Výsledky vyhledávání - "Ralf Wischnat"

An Aza Analogue of iso-Levoglucosenone: Synthesis and Application of a New Building Block for Imino Sugars

Autor: Hans-Josef Altenbach, David J. Brauer, Ralf Wischnat, Jens Ostrowski

Publikováno v: European Journal of Organic Chemistry. 2003:1104-1110

The aza analogue 3 of iso-levoglucosenone, which is easily accessible from furylglycine, was used as a flexible building block for the synthesis of various imino sugars. Enantiomerically pure products are available starting from optically active fury

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::60c0e687c5e7fd80b452b0ac8cac3ff2
https://doi.org/10.1002/ejoc.200390163

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Programmable One-Pot Oligosaccharide Synthesis

Autor: Zhiyuan Zhang, Ian R. Ollmann, Xin-Shan Ye, Ralf Wischnat, Timor Baasov, Chi-Huey Wong

Publikováno v: Journal of the American Chemical Society. 121:734-753

The reactivity of a number of p-methylphenyl thioglycoside (STol) donors which are either fully protected or have one hydroxyl group exposed has been quantitatively determined by HPLC in conjunction with the development of a broadly applicable approa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b00018fdd395679a516749c37b9ec20
https://doi.org/10.1021/ja982232s

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Synthesis of a New Class of N-Linked Lewis and LacNAc Analogues as Potential Inhibitors of Human Fucosyltransferases: A General Method for the Incorporation of an Iminocyclitol as a Transition-State Mimetic of the Donor Sugar to the Acceptor

Autor: Richard Martin, Ralf Wischnat, Chi-Huey Wong

Publikováno v: The Journal of Organic Chemistry. 63:8361-8365

A short and effective synthesis of N-linked di- and trisaccharides is described. In a high-yielding reaction sequence, the glucosamine derivative 1 was transformed to the 3-azido-2,3-dideoxy sugar ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::887292f3618f2a59915c35b4eddd2db2
https://doi.org/10.1021/jo981245l

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Highly Efficient Chiral-Pool Synthesis of (2S,4R)-4-Hydroxyornithine

Autor: Ralf Wischnat, Joachim Rudolph, Frithjof Hannig, and Heidi Theis

Publikováno v: Organic Letters. 3:3153-3155

[reaction: see text] A concise synthesis of the amino acid (2S,4R)-4-hydroxyornithine is described. Starting from diprotected L-aspartic acid, the scaffold of the target compound is constructed in a three-step approach: an efficient alpha-nitroketone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbde5da47bf544669fea7fae232b4bf9
https://doi.org/10.1021/ol016445p

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ChemInform Abstract: Synthesis of a 2-Hydroxymethyl-dihydropyridone System as a Flexible Building Block for the Preparation of Azasugars

Autor: Hans-Josef Altenbach, Ralf Wischnat

Publikováno v: ChemInform. 26

m CPBA induced oxidative cyclization of the aminoalcohol 1a under complete stereocontrol, generating after acetal formation a new diastereomerically pure key intermediate 2b for the flexible synthesis of azasugars. 2b could be converted to protected

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41fa8a7f7d4055db1a810a417da71994
https://doi.org/10.1002/chin.199542148

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