Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ralf Kueppers"'
Autor:
S. David Hudnall, Ralf Küppers
This text provides a comprehensive and up-to-date overview of Hodgkin lymphoma. The volume reviews every facet of the cancer in great detail, including pathology, pathobiology, molecular genetics, microenvironment, epidemiology, treatment, and new th
Autor:
Pieter van der Vlies, Anke van den Berg, Tjasso Blokzijl, Cigdem Atayar, Debora de Jong, Klaas Kok, Ralf Kueppers, Ines Pfeil, Geert Harms, Arjan Diepstra, Joost Kluiver, Sibrand Poppema
Publikováno v:
HEMATOLOGICAL ONCOLOGY, 25(1), 21-29. Wiley
To identify genes involved in the pathogenesis of classical Hodgkin lymphoma (cHL), we performed serial analysis of gene expression (SAGE) and array-based comparative genomic hybridization (aCGH). Comparison of SAGE libraries of cHL cell lines L428 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0e08b79310718bb1caca1ce556baf1
https://doi.org/10.1002/hon.804
https://doi.org/10.1002/hon.804
Autor:
Marc Seifert, Yassen Assenov, Lei Gu, Olga Bogatyrova, Dieter Weichenhan, Daniel B. Lipka, Sandra D Koser, David Brocks, Laura Z. Rassenti, Hartmut Döhner, Charles D. Imbusch, Ralf Kueppers, Qi Wang, Thomas J. Kipps, Peter Lichter, Thorsten Zenz, Christopher C. Oakes, Amy S. Ruppert, Stephan Stilgenbauer, Christoph Plass, Benedikt Brors, Martina Przekopowitz, Andrius Serva, John C. Byrd, Marc Zapatka, Daniel Mertens
Publikováno v:
Blood. 126:2436-2436
The malignant phenotype combines characteristics that are acquired and inherited from the normal cell of origin. Hematological malignancies and related disease subtypes are thought to arise from diverse cell types that may reflect various development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da83fbc758296516fa95a22765de2d28
https://doi.org/10.1182/blood.v126.23.2436.2436
https://doi.org/10.1182/blood.v126.23.2436.2436
Autor:
Daniel Mertens, Peter Lichter, Christopher C. Oakes, Marc Zapatka, Ralf Kueppers, Amy S. Ruppert, Olga Bogatyrova, Lei Gu, Sandra D Koser, Thorsten Zenz, Andrius Serva, David Brocks, Stephan Stilgenbauer, Martina Przekopowitz, Daniel B. Lipka, Assenov Yassen, Marc Seifert, Christoph Plass, Hartmut Doehner, John C. Byrd
Publikováno v:
Clinical Cancer Research. 21:B25-B25
Knowledge of the cell-of-origin is essential for the full understanding of the causes of a malignant disease and for the rational design of targeted therapies. The B cell compartment is composed of a highly complex mixture of subtypes, each with dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b24d9be7f331c53c54ddc95a4e669c43
https://doi.org/10.1158/1557-3265.hemmal14-b25
https://doi.org/10.1158/1557-3265.hemmal14-b25
Autor:
Heiko Trautmann, Dirk Hasenclever, Ralf Kueppers, Christiane Pott, Monika Szczepanowski, Ole Ammerpohl, Dietrich Herrmann, Wolfram Klapper, Andrea Haake, Steve Hoffmann, Markus Kreuz, Markus Loeffler, Karsten Winter, René Scholtysik, Maciej Rosolowski, Christian Arnold, Reiner Siebert
Publikováno v:
Blood. 122:502-502
Background Follicular lymphoma (FL) is a B-cell lymphoma whose cytogenetic hallmark is the translocation t(14;18)(q32;q21) which juxtaposes the BCL2 oncogene to the immunoglobulin heavy chain locus (IGHV). FLs maintain key features of normal germinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::761ff6e32de1c88bcd0face9dc47224f
https://doi.org/10.1182/blood.v122.21.502.502
https://doi.org/10.1182/blood.v122.21.502.502
Autor:
Ralf Kueppers, Ulrich Duehrsen, Tanja Boes, Holger Nueckel, Ludger Klein-Hitpass, Ludger Sellmann, Jan Duerig, René Scholtysik, Alexander Carpinteiro
Publikováno v:
Blood. 114:2640-2640
Abstract 2640 Poster Board II-616 Introduction: Deletion of 13q14 (del13q14) is the most common abnormality of B-chronic lymphocytic leukemia (CLL). However, for a long time investigations of this region did not detect the relevant pathogenetic mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23729f0e05813f65749e08a957b2381d
https://doi.org/10.1182/blood.v114.22.2640.2640
https://doi.org/10.1182/blood.v114.22.2640.2640
Autor:
Gabriela M. Baerlocher, Marc Seifert, Ralf Kueppers, Alexander Roeth, Ulrich Duehrsen, Astrid Mueller, Dirk de Beer
Publikováno v:
Blood. 112:1542-1542
BACKGROUND: In contrast to human granulocytes and T-cells with a quite homogenous decrease in telomere lengths over age, telomere lengths of peripheral blood B-cell populations are highly heterogeneous with average telomere lengths of B-cells remaini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dd56e0f5a2cbe4481b25691e272865d
https://doi.org/10.1182/blood.v112.11.1542.1542
https://doi.org/10.1182/blood.v112.11.1542.1542