Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ralph C. Kolbeck"'
Influence of Ageing on the Fatigability of Isolated Mouse Skeletal Muscles from Mature and Aged Mice
Publikováno v:
Experimental Physiology. 87:77-82
We investigated the influence of ageing on the fatiguing characteristics of the mouse extensor digitorum longus (EDL) muscle as compared to those of the soleus muscle. Fatigue was produced by an intermittent stimulation protocol. We report for mature
Autor:
Thomas M. Nosek, Richard C. Conover, Marco Brotto, Ruben Mestril, David A. Essig, Ralph C. Kolbeck, Wolfgang H. Dillmann
Publikováno v:
Physiological Genomics. 4:25-33
The influence of inducible heat stress proteins on protecting contracting skeletal muscle against fatigue-induced injury was investigated. A line of transgenic mice overexpressing the inducible form of the 72-kDa heat shock protein (HSP72) in skeleta
Publikováno v:
Pharmacology Biochemistry and Behavior. 42:645-650
Incubated guinea pig tracheal smooth muscle exhibited both positive and negative inotropic responses to a variety of crown ether analogs that ranged in size from 12-crown-4 to 30-crown-10 and included molecules whose lipophilicity was modified by the
Publikováno v:
American journal of respiratory and critical care medicine. 156(1)
This study test the hypothesis that a temporal relationship exists between the production of superoxide anion (O2-) and the contractile activity of perfused rat diaphragm. O2- levels were determined minute to minute by measuring the reduction of cyto
Publikováno v:
Biology of reproduction. 45(2)
Progesterone and several progesterone metabolites are capable of inhibiting uterine contractility. Some progesterone metabolites have shown little or no affinity for the progesterone receptor but have been found to be potent modulators of the GABAA r
Publikováno v:
European Journal of Cancer (1965). 13:793-800
Acid-base equilibrium in two groups of cancer patients, one with newly diagnosed bronchogenic cancer and one with various solid tumors, was compared to that of a group of normal volunteers and a group of hospitalized patients with diverse diseases. A
Autor:
William A. Speir, Ralph C. Kolbeck
Publikováno v:
American Review of Respiratory Disease. 139:139-145
The ability of theophylline to limit diaphragmatic fatigue and to improve contractility appears to be dependent upon alterations in calcium metabolism. The mechanism responsible for these actions, however, remains unclear. We used perfused, contracti
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 67:1442-1447
The influence of hydrocortisone (11β,17α,21-trihydroxy-pregn-4-ene-3,20-dione) or of methylprednisolone (6α-methyl-11β,17α-21-trihydroxy-1,4-pregnadiene-3,20-dione) on the response of airway smooth muscle to a variety of β-adrenergic bronchodil
Autor:
Martin J. Frank, Ralph C. Kolbeck
Publikováno v:
Journal of Molecular and Cellular Cardiology. 17:243-253
A new method is described for making direct measurements of compartmentalized subcellular stores of calcium in the isolated perfused dog heart. Cellular calcium was immobilized by freezing the myocardium in diastole with an extremely cold fluorocarbo
Autor:
Ralph C. Kolbeck, William A. Speir
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 65:1165-1170
Contractile sensitivity and reactivity to α- and β-adrenoceptor stimulation was studied in incubated rabbit pulmonary artery cylindrical segments of differing diameters. Distinct differences were noted between the responses of extra- and intra-pulm