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Autor:
Jennifer C. Regan, Yu-Xuan Lu, Enric Ureña, Ralf L. Meilenbrock, James H. Catterson, Disna Kißler, Jenny Fröhlich, Emilie Funk, Linda Partridge
Publikováno v:
Regan, J C, Lu, Y X, Ureña, E, Meilenbrock, R L, Catterson, J H, Kißler, D, Fröhlich, J, Funk, E & Partridge, L 2022, ' Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin ', Nature Aging, vol. 2, no. 12, pp. 1145-1158 . https://doi.org/10.1038/s43587-022-00308-7
Nature Aging
Nature aging
Nature Aging
Nature aging
Pharmacological attenuation of mTOR presents a promising route for delay of age-related disease. Here we show that treatment of Drosophila with the mTOR inhibitor rapamycin extends lifespan in females, but not in males. Female-specific, age-related g