Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ralph B. Puchalski"'
Autor:
Nameeta Shah, Pavan M. Hallur, Raksha A. Ganesh, Pranali Sonpatki, Divya Naik, Komal Prasad Chandrachari, Ralph B. Puchalski, Aditya Chaubey
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Glioblastoma is the most lethal primary malignant brain tumor in adults. Simplified two-dimensional (2D) cell culture and neurospheres in vitro models fail to recapitulate the complexity of the tumor microenvironment, limiting its ability to
Externí odkaz:
https://doaj.org/article/761cbb7452034623974eb079afdf2556
Autor:
Adrianne L. Jenner, Munisha Smalley, David Goldman, William F. Goins, Charles S. Cobbs, Ralph B. Puchalski, E. Antonio Chiocca, Sean Lawler, Paul Macklin, Aaron Goldman, Morgan Craig
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104395- (2022)
Summary: Oncolytic viruses (OVs) are emerging cancer immunotherapy. Despite notable successes in the treatment of some tumors, OV therapy for central nervous system cancers has failed to show efficacy. We used an ex vivo tumor model developed from hu
Externí odkaz:
https://doaj.org/article/ce0d47aff0b143b1858eb624b2a4a00d
Autor:
Adrianne L. Jenner, Munisha Smalley, David Goldman, William F. Goins, Charles S. Cobbs, Ralph B. Puchalski, E. Antonio Chiocca, Sean Lawler, Paul Macklin, Aaron Goldman, Morgan Craig
Publikováno v:
iScience. 25(6)
Oncolytic viruses (OVs) are emerging cancer immunotherapy. Despite notable successes in the treatment of some tumors, OV therapy for central nervous system cancers has failed to show efficacy. We used an
Autor:
Divya Naik, Aditya Chaubey, Komal Prasad Chandrachari, Raksha A. Ganesh, Pavan M. Hallur, Pranali Sonpatki, Ralph B. Puchalski, Nameeta Shah
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Glioblastoma is the most lethal primary malignant brain tumor in adults. Simplified two-dimensional (2D) cell culture and neurospheres in vitro models fail to recapitulate the complexity of the tumor microenvironment, limiting its ability to predict
Autor:
Waldemar Debinski, Glenn J. Lesser, Lance D. Miller, Annette J. Johnson, Jordan A. Holmes, Christina K. Cramer, Stephen B. Tatter, Emory R. McTyre, Ralph B. Puchalski, Michael H. Soike, Anna K. Paulsson, Ryan T. Mott, Nameeta Shah, Adrian W. Laxton, William H. Hinson, Michael D. Chan, Hui-Wen Lo, Roy E. Strowd
Publikováno v:
Neuroradiology
PURPOSE: For glioblastoma (GBM), imaging response (IR) or pseudoprogression (PSP) is frequently observed after chemoradiation and may connote a favorable prognosis. With tumors categorized by the Cancer Genome Atlas Project (mesenchymal, classical, n
Autor:
Greg Foltz, Parvinder Hothi, Ali Kriedberg, Krissy Brouner, David Feng, Chantal Murthy, Robert Howard, Robert C. Rostomily, David Sandman, Eric Olson, Nadezhda Dotson, Nameeta Shah, Guangyu Gu, Kris Bickley, Lydia Ng, Nika Hejazinia, John W. Phillips, Leonard Kuan, Charles Cobbs, Garrett Gee, Tim A. Dolbeare, Tsega Desta, Shiella Caldejon, Kiet Ngo, Haley Gittleman, Andrew F. Boe, Hwahyung Lee, Rachel A. Dalley, Steven J. White, Chris Lau, Bart Keogh, Graham Stockdale, Lindsey Gourley, Fuhui Long, Darren Bertagnolli, Andrew Sodt, Michael Hawrylycz, Amanda Ebbert, Jill S. Barnholtz-Sloan, David Rosen, Michael S. Fisher, Antonio Iavarone, Ed S. Lein, Stephanie Butler, Patrick J. Cimino, Tracy Lemon, Zack Riley, Allan R. Jones, Megha S Uppin, Mike Chapin, Naveed Mastan, Kimberly A. Smith, Michael E. Berens, Clifford R. Slaughterbeck, Aaron Szafer, Nick Dee, Wayne Wakeman, John G. Hohmann, Benjamin W. Gregor, Suvro Datta, Felix Lee, Ralph B. Puchalski, Melissa Reding, Nadiya V. Shapovalova, Xu Feng, Amy Bernard, Jae Guen Yoon, Erika Mott, Jeremy A. Miller, Justin D. Lathia, Steve R. Nomura, Steven Rostad, Kevin M. Joines, Paul Wohnoutka, Jeff Goldy, Don Marsh, Farrokh Farrokhi, Michael Lankerovich, C. Dirk Keene, Chinh Dang
Publikováno v:
Science (New York, N.Y.). 360(6389)
Anatomically correct tumor genomics Glioblastoma is the most lethal form of human brain cancer. The genomic alterations and gene expression profiles characterizing this tumor type have been widely studied. Puchalski et al. created the Ivy Glioblastom
Autor:
Aneta Czaplinska, Aimee L. Desaki, Maureen P. Howell, Bryan I. Smith, Kevin S. Brockway, Ben J. Duncan, Annabel R. Laramee, Shanna R. Fischer, Tsuey-Ming Chen, Reena Kawal, Nancy Ao, Agnes J. Liang, Amy Bernard, Casey Faber, Ed S. Lein, Geralyn J. Orta, Kevin R. Halverson, Jennifer G. Dougherty, Chinh Dang, Cliff Frensley, Caroline C. Overly, Judith J. Morgan, Murat B. Yaylaoglu, Mark S. Boguski, Lee R. Varnam, Susan M. Sunkin, Crissa K. Wolkey, Amanda Ebbert, Matthew J.A. Wood, Paul Wohnoutka, Benjamin A.C. Facer, Li Chen, Jesse Michaels, James H. Lake, Carey D. Teemer, Rebecca A. Johnson, Axel Visel, Marty Mortrud, Michael Hawrylycz, Christina Thaller, Nerick Mosqueda, Victoria Y. Wong, Tim A. Dolbeare, Xu Feng Yuan, Mei Chi Chin, Marcos J. Ruiz, Carol L. Thompson, Katherine Schaffnit, Theresa A. Zwingman, Sayan Dev Pathak, Tracy Lemon, Lydia Ng, Jimmy Chong, Lili K. Estin, Simon Smith, Rob Young, Kirk D. Larsen, Joshua J. Royall, Randy Ng, Rachel H. Knapik, Mikael Ayres, Nick Dee, Sheana Parry, Ray M. Whitlock, Kenda-Ruth Stumpf, Nadiya V. Shapovalova, Emi J. Byrnes, Taz Sivisay, Matthew R. Hart, Chihchau L. Kuan, Owen C. Pearson, Ellen Diep, Nadia R. Sarno, Madhavi Sutram, Andrew F. Boe, Clifford R. Slaughterbeck, Zackery L. Riley, Rebecca J. Morgan, Hong-Wei Dong, Tsega Desta, Patrick T. Karr, Andy J. Sodt, John G. Hohmann, Suvro Datta, Stephen A. Rowland, Tu H. Pak, Ralph B. Puchalski, Lin Chen, Nick N. Stewart, Ying Liu, Hannah R. Rockett, Brian L. Youngstrom, Darren P. Jeung, Lon T. Luong, Matthew J. Donelan, Amy Bensinger, Katie J. Glattfelder, Bin Zhang, Allan R. Jones, Gregor Eichele, Rick Fields, Sabrina N. Gates, Kimberly A. Smith, Angelene Tam, Brian E. Crook, Tim P. Fliss, Jolene Kidney, Christopher Lau
Publikováno v:
Nature. 445:168-176
Molecular approaches to understanding the functional circuitry of the nervous system promise new insights into the relationship between genes, brain and behaviour. The cellular diversity of the brain necessitates a cellular resolution approach toward
Autor:
Nguyen D. Nguyen, Ralph B. Puchalski, Christine C. Chang, Jiesheng Kang, John H. Teeter, Stephen P. Brazier
Publikováno v:
Journal of Neurochemistry. 76:1465-1474
The gustatory system of channel catfish is widely studied for its sensitivity to amino acids. As a first step in identifying the molecular components that play a role in taste transduction in catfish, we cloned the full-length cDNA for Kv2-catfish, a
Publikováno v:
Neuro-Oncology. 18:vi186-vi186
Publikováno v:
Anatomical record (Hoboken, N.J. : 2007). 295(5)
Interpretation of the new wealth of gene expression and molecular mechanisms in the developing mouse spinal cord requires an accurate anatomical base on which data can be mapped. Therefore, we have assembled a spinal cord atlas of the P4 mouse to fac