Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ralf Nilsson"'
Autor:
Kai Liu, Ralf Nilsson, Elisa Lázaro-Ibáñez, Hanna Duàn, Tasso Miliotis, Marie Strimfors, Michael Lerche, Ana Rita Salgado Ribeiro, Johan Ulander, Daniel Lindén, Anna Salvati, Alan Sabirsh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract In terms of lipid nanoparticle (LNP) engineering, the relationship between particle composition, delivery efficacy, and the composition of the biocoronas that form around LNPs, is poorly understood. To explore this we analyze naturally effic
Externí odkaz:
https://doaj.org/article/41ddf1ba8b124addb8c13982c9688b78
Autor:
Kasparas Petkevicius, Henrik Palmgren, Matthew S. Glover, Andrea Ahnmark, Anne-Christine Andréasson, Katja Madeyski-Bengtson, Hiroki Kawana, Erik L. Allman, Delaney Kaper, Martin Uhrbom, Liselotte Andersson, Leif Aasehaug, Johan Forsström, Simonetta Wallin, Ingela Ahlstedt, Renata Leke, Daniel Karlsson, Hernán González-King, Lars Löfgren, Ralf Nilsson, Giovanni Pellegrini, Nozomu Kono, Junken Aoki, Sonja Hess, Grzegorz Sienski, Marc Pilon, Mohammad Bohlooly-Y, Marcello Maresca, Xiao-Rong Peng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The regulation of cellular phosphatidylethanolamine (PE) acyl chain composition is poorly understood. Here, the authors show that TLCD1 and TLCD2 proteins mediate the formation of monounsaturated fatty acid-containing PE species and promote the progr
Externí odkaz:
https://doaj.org/article/15464563b39b4d54986a8c040d9d92b8
Autor:
Elsbet J. Pieterman, Hans M. G. Princen, Annica Jarke, Ralf Nilsson, Anders Cavallin, Linnéa Bergenholm, Marcus Henricsson, V. Sashi Gopaul, Rahul Agrawal, Steven E. Nissen, Eva Hurt-Camejo
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
We investigated the effects of chronic oral administration of mineral oil, versus corn oil as control, on intestinal permeability, inflammatory markers, and plasma lipids in APOE*3-Leiden.CETP mice. Mice received mineral oil or corn oil 15 or 30 μL/
Externí odkaz:
https://doaj.org/article/355e56a08a754992859517641f71b9b7
Autor:
Lars Löfgren, Marcus Ståhlman, Gun-Britt Forsberg, Sinikka Saarinen, Ralf Nilsson, Göran I. Hansson
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 8, Pp 1690-1700 (2012)
Lipid extraction from biological samples is a critical and often tedious preanalytical step in lipid research. Primarily on the basis of automation criteria, we have developed the BUME method, a novel chloroform-free total lipid extraction method for
Externí odkaz:
https://doaj.org/article/19c328f14b9e462b91c746cab55b93f0
Autor:
Eva Persson, Lars Löfgren, Göran Hansson, Bertil Abrahamsson, Hans Lennernäs, Ralf Nilsson
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 1, Pp 242-251 (2007)
The purpose of the study reported here was to develop a method for the determination of lipid classes in intestinal fluids, including bile acids (BAs). A solid-phase extraction (SPE) method using C18 and silica columns for the separation of BAs, phos
Externí odkaz:
https://doaj.org/article/32274583c0e74aabad4f045fbe1fd2d1
Autor:
Mikael Bjursell, Xiufeng Xu, Therése Admyre, Gerhard Böttcher, Sofia Lundin, Ralf Nilsson, Virginia M Stone, Noel G Morgan, Yan Y Lam, Leonard H Storlien, Daniel Lindén, David M Smith, Mohammad Bohlooly-Y, Jan Oscarsson
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114942 (2014)
GPR120 (Ffar4) has been postulated to represent an important receptor mediating the improved metabolic profile seen upon ingestion of a diet enriched in polyunsaturated fatty acids (PUFAs). GPR120 is highly expressed in the digestive system, adipose
Externí odkaz:
https://doaj.org/article/484465c51f7048c088e91a0e6698af4a
Autor:
Henrik, Palmgren, Kasparas, Petkevicius, Stefano, Bartesaghi, Andrea, Ahnmark, Mario, Ruiz, Ralf, Nilsson, Lars, Löfgren, Matthew S, Glover, Anne-Christine, Andréasson, Liselotte, Andersson, Cécile, Becquart, Michael, Kurczy, Bengt, Kull, Simonetta, Wallin, Daniel, Karlsson, Sonja, Hess, Marcello, Maresca, Mohammad, Bohlooly-Y, Xiao-Rong, Peng, Marc, Pilon
Increased saturated fatty acid levels in membrane phospholipids have been implicated in the development of metabolic disease. Here, we tested the hypothesis that increased saturated fatty acid (SFA) content in cell membranes negatively impacts adipoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602e4660fb2096f0c15018ddd50c1efd
https://doi.org/10.2337/figshare.21782726.v2
https://doi.org/10.2337/figshare.21782726.v2
Autor:
Hanna Duàn, Marie Strimfors, Anna Salvati, Johan Ulander, Rita Salgado Ribeiro, Alan Sabirsh, Kai Liu, Daniel Lindén, Tasso Miliotis, Ralf Nilsson, Elisa Lázaro-Ibáñez, Michael Lerche
Lipid nanoparticles (LNPs) are currently of great interest for therapeutic nucleic acid delivery. Lipid-based nanoparticles are, however, difficult to study analytically and so our understanding of the interaction between LNPs and biological systems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15e26381450ce656ed9abddc3947dc33
https://doi.org/10.21203/rs.3.rs-827883/v1
https://doi.org/10.21203/rs.3.rs-827883/v1
Autor:
Marcus Henricsson, Ralf Nilsson, Anders Cavallin, V. Sashi Gopaul, Eva Hurt-Camejo, Hans M.G. Princen, Linnéa Bergenholm, Steven E. Nissen, Rahul Agrawal, Annica Jarke, Elsbet J. Pieterman
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Vol 12 (2021)
We investigated the effects of chronic oral administration of mineral oil, versus corn oil as control, on intestinal permeability, inflammatory markers, and plasma lipids in APOE*3-Leiden.CETP mice. Mice received mineral oil or corn oil 15 or 30 μL/
Publikováno v:
Journal of Internal Medicine. 274:263-272
OBJECTIVES: Heterozygous mutations in hepatocyte nuclear factor 1α (HNF1α) cause maturity onset diabetes of the young 3 (MODY3), an autosomal dominant form of diabetes. Deficiency of HNF1α in mice results in diabetes, hypercholesterolaemia and inc