Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ralf Siegner"'
Autor:
Cassandra Falckenhayn, Agata Bienkowska, Jörn Söhle, Katrin Wegner, Guenter Raddatz, Boris Kristof, Dirk Kuck, Ralf Siegner, Ronny Kaufmann, Julia Korn, Sascha Baumann, Daniela Lange, Andreas Schepky, Henry Völzke, Lars Kaderali, Marc Winnefeld, Frank Lyko, Elke Grönniger
Publikováno v:
Frontiers in Aging, Vol 4 (2024)
Changes in DNA methylation patterning have been reported to be a key hallmark of aged human skin. The altered DNA methylation patterns are correlated with deregulated gene expression and impaired tissue functionality, leading to the well-known skin a
Externí odkaz:
https://doaj.org/article/41b18a4c3c734ca79c31cb048d5cc259
Autor:
Nicholas Holzscheck, Cassandra Falckenhayn, Jörn Söhle, Boris Kristof, Ralf Siegner, André Werner, Janka Schössow, Clemens Jürgens, Henry Völzke, Horst Wenck, Marc Winnefeld, Elke Grönniger, Lars Kaderali
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract The development of ‘age clocks’, machine learning models predicting age from biological data, has been a major milestone in the search for reliable markers of biological age and has since become an invaluable tool in aging research. Howe
Externí odkaz:
https://doaj.org/article/777c395850e541569fc03b8d41e94be4
Autor:
Horst Wenck, Franz Stäb, Jörn Söhle, Marc Winnefeld, Bodo Brückner, Christoph Smuda, Elke Grönniger, Ludger Kolbe, Ralf Siegner, Simone Brönneke
Publikováno v:
Angiogenesis. 18:361-371
Wound healing is a multistage process involving collaborative efforts of different cell types and distinct cellular functions. Among others, the high metabolic activity at the wound site requires the formation and sprouting of new blood vessels (angi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e0d734aa8cbdad5e4025696c43e635
https://doi.org/10.1007/s10456-015-9472-7
https://doi.org/10.1007/s10456-015-9472-7
Autor:
Heiko Mielke, Christoph Smuda, Gabi Sperling, Sven Fey, Andrea Krüger, Anja Knott, Thorsten Burkhardt, Helge Schwengler, Andreas Berroth, Volker Dr. Achterberg, Marc Winnefeld, Alexandra Vogelsang, Mojgan Behtash, Tanya Eisenberg, Janosch Hildebrand, Katja Dunckelmann, Frank Teuber, Heike Diekmann, Janne Möbius, Sonja Kristof, Thomas Blatt, Dana Retzer, Juliane Lüttke, Ralf Siegner
Publikováno v:
Biofactors (Oxford, England)
Ubiquinone (coenzyme Q10, Q10) represents an endogenously synthesized lipid‐soluble antioxidant which is crucial for cellular energy production but is diminished with age and under the influence of external stress factors in human skin. Here, it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86e2390f2c8c650c62d8f0f7f12effe
https://pubmed.ncbi.nlm.nih.gov/26648450
https://pubmed.ncbi.nlm.nih.gov/26648450
Autor:
Marc Winnefeld, Ursula Holtzmann, Franz Stäb, Ralf Siegner, Horst Wenck, Thomas Raschke, Stefan Heuser, Andreas Schepky, Jörn Söhle
Publikováno v:
Nutrition & Metabolism
Nutrition & Metabolism, Vol 7, Iss 1, p 66 (2010)
Nutrition & Metabolism, Vol 7, Iss 1, p 66 (2010)
Background The cellular and molecular mechanisms of adipose tissue biology have been studied extensively over the last two decades. Adipose tissue growth involves both an increase in fat cell size and the formation of mature adipocytes from precursor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52c6c0c51e8e42265ad90ec208d7a18
https://doi.org/10.1186/1743-7075-7-66
https://doi.org/10.1186/1743-7075-7-66
Autor:
Andreas Schepky, Franz Stäb, Horst Wenck, Elke Grönniger, Anja Knott, Marc Winnefeld, Ralf Siegner, Jörn Söhle, Ursula Holtzmann, Stefan Gallinat
Publikováno v:
Nutrition & Metabolism
Nutrition & Metabolism, Vol 6, Iss 1, p 20 (2009)
Nutrition & Metabolism, Vol 6, Iss 1, p 20 (2009)
BackgroundThe dramatic increase in obesity-related diseases emphasizes the need to elucidate the cellular and molecular mechanisms underlying fat metabolism. To investigate how natural substances influence lipolysis and adipogenesis, we determined th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23144408c4902256c0fe55085eda29f
https://pubmed.ncbi.nlm.nih.gov/19409077
https://pubmed.ncbi.nlm.nih.gov/19409077
Autor:
Andreas Schepky, Horst Wenck, S. S. Biel, Klaus-Peter Wittern, S. Zirpins, Robert Dr. Schmucker, Ralf Siegner, Ursula Holtzmann
Publikováno v:
International journal of cosmetic science. 26(5)
Desquamation in human skin is a well-balanced process of de novo production of corneocytes and their shedding from the skin surface. The proteolysis of corneodesmosomes is an important step in the final desquamation process. In the degradation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0140758d4e3ef0402663f92c666e665b
https://pubmed.ncbi.nlm.nih.gov/18492137
https://pubmed.ncbi.nlm.nih.gov/18492137