Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ralf Pflanz"'
Autor:
Wai Tuck Soh, Hanna P. Roetschke, John A. Cormican, Bei Fang Teo, Nyet Cheng Chiam, Monika Raabe, Ralf Pflanz, Fabian Henneberg, Stefan Becker, Ashwin Chari, Haiyan Liu, Henning Urlaub, Juliane Liepe, Michele Mishto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract If and how proteasomes catalyze not only peptide hydrolysis but also peptide splicing is an open question that has divided the scientific community. The debate has so far been based on immunopeptidomics, in vitro digestions of synthetic poly
Externí odkaz:
https://doaj.org/article/b17003d64f9544af818720977eafb74a
Autor:
Leonard Drees, Tatiana Königsmann, Martin H J Jaspers, Ralf Pflanz, Dietmar Riedel, Reinhard Schuh
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007882 (2019)
Extracellular matrix (ECM) assembly and remodelling is critical during development and organ morphogenesis. Dysregulation of ECM is implicated in many pathogenic conditions, including cancer. The type II transmembrane serine protease matriptase and t
Externí odkaz:
https://doaj.org/article/b301564d8f4c4230b783fef3fe0428d0
Autor:
Ben Harder, Adrian Schomburg, Ralf Pflanz, Katharina M. Küstner, Nina Gerlach, Reinhard Schuh
Publikováno v:
BioTechniques, Vol 44, Iss 6, Pp 765-772 (2008)
Drosophila provides a powerful experimental system to analyze gene functions in a multi-cellular organism. Here we describe an in vivo method that interferes with the integrity of selected proteins through site-specific cleavage in Drosophila. The te
Externí odkaz:
https://doaj.org/article/e3a93871634b4a45b485274f7c313974
Publikováno v:
Open Biology, Vol 5, Iss 1 (2015)
Tao-1, the single representative of the Sterile 20 kinase subfamily in Drosophila, is best known for destabilizing microtubules at the actin-rich cortex, regulating the cytoskeletal architecture of cells. More recently, Tao-1 was shown to act in the
Externí odkaz:
https://doaj.org/article/09b6be22eeff47b99123b4bb72b5c548
Autor:
Bettina Homberg, Piotr Neumann, Markus Deckers, Iwan Parfentev, Henning Urlaub, Peter Rehling, Ralf Pflanz, Ralf Ficner, Andreas Linden
Publikováno v:
Molecular and Cellular Proteomics
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics : MCP
Protein interactions in mitochondria isolated from S. cerevisiae grown on glycerol or glucose medium were analyzed by XL-MS. The non-cleavable cross-linker BS3 proved suitable for elucidating differences in protein-protein interactions under both con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92e791754840510ba595958dd2d3b9a
https://doi.org/10.1074/mcp.ra120.002028
https://doi.org/10.1074/mcp.ra120.002028
Autor:
Reinhard Schuh, Leonard Drees, Dietmar Riedel, Martin H. J. Jaspers, Ralf Pflanz, Tatiana Königsmann
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007882 (2019)
PLoS Genetics
PLoS Genetics
Extracellular matrix (ECM) assembly and remodelling is critical during development and organ morphogenesis. Dysregulation of ECM is implicated in many pathogenic conditions, including cancer. The type II transmembrane serine protease matriptase and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d4cb9d5a46bd58a80496c24ed94cb6
https://doi.org/10.1371/journal.pgen.1007882
https://doi.org/10.1371/journal.pgen.1007882
Autor:
Reinhard Schuh, Ben Harder, Adrian Schomburg, Nina Gerlach, Katharina M. Küstner, Ralf Pflanz
Publikováno v:
BioTechniques. 44:765-772
Drosophila provides a powerful experimental system to analyze gene functions in a multi-cellular organism. Here we describe an in vivo method that interferes with the integrity of selected proteins through site-specific cleavage in Drosophila. The te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c68b88a4ca8642534de82155b7329b5
https://doi.org/10.2144/000112884
https://doi.org/10.2144/000112884
Autor:
Tobias M. Rasse, Sarah Lenz, Shabab B. Hannan, Aaron Voigt, Malte Butzlaff, Josephine Ng, Hannes Voßfeldt, Jörg B. Schulz, Ralf Pflanz, Peter Karsten, Katja Prüßing
Publikováno v:
Human molecular genetics 24(13), 3623-3637 (2015). doi:10.1093/hmg/ddv107
Human Molecular Genetics
Human Molecular Genetics
The gene mapt codes for the microtubule-associated protein Tau. The R406W amino acid substitution in Tau is associated with frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17) characterized by Tau-positive filamentous inclusio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3245fe000d9d678bd7fdd090d76eec05
https://pubmed.ncbi.nlm.nih.gov/25794683
https://pubmed.ncbi.nlm.nih.gov/25794683
Publikováno v:
Developmental Dynamics. 224:403-412
Drosophila neuroblasts act as stem cells. Their proliferation is controlled through cell cycle arrest and activation in a spatiotemporal pattern. Several genes have been identified that control the pattern of neuroblast quiescence and proliferation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::965fcf49ad0d37ee9227db3ec8cf7cc8
https://doi.org/10.1002/dvdy.10120
https://doi.org/10.1002/dvdy.10120
Autor:
Martin H. J. Jaspers, Reinhard Schuh, Steffen Kawelke, Ralf Pflanz, Ivo Feussner, Dietmar Riedel
Publikováno v:
Developmental Biology
The transition from a liquid to a gas filled tubular network is the prerequisite for normal function of vertebrate lungs and invertebrate tracheal systems. However, the mechanisms underlying the process of gas filling remain obscure. Here we show tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87639af488a79ec97f821656bb48b71
https://pubmed.ncbi.nlm.nih.gov/24183938
https://pubmed.ncbi.nlm.nih.gov/24183938