Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Ralf Stohwasser"'
1
LEDGF/p75 Is Required for an Efficient DNA Damage Response
Autor: Peter Schierack, Romano Weiss, Victoria Liedtke, Ralf Stohwasser, Stefan Rödiger, Lysann Schenk, Christian Schröder, Dirk Roggenbuck
Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 5866, p 5866 (2021)
BackgroundLens epithelium derived growth factor splice variant of 75 kDa (LEDGF/p75), is overexpressed in different solid cancers and cancer cell lines and various autoinflammatory diseases. Due to its ability to bind chromatin, it acts as a transcri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a60d979ecf4539f0152463b1eb8a461
Zobrazit plný text záznamu
4
Open source bioimage informatics tools for the analysis of DNA damage and associated biomarkers
Autor: Jens Schneider, Stefan Rödiger, Dirk Roggenbuck, Tobias Jung, Ralf Stohwasser, Madeleine Ruhe, Romano Weiss, Peter Schierack
Publikováno v: Journal of Laboratory and Precision Medicine. :21-21
DNA double-strand breaks (DSBs) are critical cellular lesions that represent a high risk for genetic instability. DSBs initiate repair mechanisms by recruiting sensor proteins and mediators. DSB biomarkers, like phosphorylated histone 2AX (γH2AX) an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::409736db9f59f5f1febe5d4201e31372
https://doi.org/10.21037/jlpm.2019.04.05
Zobrazit plný text záznamu
5
Multiplex localization of sequential peptide epitopes by use of a planar microbead chip
Autor: Carsten Schmidt, Anja Moncsek, Melanie Gruner, Stefan Rödiger, Peter Schierack, Katja Hanack, Christian Schröder, Ralf Stohwasser
Epitope mapping is crucial for the characterization of protein-specific antibodies. Commonly, small overlapping peptides are chemically synthesized and immobilized to determine the specific peptide sequence. In this study, we report the use of a fast
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d717488056751e98d8e32d3de863c7
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/45607
Zobrazit plný text záznamu
6
Evidence for anti-apoptotic roles of proteasome activator 28γ via inhibiting caspase activity
Autor: Peter-Michael Kloetzel, Andrea Lehmann, Hannes Meyer, Ralf Stohwasser, Anja Moncsek, Melanie Gruner
Publikováno v: Apoptosis : an international journal on programmed cell death. 20(9)
Proteasome activator PA28γ (REGγ, Ki antigen) has recently been demonstrated to display anti-apoptotic properties via enhancing Mdm2-p53 interaction, thereby facilitating ubiquitination and down-regulation of the tumor suppressor p53. In this study
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106806f45543f264122c4876c99bd448
https://pubmed.ncbi.nlm.nih.gov/26201457
Zobrazit plný text záznamu
7
Kinetic evidences for facilitation of peptide channelling by the proteasome activator PA28
Autor: Ulrike Salzmann, Ralf Stohwasser, Jan Giesebrecht, Hermann-Georg Holzhütter, Peter-Michael Kloetzel
Publikováno v: European Journal of Biochemistry. 267:6221-6230
The activation kinetics of constitutive and IFNgamma-stimulated 20S proteasomes obtained with homomeric (recPA28alpha, recPA28beta) and heteromeric (recPA28alphabeta) forms of recombinant 11S regulator PA28 was analysed by means of kinetic modelling.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1f45d7c5eb525d6f25103c9d3a0d7f4
https://doi.org/10.1046/j.1432-1327.2000.01706.x
Zobrazit plný text záznamu
8
Biochemical analysis of proteasomes from mouse microglia: Induction of immunoproteasomes by interferon-? and lipopolysaccharide
Autor: Helmut Kettenmann, Peter-M. Kloetzel, Regine Kraft, Uwe-Karsten Hanisch, Ralf Stohwasser, Eva-Christina Müller, Jan Giesebrecht, Karl Georg Häusler
Publikováno v: Glia. 29:355-365
The 20S proteasome is a multicatalytic threonine protease and serves to process peptides that are subsequently presented as antigenic epitopes by MHC class I molecules. In the brain, microglial cells are the major antigen presenting cells and they re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27ae15008394dd6c448dc9227859498b
https://doi.org/10.1002/(sici)1098-1136(20000215)29:4<355::aid-glia6>3.0.co
Zobrazit plný text záznamu
9
PA28αβ double and PA28β single transfectant mouse B8 cell lines reveal enhanced presentation of a mouse cytomegalovirus (MCMV) pp89 MHC class I epitope
Autor: Ulrich H. Koszinowski, Ralf Stohwasser, Andrea Soza, Maren Eggers, Peter-M. Kloetzel
Publikováno v: Molecular Immunology. 37:13-19
PA28 is an interferon-gamma inducible modulator of proteasome function composed of two subunits, i.e. PA28alpha and PA28beta. Previously we showed that stabile overexpression of the PA28alpha subunit alone supported MHC class I antigen presentation o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae53ace861ed520dcf62529b178b7f6
https://doi.org/10.1016/s0161-5890(00)00017-1
Zobrazit plný text záznamu
10
Molecular cloning of the mouse proteasome subunits MC14 and MECL-1: reciprocally regulated tissue expression of interferon-γ-modulated proteasome subunits
Autor: Sybille Standera, Marcus Groettrup, Inga Peters, Peter-M. Kloetzel, Ralf Stohwasser
Publikováno v: European Journal of Immunology. 27:1182-1187
The primary structures of the interferon-gamma-inducible mouse 20S proteasome subunit MECL-1 and its alternate homolog MC14 were determined. Northern analysis of mouse tissues revealed that MECL-1 mRNA predominantly occurred in thymus, lymph nodes, a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777ca79d1463102b65af706d02d49182
https://doi.org/10.1002/eji.1830270520
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje