Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Ralf Kemmerling"'
Autor:
Heinz-Josef Lenz, Alfredo Falcone, Chiara Cremolini, Fotios Loupakis, Shinichi Yamauchi, Satoshi Matsusaka, Yu Sunakawa, Stefan Stremitzer, Ana Sebio, Yan Ning, Dongyun Yang, Matthias Folwaczny, Andreas Jung, Thomas Kirchner, Ralf Kemmerling, Daniel Neureiter, Volker Heinemann, Wu Zhang, Sebastian Stintzing
Transmembrane receptors, such as the EGFR, are regulated by their turnover, which is dependent on the ubiquitin-proteasome system. We tested in two independent study cohorts whether SNPs in genes involved in EGFR turnover predict clinical outcome in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc3db66952022dc00cdfb288480c2558
https://doi.org/10.1158/1535-7163.c.6536866.v1
https://doi.org/10.1158/1535-7163.c.6536866.v1
Autor:
Heinz-Josef Lenz, Alfredo Falcone, Chiara Cremolini, Fotios Loupakis, Shinichi Yamauchi, Satoshi Matsusaka, Yu Sunakawa, Stefan Stremitzer, Ana Sebio, Yan Ning, Dongyun Yang, Matthias Folwaczny, Andreas Jung, Thomas Kirchner, Ralf Kemmerling, Daniel Neureiter, Volker Heinemann, Wu Zhang, Sebastian Stintzing
Supplemental Tables giving detailed information about rs985374 genotypes and efficacy in FIRE-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a05e5a0e6ac1f42d90710532fac706
https://doi.org/10.1158/1535-7163.22501684.v1
https://doi.org/10.1158/1535-7163.22501684.v1
Autor:
Timo Gaiser, Thomas Ried, Paul S. Meltzer, Jordi Camps, Sean Davis, Ralf Kemmerling, Daniela Hirsch
Supplementary Table S1 PDF file 43K,Summary of aCGH gains and losses in the 18 MM samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a772357db14631c431b20b9447b442f
https://doi.org/10.1158/0008-5472.22398536
https://doi.org/10.1158/0008-5472.22398536
Autor:
René Günther Feichtinger, Daniel Neureiter, Ralf Kemmerling, Johannes Adalbert Mayr, Tobias Kiesslich, Barbara Kofler
Publikováno v:
Cells, Vol 8, Iss 6, p 539 (2019)
Cancer cells frequently exhibit dysfunctional oxidative phosphorylation (OXPHOS) and a concomitant increase in glycolytic flux. We investigated the expression of OXPHOS complex subunits and mitochondrial mass in 34 human cholangiocellular carcinomas
Externí odkaz:
https://doaj.org/article/ec54debdd54b4f40a7994d2dac2d895f
Autor:
Timo Gaiser, Lissa Berroa-Garcia, Ralf Kemmerling, Aparajita Dutta, Thomas Ried, Kerstin Heselmeyer-Haddad
Publikováno v:
Analytical Cellular Pathology, Vol 33, Iss 2, Pp 105-112 (2010)
Background: The simultaneous detection of protein expression and gene copy number changes in patient samples, like paraffin-embedded tissue sections, is challenging since the procedures of immunohistochemistry (IHC) and Fluorescence in situ Hybridiza
Externí odkaz:
https://doaj.org/article/4893dca127924e17901960d911d2bab2
Publikováno v:
Analytical Cellular Pathology, Vol 23, Iss 1, Pp 29-37 (2001)
Comparative genomic hybridization (CGH) is a modern genetic method which enables a genome‐wide survey of chromosomal imbalances. For each chromosome region, one obtains the information whether there is a loss or gain of genetic material, or whether
Externí odkaz:
https://doaj.org/article/313250f860ba4a35a093e9b0bcf554df
Autor:
Daniel Neureiter, René G. Feichtinger, Ralf Kemmerling, Barbara Kofler, Tobias Kiesslich, Johannes A. Mayr
Publikováno v:
Cells
Cells, Vol 8, Iss 6, p 539 (2019)
Volume 8
Issue 6
Cells, Vol 8, Iss 6, p 539 (2019)
Volume 8
Issue 6
Cancer cells frequently exhibit dysfunctional oxidative phosphorylation (OXPHOS) and a concomitant increase in glycolytic flux. We investigated the expression of OXPHOS complex subunits and mitochondrial mass in 34 human cholangiocellular carcinomas
Autor:
Daniel Neureiter, Romana Illig, Tarkan Jäger, Maximilian Pichelstorfer, Tobias Kiesslich, A. Dinnewitzer, Stefan Swierczynski, Denis Weyland, Ralf Kemmerling, Eckhard Klieser
Publikováno v:
Molecular and Clinical Oncology. 4:763-773
The aim of this study was to provide a standardized risk stratification model for gastrointestinal stromal tumors (GISTs) based on tumor localization, tumor size, involved lymph nodes and metastases, as well as mitotic activity and other morphologica
Autor:
Richard Greil, Lisa Pleyer, Georg Hopfinger, Susanne Steinkirchner, Ann Boekstegers, Daniel Neureiter, Jutta Auberger, Alexander Egle, Ralf Kemmerling, Patrick Morre, Clemens Hufnagl, Lukas Weiss, Thomas Melchardt
Publikováno v:
Leukemia & Lymphoma. 56:353-360
Clinical and/or biological risk factors are needed to identify elderly patients with aggressive B-cell lymphoma able to receive full-dose R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone) treatment. We present a retrospective
Autor:
Daniel Neureiter, Romana Illig, Denis Weyland, Ralf Kemmerling, Tobias Kiesslich, Eckhard Klieser, Tarkan Jäger, Otto Dietze
Publikováno v:
Oncology Letters
Risk stratification of gastrointestinal stromal tumors (GISTs) by tumor size, lymph node and metastasis status is crucially affected by mitotic activity. To date, no studies have quantitatively compared mitotic activity in hematoxylin and eosin (H&E)