Zobrazeno 1 - 10
of 362
pro vyhledávání: '"Ralph A. Tripp"'
Autor:
David E. Martin, Ralph A. Tripp
Publikováno v:
Frontiers in Virology, Vol 4 (2024)
Externí odkaz:
https://doaj.org/article/5cf169743a8e4b839a5bd3821baef955
Autor:
Yanjun Yang, Hao Li, Les Jones, Jackelyn Murray, Hemant Naikare, Yung‐Yi C. Mosley, Teddy Spikes, Sebastian Hülck, Ralph A. Tripp, Bin Ai, Yiping Zhao
Publikováno v:
Advanced Materials Interfaces, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract This study presents an integrated approach combining surface‐enhanced Raman spectroscopy (SERS) with a specialized deep learning algorithm, SFNet, to offer a rapid, accurate, and label‐free alternative for COVID‐19 diagnosis and viral
Externí odkaz:
https://doaj.org/article/0eaf7b2aefa04721aa02b8f8b751ef33
Autor:
Maya Michon, Andreas Müller-Schiffmann, Anuradha F. Lingappa, Shao Feng Yu, Li Du, Fred Deiter, Sean Broce, Suguna Mallesh, Jackelyn Crabtree, Usha F. Lingappa, Amanda Macieik, Lisa Müller, Philipp Niklas Ostermann, Marcel Andrée, Ortwin Adams, Heiner Schaal, Robert J. Hogan, Ralph A. Tripp, Umesh Appaiah, Sanjeev K. Anand, Thomas W. Campi, Michael J. Ford, Jonathan C. Reed, Jim Lin, Olayemi Akintunde, Kiel Copeland, Christine Nichols, Emma Petrouski, Ana R. Moreira, I-ting Jiang, Nicholas DeYarman, Ian Brown, Sharon Lau, Ilana Segal, Danielle Goldsmith, Shi Hong, Vinod Asundi, Erica M. Briggs, Ngwe Sin Phyo, Markus Froehlich, Bruce Onisko, Kent Matlack, Debendranath Dey, Jaisri R. Lingappa, Dharma M. Prasad, Anatoliy Kitaygorodskyy, Dennis Solas, Homer Boushey, John Greenland, Satish Pillai, Michael K. Lo, Joel M. Montgomery, Christina F. Spiropoulou, Carsten Korth, Suganya Selvarajah, Kumar Paulvannan, Vishwanath R. Lingappa
Publikováno v:
Open Biology, Vol 14, Iss 6 (2024)
We present a novel small molecule antiviral chemotype that was identified by an unconventional cell-free protein synthesis and assembly-based phenotypic screen for modulation of viral capsid assembly. Activity of PAV-431, a representative compound fr
Externí odkaz:
https://doaj.org/article/ab895c6ab92c405ab16479c74bcf64ea
Autor:
Ralph A. Tripp
Publikováno v:
Expert Review of Vaccines, Vol 22, Iss 1, Pp 871-875 (2023)
Introduction Influenza virus changes its genotype through antigenic drift or shift making it difficult to develop immunity to infection or vaccination. Zoonotic influenza A virus (IAV) strains can become established in humans. Several impediments to
Externí odkaz:
https://doaj.org/article/747af91b5d4e402898a616dea9383a8a
Publikováno v:
Viruses, Vol 16, Iss 7, p 1087 (2024)
Human metapneumovirus (HMPV) is an important cause of acute respiratory tract infection and causes significant morbidity and mortality. There is no specific antiviral drug to treat HMPV or vaccine to prevent HMPV. This study determined if probenecid,
Externí odkaz:
https://doaj.org/article/3aa158ab962b40498e9c110209287ab8
Autor:
Z Beau Reneer, Harrison C Bergeron, Stephen Reynolds, Elena Thornhill-Wadolowski, Lan Feng, Marcin Bugno, Agnieszka D Truax, Ralph A Tripp
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0297833 (2024)
Influenza viruses cause epidemics and can cause pandemics with substantial morbidity with some mortality every year. Seasonal influenza vaccines have incomplete effectiveness and elicit a narrow antibody response that often does not protect against m
Externí odkaz:
https://doaj.org/article/8cca0fe77205435b98ee37f83f17170a
Autor:
Harrison C. Bergeron, Jackelyn Murray, Maria G. Juarez, Samuel J. Nangle, Rebecca M. DuBois, Ralph A. Tripp
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionRespiratory syncytial virus (RSV) can cause lower respiratory tract disease in infants and elderly populations. Despite decades of research, there remains no safe and approved RSV vaccine. Previously, we showed that an RSV G glycoprotein
Externí odkaz:
https://doaj.org/article/70ec8765a0234546b59a0929c86fe3b4
Autor:
Jackelyn Murray, David E. Martin, Sarah Hosking, Nichole Orr-Burks, Robert J. Hogan, Ralph A. Tripp
Publikováno v:
Viruses, Vol 16, Iss 1, p 152 (2024)
Avian influenza (AI) viruses cause infection in birds and humans. Several H5N1 and H7N9 variants are highly pathogenic avian influenza (HPAI) viruses. H5N1 is a highly infectious bird virus infecting primarily poultry, but unlike other AIs, H5N1 also
Externí odkaz:
https://doaj.org/article/c244c4c82587489cad1b76cb4dbc4d7e
Publikováno v:
BioTechniques, Vol 72, Iss 6, Pp 263-272 (2022)
Coronavirus disease 2019 is a public health challenge requiring rapid testing for the detection of infections and transmission. Nucleic acid amplification tests targeting SARS coronavirus 2 (CoV2) are used to detect CoV2 in clinical samples. Real-tim
Externí odkaz:
https://doaj.org/article/fd5532efaabe474b855ef6c6c69f3e5e
Publikováno v:
Therapeutic Advances in Infectious Disease, Vol 10 (2023)
Background: Respiratory syncytial virus (RSV) is a poor inducer of antiviral interferon (IFN) responses which result in incomplete immunity and RSV disease. Several RSV proteins alter antiviral responses, including the non-structural proteins (NS1, N
Externí odkaz:
https://doaj.org/article/1ef21606933c49368af252c277503990