Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ralf Strasser"'
Autor:
Clemens Schulte, Alice Soldà, Sebastian Spänig, Nathan Adams, Ivana Bekić, Werner Streicher, Dominik Heider, Ralf Strasser, Hans Michael Maric
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Fluorescence proximity sensing enables high throughput determination of binding affinities and kinetics of peptide inhibitors with varying valency and multivalent architecture.
Externí odkaz:
https://doaj.org/article/8429778c1c484c93995699e093705efa
Autor:
Ralf Strasser, Friederike M. Möller, Dóra Balogh, Stephan A. Sieber, Hendrik Dietz, Eva Bertosin, Markus Lakemeyer
Publikováno v:
Angewandte Chemie International Edition. 58:7127-7132
The proteolytic complex ClpXP is fundamental to bacterial homeostasis and pathogenesis. Because of its conformational flexibility, the development of potent ClpXP inhibitors is challenging, and novel tools to decipher its intricate regulation are urg
Autor:
Eva Bertosin, Stephan A. Sieber, Hendrik Dietz, Friederike M. Möller, Dóra Balogh, Markus Lakemeyer, Ralf Strasser
Publikováno v:
Angewandte Chemie. 131:7201-7206
Publikováno v:
Langmuir. 34:14796-14801
The characterization of novel therapeutic antibodies with multivalent or multispecific binding sites requires new measurement modalities for biosensors, to discriminate the engagement of antigens via one, two, or even more binding moieties. The prese
Autor:
Erika Isono, Christian Wunschel, Ralf Strasser, Katrin Franz-Oberdorf, Andreas Langer, Wilfried Schwab, Quirin L. Ranftl
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 85:1891-1901
The strawberry fruit allergens Fra a 1.01E, Fra a 1.02 and Fra a 1.03 belong to the group of pathogenesis-related 10 (PR-10) proteins and are homologs of the major birch pollen Bet v 1 and apple allergen Mal d 1. Bet v 1 related proteins are the most
Autor:
Ralf Strasser, Bastian Groitl, Gergely B. Cserép, Péter Kele, Ulrike Reisacher, Hans-Achim Wagenknecht
Publikováno v:
Bioconjugate chemistry. 30(6)
6-Ethynyl-1,2,4-triazine is a small bioorthogonally reactive group we applied for fluorescent labeling of oligonucleotides by Diels-Alder reactions with inverse electron demand. We synthetically attached this functional group to the 7-position of 7-d
Publikováno v:
Chembiochem : a European journal of chemical biology. 19(18)
A deoxyadenosine triphosphate (dATP) analogue for DNA labeling was synthesized with the 1-methylcyclopropene (1MCP) group at the 7-position of 7-deaza-2'-deoxyadenosine and applied for primer extension experiments. The real-time kinetic data reveals
Autor:
Katrin, Franz-Oberdorf, Andreas, Langer, Ralf, Strasser, Erika, Isono, Quirin L, Ranftl, Christian, Wunschel, Wilfried, Schwab
Publikováno v:
Proteins. 85(10)
The strawberry fruit allergens Fra a 1.01E, Fra a 1.02 and Fra a 1.03 belong to the group of pathogenesis-related 10 (PR-10) proteins and are homologs of the major birch pollen Bet v 1 and apple allergen Mal d 1. Bet v 1 related proteins are the most
Autor:
Keyarash Sadeghian, Malte Winnacker, Dimitrios Stathis, Ralf Strasser, Sabine Schneider, Christian Ochsenfeld, Thomas Carell, Denis Flaig, Iris D. Blank
Publikováno v:
Angewandte Chemie. 126:10208-10212
Living organisms protect the genome against external influences by recognizing and repairing damaged DNA. A common source of gene mutation is the oxidized guanine, which undergoes base excision repair through cleavage of the glycosidic bond between t
Publikováno v:
Journal of the American Chemical Society. 134:15225-15228
A label-free method for the analysis of interactions of proteins with surface-tethered ligands is introduced. Short DNA levers are electrically actuated on microelectrodes by ac potentials, and their switching dynamics are measured in real-time by fl