Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Ralf Landgraf"'
Autor:
Ralf Landgraf, Qian Zhang
Publikováno v:
Pharmaceuticals, Vol 5, Iss 5, Pp 493-513 (2012)
The use of nucleic acid derived aptamers has rapidly expanded since the introduction of SELEX in 1990. Nucleic acid aptamers have demonstrated their ability to target a broad range of molecules in ways that rival antibodies, but advances have been ve
Externí odkaz:
https://doaj.org/article/00449edace0b46609908df8235494b9f
Publikováno v:
Metals, Vol 8, Iss 2, p 128 (2018)
This work shows a sequence of numerical models for the simulation of the Presta joining process: a well-established industrial process for manufacturing assembled camshafts. The operation is divided into two sub-steps: the rolling of the shaft to wid
Externí odkaz:
https://doaj.org/article/6e689751818f4c1e9923328336d8029c
Supplementary Figure 1: After four hours of treatment with 10 μM WA, very low levels of ERBB2 in MD-MBA-231 are further reduced and drop below detection; Supplementary Figure 2: At 10 μM, the addition of WA to BT474 cells elicits a ligand-like resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b723d1d2b73e1b8faa001396816da718
https://doi.org/10.1158/1535-7163.22507083
https://doi.org/10.1158/1535-7163.22507083
The catalytically deficient ERBB3 strongly synergizes with the receptor tyrosine kinase ERBB2, and elevated levels represent an overall risk factor for unfavorable disease outcomes in breast cancer. Although itself not a target of pan-ERBB kinase inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fed38e2c7e163c9080c50d86b3f9bf8a
https://doi.org/10.1158/1535-7163.c.6538575.v1
https://doi.org/10.1158/1535-7163.c.6538575.v1
Autor:
Anthony J. Capobianco, Alexander D. MacKerell, David J. Robbins, Ralf Landgraf, Ethan Lee, Leif R. Neitzel, Darren Orton, Pedro E.M. Lopes, Taiji Oashi, Kelly Weaver, Xiaoxia Zhu, Jeffrey VanWye, Ke Jin, Xiaoqing Han, Zhiqiang Wang, Thiago G. Da Silva, Luisana Astudillo
IMR-1 inhibits tumor growth in OE19 xenograft tumor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f7fa8bdf9b19ae71cb98925deeb026
https://doi.org/10.1158/0008-5472.22410887.v1
https://doi.org/10.1158/0008-5472.22410887.v1
Autor:
Anthony J. Capobianco, Alexander D. MacKerell, David J. Robbins, Ralf Landgraf, Ethan Lee, Leif R. Neitzel, Darren Orton, Pedro E.M. Lopes, Taiji Oashi, Kelly Weaver, Xiaoxia Zhu, Jeffrey VanWye, Ke Jin, Xiaoqing Han, Zhiqiang Wang, Thiago G. Da Silva, Luisana Astudillo
In many cancers, aberrant Notch activity has been demonstrated to play a role in the initiation and maintenance of the neoplastic phenotype and in cancer stem cells, which may allude to its additional involvement in metastasis and resistance to thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220daec9b258ba91a9183aa99bf40f97
https://doi.org/10.1158/0008-5472.c.6508100
https://doi.org/10.1158/0008-5472.c.6508100
Autor:
Anthony J. Capobianco, Alexander D. MacKerell, David J. Robbins, Ralf Landgraf, Ethan Lee, Leif R. Neitzel, Darren Orton, Pedro E.M. Lopes, Taiji Oashi, Kelly Weaver, Xiaoxia Zhu, Jeffrey VanWye, Ke Jin, Xiaoqing Han, Zhiqiang Wang, Thiago G. Da Silva, Luisana Astudillo
IMR-1 treatment does not induce weight loss in treated mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e1a8aad83b05b0c6daf68f4ad7c33f
https://doi.org/10.1158/0008-5472.22410884
https://doi.org/10.1158/0008-5472.22410884
Autor:
Sushanth Gouni, Paolo Strati, Gokce Toruner, Akanksha Aradhya, Ralf Landgraf, Daniel Bilbao, Francisco Vega, Nitin Kumar Agarwal
Publikováno v:
Leukemia & Lymphoma. 63:1302-1313
The beneficial effect of statins on the anti-lymphoma activity of the rituximab-based chemotherapy regimen is controversial. Here, we retrospectively reviewed patients with naïve-treated advanced diffuse large B-cell lymphoma (DLBCL) receiving front
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a06cdc57cffb0ad837a710421bfac2
https://doi.org/10.1080/10428194.2021.2020782
https://doi.org/10.1080/10428194.2021.2020782
Publikováno v:
Journal of Rubber Research. 24:211-225
In this paper, experimental and numerical investigations on cord–elastomer composites are presented. A finite-element model is introduced, which was developed within the framework of an industrial project. The model is able to simulate an elastomer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df26b19650e1df59c61a68a7e6835d4c
https://doi.org/10.1007/s42464-021-00091-x
https://doi.org/10.1007/s42464-021-00091-x
Autor:
Lysander Jankowsky, Ralf Landgraf, Stefan Hoyer, Welf-Guntram Drossel, Erik Oelsch, Martin Kausch, Jörn Ihlemann
Publikováno v:
Journal of Rubber Research. 24:249-256
3D printing opens up new possibilities for the production of polymeric structures that would not be possible with injection molding. However, it is known that the manufacturing method might have an impact on the mechanical properties of manufactured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7306e88ef34a230cf258165a0573a4f9
https://doi.org/10.1007/s42464-021-00092-w
https://doi.org/10.1007/s42464-021-00092-w