:
Biomedical Optics and 3-D Imaging.
We examine the fractional contributions of individual fluorophore in heterogeneous samples, previously demonstrated in cuvette and FLIM, with diffuse optical tomography. Experimental results from phantoms are compared with simulations at multiple fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7186fdd657f58eb5a88fea7efb99d70f
https://doi.org/10.1364/biomed.2010.bsud50
https://doi.org/10.1364/biomed.2010.bsud50
Publikováno v:
Biomedical Optics and 3-D Imaging.
Diffuse optical tomography and photoacoustic tomography were combined to measure the optical absorption coefficient of a tissue mimicking phantom. Heterogeneous fluence maps were calculated from DOT absorption reconstructions and used to correct PAT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b5fae144e23959d0f49865bb2517a21
https://doi.org/10.1364/biomed.2010.btud24
https://doi.org/10.1364/biomed.2010.btud24
Autor:
Sachin V. Patwardhan, Ralph E. Nothdurft, Samuel Achilefu, Yunpeng Ye, Joseph P. Culver, Walter J. Akers
Publikováno v:
Journal of biomedical optics. 14(2)
Local molecular and physiological processes can be imaged in vivo through perturbations in the fluorescence lifetime (FLT) of optical imaging agents. In addition to providing functional information, FLT methods can quantify specific molecular events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb36bde3fe552385522374af27a8215
https://pubmed.ncbi.nlm.nih.gov/19405734
https://pubmed.ncbi.nlm.nih.gov/19405734
Autor:
David F. Bocian, Chinnasamy Muthiah, James R. Diers, Ralph E. Nothdurft, Marcin Ptaszek, Hooi Ling Kee, Dazhong Fan, Dewey Holten, Joseph P. Culver, Jonathan S. Lindsey
Publikováno v:
Photochemistry and photobiology. 84(5)
New classes of synthetic chlorin and bacteriochlorin macrocycles are characterized by narrow spectral widths, tunable absorption and fluorescence features across the red and near-infrared (NIR) regions, tunable excited-state lifetimes (1 to10 ns) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52c602c854c36e1434217defa29383d
https://pubmed.ncbi.nlm.nih.gov/18673324
https://pubmed.ncbi.nlm.nih.gov/18673324
Publikováno v:
Biomedical Optics.
Fluorescent lifetime provides a rich approach to quantitative molecular in vivo imaging. Here we report in vivo FLT-tomography using full spatial sampling for 3-D localization, and time-resolved (up to >1 GHz) analysis of lifetime contrasts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c2eae7e8f45fba7b97c32754cc27de4
https://doi.org/10.1364/biomed.2008.bwe2
https://doi.org/10.1364/biomed.2008.bwe2
Publikováno v:
Journal of Biomedical Optics. 16:096016
The specificity of molecular and functional photoacoustic (PA) images depends on the accuracy of the photoacoustic absorption spectroscopy. The PA signal is proportional to the product of the optical absorption coefficient and local light fluence; qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76a2f480b4480e398d9e198e4145de0
https://doi.org/10.1117/1.3626212
https://doi.org/10.1117/1.3626212
Autor:
Ralph E. Nothdurft, Sachin V. Patwardhan, Walter Akers, Yunpeng Ye, Samuel Achilefu, Joseph P. Culver
Publikováno v:
Journal of Biomedical Optics; Mar2009, Vol. 14 Issue 2, p024004-024004-7, 1p