Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ralph A. Crisostomo"'
Autor:
Elizabeth K. Benitez, Anastasia Lomova Kaufman, Lilibeth Cervantes, Danielle N. Clark, Paul G. Ayoub, Shantha Senadheera, Kyle Osborne, Julie M. Sanchez, Ralph Valentine Crisostomo, Xiaoyan Wang, Nina Reuven, Yosef Shaul, Roger P. Hollis, Zulema Romero, Donald B. Kohn
Publikováno v:
Frontiers in Genome Editing, Vol 2 (2020)
Monogenic disorders of the blood system have the potential to be treated by autologous stem cell transplantation of ex vivo genetically modified hematopoietic stem and progenitor cells (HSPCs). The sgRNA/Cas9 system allows for precise modification of
Externí odkaz:
https://doaj.org/article/e020611151d74c03b1efb0d76272a5c3
Autor:
Ralph Valentine Crisostomo, Charumathi Raghuraman, Justin P. Wingett, James Cai, Fauna Yarza, Gabriel A. Subuyuj, Paula Roszczenko-Jasińska, Caitlin A. Hoeber, Elena M. Ayala, Huong N. Vu, Erik J. Clippard, Nicholas F. Lien, Norma C. Martinez-Gomez, Elizabeth Skovran, Richard T. Ngo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific reports, vol 10, iss 1
Scientific Reports
Lanthanide elements have been recently recognized as “new life metals” yet much remains unknown regarding lanthanide acquisition and homeostasis. In Methylorubrum extorquens AM1, the periplasmic lanthanide-dependent methanol dehydrogenase XoxF1 p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1583a38e101674a6f816a967757292bf
http://link.springer.com/article/10.1038/s41598-020-69401-4
http://link.springer.com/article/10.1038/s41598-020-69401-4
Autor:
Ryo Yamamoto, Maiko Morita, Reiko Ishida, Ralph Valentine Crisostomo, Misako Kikuchi, Hiromitsu Nakauchi, Adam C. Wilkinson, Motoo Watanabe, Kyle M. Loh, Kazuhiro Sudo, Yukio Nakamura, Satoshi Yamazaki
Publikováno v:
Nature
Multipotent self-renewing haematopoietic stem cells (HSCs) regenerate the adult blood system after transplantation1, which is a curative therapy for numerous diseases including immunodeficiencies and leukaemias2. Although substantial effort has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97be6977a7ec871f1a133c6f07913bd7
https://doi.org/10.1038/s41586-019-1244-x
https://doi.org/10.1038/s41586-019-1244-x
Publikováno v:
Methods in enzymology. 650
Transposon mutagenesis utilizes transposable genetic elements that integrate into a recipient genome to generate random insertion mutations which are easily identified. This forward genetic approach has proven powerful in elucidating complex processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec511501fb4698a426252333b86f647d
https://pubmed.ncbi.nlm.nih.gov/33867020
https://pubmed.ncbi.nlm.nih.gov/33867020
Publikováno v:
Rare-Earth Element Biochemistry: Methanol Dehydrogenases and Lanthanide Biology ISBN: 9780128238561
Transposon mutagenesis utilizes transposable genetic elements that integrate into a recipient genome to generate random insertion mutations which are easily identified. This forward genetic approach has proven powerful in elucidating complex processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f5110510fad30a55434a912902cf712
https://doi.org/10.1016/bs.mie.2021.01.015
https://doi.org/10.1016/bs.mie.2021.01.015
Autor:
Shantha Senadheera, Julie M. Sanchez, Paul G. Ayoub, Nina Reuven, Danielle N. Clark, Zulema Romero, Donald B. Kohn, Elizabeth K. Benitez, Anastasia Lomova Kaufman, Roger P. Hollis, Ralph Valentine Crisostomo, Lilibeth Cervantes, Kyle Osborne, Yosef Shaul, Xiaoyan Wang
Publikováno v:
Frontiers in Genome Editing, Vol 2 (2020)
Frontiers in Genome Editing
Frontiers in Genome Editing
Monogenic disorders of the blood system have the potential to be treated by autologous stem cell transplantation of ex vivo genetically modified hematopoietic stem and progenitor cells (HSPCs). The sgRNA/Cas9 system allows for precise modification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f4d1d455b4aa2cff2cd59d20350b97
https://doi.org/10.3389/fgeed.2020.601541
https://doi.org/10.3389/fgeed.2020.601541
Autor:
Richard T. Ngo, Gabriel A. Subuyuj, Nicholas F. Lien, Ralph Valentine Crisostomo, Erik J. Clippard, Elena M. Ayala, James Cai, Paula Roszczenko-Jasińska, Caitlin A. Hoeber, Huong N. Vu, Norma Cecilia Martinez-Gomez, Justin P. Wingett, Elizabeth Skovran, Charumathi Raghuraman, Fauna Yarza
Lanthanide elements have been recently recognized as “new life metals” for diverse environmental microorganisms including Gram-negative methylotrophic bacteria and strains ofPseudomonasandBradyrhizobium. Yet much remains unknown regarding lanthan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ced8a92c3fc49fa922e5f73b25e973
Autor:
Michael E. Geisser, Ryan Demirjian, David J. Kennedy, David S. Fitch, Ralph A. Crisostomo, Mathew Smuck
Publikováno v:
The Spine Journal. 15:1415-1421
Background context Medial branch radiofrequency neurotomy (RFN) is a common treatment for zygapophyseal joint pain. The lumbar medial branch innervates these joints and adjacent structures. The impact of the intended neurotomy on these structures rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f452002b055a5dc3c1631a6868ea1388
https://doi.org/10.1016/j.spinee.2013.06.096
https://doi.org/10.1016/j.spinee.2013.06.096
Autor:
Reiko Ishida, Misako Kikuchi, Ryo Yamamoto, Satoshi Yamazaki, Kazuhiro Sudo, Maiko Morita, Kyle M. Loh, Adam C. Wilkinson, Ralph Valentine Crisostomo, Yukio Nakamura, Hiromitsu Nakauchi, Motoo Watanabe
Publikováno v:
Experimental Hematology. 76:S42
The self-renewal of multipotent hematopoietic stem cells (HSCs) is key for life-long maintenance of the blood system and the curative capacity of clinical HSC transplantation. However, while in vivo HSC self-renewal capacity has been well-described,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d5cb3b517a6e161cd4e8f39676740ec
https://doi.org/10.1016/j.exphem.2019.06.276
https://doi.org/10.1016/j.exphem.2019.06.276
Autor:
Reiko Ishida, Misako Kikuchi, Motoo Watanabe, Yukio Nakamura, Satoshi Yamazaki, Hiromitsu Nakauchi, Kazuhiro Sudo, Ryo Yamamoto, Ralph Valentine Crisostomo, Kyle M. Loh, Maiko Morita, Adam C. Wilkinson
Publikováno v:
Nature. 571:E12-E12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d299ea04412816856a06e85996f07aa
https://doi.org/10.1038/s41586-019-1395-9
https://doi.org/10.1038/s41586-019-1395-9