Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Ralph, Burkhardt"'
Autor:
Janne Pott, Azin Kheirkhah, Jesper R. Gadin, Marcus E. Kleber, Graciela E. Delgado, Holger Kirsten, Lukas Forer, Stefanie M. Hauck, Ralph Burkhardt, Hubert Scharnagl, Markus Loeffler, Winfried März, Joachim Thiery, Christian Gieger, Annette Peters, Angela Silveira, Ferdinand van’t Hooft, Florian Kronenberg, Markus Scholz
Publikováno v:
Biology of Sex Differences, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a key player of lipid metabolism with higher plasma levels in women throughout their life. Statin treatment affects PCSK9 levels also showing evidence of sex-differential ef
Externí odkaz:
https://doaj.org/article/52974b7065a44f87b840e07239a4601b
Autor:
Simon B. Leininger, Stephan T. Staudner, Manuel J. Vogel, Julian Mustroph, Ute Hubauer, Stefan Wallner, Petra Lehn, Ralph Burkhardt, Christine Meindl, Frank Hanses, Markus Zimmermann, Lars S. Maier, Julian Hupf, Carsten G. Jungbauer
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-11 (2024)
Background The aim of this study was to investigate whether bioactive adrenomedullin (bio-ADM) and interleukin-6 (IL-6) are related to acute kidney injury (AKI) and severe illness in COVID-19 patients. Methods 153 patients with COVID-19 admitted to t
Externí odkaz:
https://doaj.org/article/6c3d29b440d64cb8a3a0e05653b36d3f
Autor:
Markus Scholz, Katrin Horn, Janne Pott, Matthias Wuttke, Andreas Kühnapfel, M. Kamal Nasr, Holger Kirsten, Yong Li, Anselm Hoppmann, Mathias Gorski, Sahar Ghasemi, Man Li, Adrienne Tin, Jin-Fang Chai, Massimiliano Cocca, Judy Wang, Teresa Nutile, Masato Akiyama, Bjørn Olav Åsvold, Nisha Bansal, Mary L. Biggs, Thibaud Boutin, Hermann Brenner, Ben Brumpton, Ralph Burkhardt, Jianwen Cai, Archie Campbell, Harry Campbell, John Chalmers, Daniel I. Chasman, Miao Ling Chee, Miao Li Chee, Xu Chen, Ching-Yu Cheng, Renata Cifkova, Martha Daviglus, Graciela Delgado, Katalin Dittrich, Todd L. Edwards, Karlhans Endlich, J. Michael Gaziano, Ayush Giri, Franco Giulianini, Scott D. Gordon, Daniel F. Gudbjartsson, Stein Hallan, Pavel Hamet, Catharina A. Hartman, Caroline Hayward, Iris M. Heid, Jacklyn N. Hellwege, Bernd Holleczek, Hilma Holm, Nina Hutri-Kähönen, Kristian Hveem, Berend Isermann, Jost B. Jonas, Peter K. Joshi, Yoichiro Kamatani, Masahiro Kanai, Mika Kastarinen, Chiea Chuen Khor, Wieland Kiess, Marcus E. Kleber, Antje Körner, Peter Kovacs, Alena Krajcoviechova, Holly Kramer, Bernhard K. Krämer, Mikko Kuokkanen, Mika Kähönen, Leslie A. Lange, James P. Lash, Terho Lehtimäki, Hengtong Li, Bridget M. Lin, Jianjun Liu, Markus Loeffler, Leo-Pekka Lyytikäinen, Patrik K. E. Magnusson, Nicholas G. Martin, Koichi Matsuda, Yuri Milaneschi, Pashupati P. Mishra, Nina Mononen, Grant W. Montgomery, Dennis O. Mook-Kanamori, Josyf C. Mychaleckyj, Winfried März, Matthias Nauck, Kjell Nikus, Ilja M. Nolte, Raymond Noordam, Yukinori Okada, Isleifur Olafsson, Albertine J. Oldehinkel, Brenda W. J. H. Penninx, Markus Perola, Nicola Pirastu, Ozren Polasek, David J. Porteous, Tanja Poulain, Bruce M. Psaty, Ton J. Rabelink, Laura M. Raffield, Olli T. Raitakari, Humaira Rasheed, Dermot F. Reilly, Kenneth M. Rice, Anne Richmond, Paul M. Ridker, Jerome I. Rotter, Igor Rudan, Charumathi Sabanayagam, Veikko Salomaa, Neil Schneiderman, Ben Schöttker, Mario Sims, Harold Snieder, Klaus J. Stark, Kari Stefansson, Hannah Stocker, Michael Stumvoll, Patrick Sulem, Gardar Sveinbjornsson, Per O. Svensson, E-Shyong Tai, Kent D. Taylor, Bamidele O. Tayo, Andrej Teren, Yih-Chung Tham, Joachim Thiery, Chris H. L. Thio, Laurent F. Thomas, Johanne Tremblay, Anke Tönjes, Peter J. van der Most, Veronique Vitart, Uwe Völker, Ya Xing Wang, Chaolong Wang, Wen Bin Wei, John B. Whitfield, Sarah H. Wild, James F. Wilson, Thomas W. Winkler, Tien-Yin Wong, Mark Woodward, Xueling Sim, Audrey Y. Chu, Mary F. Feitosa, Unnur Thorsteinsdottir, Adriana M. Hung, Alexander Teumer, Nora Franceschini, Afshin Parsa, Anna Köttgen, Pascal Schlosser, Cristian Pattaro
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract X-chromosomal genetic variants are understudied but can yield valuable insights into sexually dimorphic human traits and diseases. We performed a sex-stratified cross-ancestry X-chromosome-wide association meta-analysis of seven kidney-relat
Externí odkaz:
https://doaj.org/article/268d127148904565be810f5bb7b9bb96
Autor:
Annina Nickel, Christina Blücher, Omeir Kadri, Nancy Schwagarus, Silvana Müller, Michael Schaab, Joachim Thiery, Ralph Burkhardt, Sonja C. Stadler
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/77f4718f00394250b3eac3e2dace2e6d
Autor:
Manuel Julian Vogel, Simon B Leininger, Stephan T Staudner, Ute Hubauer, Stefan Wallner, Julian Mustroph, Frank Hanses, Markus Zimmermann, Petra Lehn, Ralph Burkhardt, Lars S Maier, Julian Hupf, Carsten G Jungbauer
Publikováno v:
Kidney & Blood Pressure Research, Vol 48, Iss 1, Pp 424-435 (2023)
Introduction: The ongoing COVID-19 pandemic is placing an extraordinary burden on our health care system with its limited resources. Accurate triage of patients is necessary to ensure medical care for those most severely affected. In this regard, bio
Externí odkaz:
https://doaj.org/article/4429c5764d084d199e5b3974188be022
Autor:
Janina M. Herold, Jana Nano, Mathias Gorski, Thomas W. Winkler, Kira J. Stanzick, Martina E. Zimmermann, Caroline Brandl, Annette Peters, Wolfgang Koenig, Ralph Burkhardt, André Gessner, Iris M. Heid, Christian Gieger, Klaus J. Stark
Publikováno v:
BMC Genomic Data, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Polygenic scores (PGSs) combining genetic variants found to be associated with creatinine-based estimated glomerular filtration rate (eGFRcrea) have been applied in various study populations with different age ranges. This has sho
Externí odkaz:
https://doaj.org/article/fa22513729e64e08aa82db89613d0f60
Autor:
Susanne Heimerl, Marcus Höring, Dominik Kopczynski, Alexander Sigruener, Christina Hart, Ralph Burkhardt, Anne Black, Robert Ahrends, Gerhard Liebisch
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Lipids play a central role in platelet physiology. Changes in the lipidome have already been described for basal and activated platelets. However, quantitative lipidomic data of platelet activation, including the released complex lipids, are
Externí odkaz:
https://doaj.org/article/3203d4903e8e4865ae3716ca28701982
Autor:
David Peterhoff, Simon Wiegrebe, Sebastian Einhauser, Arisha J. Patt, Stephanie Beileke, Felix Günther, Philipp Steininger, Hans H. Niller, Ralph Burkhardt, Helmut Küchenhoff, Olaf Gefeller, Klaus Überla, Iris M. Heid, Ralf Wagner
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
SARS-CoV-2 antibody quantity and quality are key markers of humoral immunity. However, there is substantial uncertainty about their durability. We investigated levels and temporal change of SARS-CoV-2 antibody quantity and quality. We analyzed sera (
Externí odkaz:
https://doaj.org/article/9527678d20b44a4db0bce5077cc7d4ee
Autor:
Lucia Scheidler, Katrin Hippe, Sakhila Ghimire, Daniela Weber, Markus Weber, Elisabeth Meedt, Petra Hoffmann, Petra Lehn, Ralph Burkhardt, Andreas Mamilos, Matthias Edinger, Daniel Wolff, Hendrik Poeck, Matthias Evert, Andre Gessner, Wolfgang Herr, Ernst Holler
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Intestinal immunoglobulin A (IgA) is strongly involved in microbiota homeostasis. Since microbiota disruption is a major risk factor of acute graft-versus-host disease (GvHD), we addressed the kinetics of intestinal IgA-positive (IgA+) plasma cells b
Externí odkaz:
https://doaj.org/article/8f1272643dd64c11be40b69110048012
Autor:
Inka Rapöhn, Ivet Elias, Juliane Weiner, Anna Pujol, Stephanie Kehr, Alexandra Chadt, Hadi Al-Hasani, Ralph Burkhardt, Nora Klöting, Michael Stumvoll, Fatima Bosch, Peter Kovacs, John T. Heiker, Jana Breitfeld
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Adipose tissue inflammation and insulin resistance are hallmarks in the development of metabolic diseases resulting from overweight and obesity, such as type 2 diabetes and non-alcoholic fatty liver disease. In obesity, adipocytes predominantly secre
Externí odkaz:
https://doaj.org/article/f7e50b71dc074a71be474ae2dec1aff1