Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ralf Weisshorn"'
Publikováno v:
ains · Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie. 39:147-152
Objective: Theophylline, a methylxanthine, leads to an increase of the cytoplasmic Ca 2 + -concentration in the muscle cell. Since the in-vitro contracture test (IVCT) with halothane and caffeine does not distinguish a 100% between malignant hyperthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0295d7d3c828506a1cf59f4326705d29
https://doi.org/10.1055/s-2004-814328
https://doi.org/10.1055/s-2004-814328
Autor:
Frank Wappler, Jochen Schulte am Esch, M. U. Gerbershagen, Marko Fiege, Melanie Menge, Ralf Weisshorn
Publikováno v:
Anesthesiology. 99:1132-1136
Background 3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") can mediate acute toxic effects such as muscle rigidity, metabolic acidosis, and hyperthermia. Because of close clinical similarities, an association between MDMA intoxication and maligna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa845d082ff29a7bed6a8a042b730f6c
https://doi.org/10.1097/00000542-200311000-00020
https://doi.org/10.1097/00000542-200311000-00020
Autor:
S. Doetsch, Marko Fiege, Frank Lehmann-Horn, Werner Klingler, R. Fricker, K. Censier, Y Nivoche, J. Schulte am Esch, I. Tzanova, James J. A. Heffron, Vincenzo Tegazzin, Martin Anetseder, Albert Urwyler, Philip M. Hopkins, E. Hartung, P. Felleiter, P.J. Halsall, L. Heytens, C. P. Baur, Frank Wappler, Ralf Weisshorn
Publikováno v:
European journal of anaesthesiology
Background and objective The in vitro contracture test with halothane and caffeine is the gold standard for the diagnosis of susceptibility to malignant hyperthermia (MH). However, the sensitivity of the in vitro contracture test is between 97 and 99
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abba398ed20b1021a705ba0c1aa04197
https://doi.org/10.1097/00003643-200307000-00003
https://doi.org/10.1097/00003643-200307000-00003
Autor:
Marko Fiege, Jochen Schulte am Esch, Kerstin Kolodzie, M. U. Gerbershagen, Ralf Weisshorn, Frank Wappler
Publikováno v:
Anesthesiology. 98:944-949
Background In human skeletal muscles, the phosphodiesterase-III inhibitor enoximone induces in vitro contracture development, and it has been suggested that enoximone could trigger malignant hyperthermia (MH). In this study, the in vitro and in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c2f5d572352e9e15396fda181fb921
https://doi.org/10.1097/00000542-200304000-00022
https://doi.org/10.1097/00000542-200304000-00022
Autor:
Markus Steinfath, Ralf Weisshorn, M. U. Gerbershagen, Jochen Schulte am Esch, Marko Fiege, Frank Wappler
Publikováno v:
Anesthesiology. 97:345-350
Background More than 20 mutations in the gene encoding for the ryanodine receptor (RYR1), a Ca2+ release channel of the skeletal muscle sarcoplasmic reticulum, have been found to be associated with malignant hyperthermia (MH). This study was designed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8f3b7f418474befacce5f8758b5171
https://doi.org/10.1097/00000542-200208000-00010
https://doi.org/10.1097/00000542-200208000-00010
Publikováno v:
AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie. 37:138-143
Objective: The abuse of cocaine can cause serious medical complications like tachycardia, rhabdomyolysis, and hyperthermia. Because of the clinical similarities, it has been suggested that cocaine might be a trigger of malignant hyperthermia (MH). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95f568e0eb1968d6245156ca423f32de
https://doi.org/10.1055/s-2002-21806
https://doi.org/10.1055/s-2002-21806
Autor:
Marko Fiege, Jochen Schulte am Esch, Kerstin Kolodzie, Frank Wappler, M. U. Gerbershagen, Ralf Weißhorn
Publikováno v:
Anesthesiology. 101:1475-1477
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb6826164b7ba843a84fcc705a82e79c
https://doi.org/10.1097/00000542-200412000-00033
https://doi.org/10.1097/00000542-200412000-00033
Publikováno v:
Journal of Biomedicine and Biotechnology, Vol 2011 (2011)
Journal of Biomedicine and Biotechnology
Journal of Biomedicine and Biotechnology
Background. Theophylline was shown to induce contracture development in porcine malignant hyperthermia (MH) susceptible (MHS) skeletal muscles in vitro. The purpose of the current study was to investigate the in vivo effects of theophylline in MHS an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a109258b338a40ac6960cdc747aa22
https://doaj.org/article/34257d340897442686ccf1c319ac3dd5
https://doaj.org/article/34257d340897442686ccf1c319ac3dd5
Publikováno v:
Journal of Anesthesia & Clinical Research.
Background: Ten case reports have described clinical signs and symptoms of malignant hyperthermia (MH) that developed following local anaesthetics. In this study, the In-Vitro effects of dibucaine, an amide local anaesthetic, were compared in skeleta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ccd45da51c031dbc3aeb7c2874ba7f2
https://doi.org/10.4172/2155-6148.1000172
https://doi.org/10.4172/2155-6148.1000172
Autor:
Marko Fiege, Niels Bleese, Ralf Weißhorn, Friedrich-Christian Riess, Frank Wappler, Heinz Bergmann, Sina Moshar, Joachim Kormann
Publikováno v:
Anesthesiology. 94:355-357
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c758060f352f14bc50a53bac40967553
https://doi.org/10.1097/00000542-200102000-00029
https://doi.org/10.1097/00000542-200102000-00029