Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Ralf Kiesling"'
1
Palladium Nanoparticles for the Deuteration and Tritiation of Benzylic Positions on Complex Molecules
Autor: Ralf Kiesling, Thomas Zeltner, Anja Kraemer, Albert Zeller, Julian Thoma, Christian Fackler, Viktor Pfeifer
Publikováno v: Angewandte Chemie International Edition. 60:26671-26676
Palladium nanoparticles (PdNp) were revealed as an efficient hydrogen isotope exchange catalyst for the deuterium and tritium labeling of benzylic positions of complex molecules. A practical way to obtain small palladium nanoparticles and to apply th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33fb189bbd11a3073574499bf702aaf
https://doi.org/10.1002/anie.202109043
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2
Easy-to-Implement Hydrogen Isotope Exchange for the Labeling of
Autor: Etienne, Levernier, Kevin, Tatoueix, Sébastien, Garcia-Argote, Viktor, Pfeifer, Ralf, Kiesling, Edmond, Gravel, Sophie, Feuillastre, Grégory, Pieters
Publikováno v: JACS Au. 2(4)
Facilitating access to deuterated and tritiated complex molecules is of paramount importance due to the fundamental role of isotopically labeled compounds in drug discovery and development. Deuterated analogues of drugs are extensively used as intern
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ec7c21b18a3775a2e797c8bd8468fb7f
https://pubmed.ncbi.nlm.nih.gov/35557763
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5
Carbon-13 and carbon-14 labeled dabigatran etexilate and tritium labeled dabigatran
Autor: Ralf Kiesling, Stefan Aßfalg, Chris H. Senanayake, Nina C. Gonnella, Max Chevliakov, Matt Hrapchak, Bachir Latli, Carl A. Busacca, Scot Campbell
Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 59:648-656
Dabigatran etexilate or pradaxa, a novel oral anticoagulant, is a reversible, competitive, direct thrombin inhibitor. It is used to prevent strokes in patients with atrial fibrillation and the formation of blood clots in the veins (deep venous thromb
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3bf4c3c455cec18b6f0ad31f71611f53
https://doi.org/10.1002/jlcr.3402
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6
Carbon-13 and carbon-14 labeled dabigatran etexilate and tritium labeled dabigatran
Autor: Bachir, Latli, Ralf, Kiesling, Stefan, Aßfalg, Max, Chevliakov, Matt, Hrapchak, Scot, Campbell, Nina, Gonnella, Carl A, Busacca, Chris H, Senanayake
Publikováno v: Journal of labelled compoundsradiopharmaceuticals. 59(14)
Dabigatran etexilate or pradaxa, a novel oral anticoagulant, is a reversible, competitive, direct thrombin inhibitor. It is used to prevent strokes in patients with atrial fibrillation and the formation of blood clots in the veins (deep venous thromb
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1f2f2c02e3860d2091d79f82b08c3d05
https://pubmed.ncbi.nlm.nih.gov/27146196
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7
Functional and Biochemical Rationales for the 24-Hour-Long Duration of Action of Olodaterol
Autor: Peter Sieger, Ines Kollak, Ralf Kiesling, Michael P. Pieper, Andreas Schnapp, Paola Casarosa, Tobias Kiechle, Angela Ostermann, Florian Gantner
Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 337:600-609
β 2 -Adrenoceptor (β 2 -AR) agonists are powerful bronchodilators and play a pivotal role in the management of pulmonary obstructive diseases, such as asthma and chronic obstructive pulmonary disease. Although these agents first were used many year
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01efe8438f3774856c49f2705873dd61
https://doi.org/10.1124/jpet.111.179259
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