Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Ralf Jesnowski"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 9, Pp 740-747 (2010)
Gemcitabine is widely used as first-line chemotherapeutic drug in the treatment of pancreatic cancer. Our previous experimental chemotherapy studies have shown that treatment of human pancreatic carcinoma cells with 5-fluorouracil (5-FU) alters the c
Externí odkaz:
https://doaj.org/article/3ea2ac64ff4b4e5abbf113a5b013db49
Publikováno v:
Cancers
Cancers, Vol 3, Iss 1, Pp 106-125 (2010)
Cancers, Vol 3, Iss 1, Pp 106-125 (2010)
Pancreatic cancer ranks among the tumors most resistant to chemotherapy. Such chemoresistance of tumors can be mediated by various cellular mechanisms including dysregulated apoptosis or ineffective drug concentration at the intracellular target site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ef2fdd1b358d175177181ca5f70c33
http://europepmc.org/articles/PMC3756352
http://europepmc.org/articles/PMC3756352
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 9, Pp 740-747 (2010)
Gemcitabine is widely used as first-line chemotherapeutic drug in the treatment of pancreatic cancer. Our previous experimental chemotherapy studies have shown that treatment of human pancreatic carcinoma cells with 5-fluorouracil (5-FU) alters the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f884ad8209e4484d38a7d54c8e109074
http://www.sciencedirect.com/science/article/pii/S1476558610800752
http://www.sciencedirect.com/science/article/pii/S1476558610800752
Publikováno v:
Advanced Engineering Materials. 11:B129-B135
Cell encapsulation represents an innovative technique. However, clinical applications are sparse. Most experiments and clinical studies have been performed with either alginate or cellulose sulfate capsules, containing several cell lines and a broad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09088f2ab06c901aadb1b5471cb31f37
https://doi.org/10.1002/adem.200800409
https://doi.org/10.1002/adem.200800409
Publikováno v:
Pancreatology. 9:136-144
Background: Pancreatic cancer is characterized by high resistance to chemotherapy. Such chemoresistance can be mediated by multidrug resistance proteins (MRPs), breast cancer resistance protein (BCRP), and MDR1 P-glycoprotein. However, the contributi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1cc04060836b5e8a7344ecf0158d9d8
https://doi.org/10.1159/000178884
https://doi.org/10.1159/000178884
Autor:
Martin R. Berger, Jörg Kleeff, Helmut Friess, Xiaohua Jiang, Hany Kayed, Shereen Keleg, Thomas Giese, Matthias Löhr, Ralf Jesnowski, Irene Esposito
Publikováno v:
British Journal of Cancer
Recent evidence suggests that Runt-related transcription factors play a role in different human tumours. In the present study, the localisation of the Runt-related transcription factor-2 (Runx2), its transcriptional activity, as well as its regulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7e2be40250b80a5ffd14dcf75a8a17
http://europepmc.org/articles/PMC2360444
http://europepmc.org/articles/PMC2360444
Publikováno v:
Zeitschrift für Gastroenterologie. 41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f688e5bc5773998700c3feddee8de185
https://doi.org/10.1055/s-0035-1555190
https://doi.org/10.1055/s-0035-1555190
Autor:
Jens Ringel, Surinder K. Batra, Ralf Jesnowski, Amit Choudhury, Nicolas Moniaux, Jörg Ringel, Günter Klöppel, Matthias Löhr, Jutta Lüttges
Publikováno v:
Cancer Research. 66:9045-9053
A disintegrin and metalloproteinase (ADAM) molecules are known for their unique potential to combine adhesion, proteolysis, and signaling. To understand the role of ADAM17/tumor necrosis factor-α (TNF-α) converting enzyme (TACE) in pancreatic ducta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629f4ee1640afe5ce1c15689f1977104
https://doi.org/10.1158/0008-5472.can-05-3287
https://doi.org/10.1158/0008-5472.can-05-3287
Autor:
Jörg Kleeff, Matthias Löhr, Armin Kolb, Jörg Ringel, Daniel Fürst, Ralf Jesnowski, Ying Chen, Wolfgang Schareck, Andrea Schrödel
Publikováno v:
Laboratory Investigation. 85:1276-1291
Tissue fibrosis is one of the characteristics of chronic pancreatitis and pancreatic adenocarcinoma. Activated pancreatic stellate cells (PSC) play a central role in this process. However, analysis of the molecular mechanisms leading to PSC activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e009df790cb7ce311e8ec3073b101d
https://doi.org/10.1038/labinvest.3700329
https://doi.org/10.1038/labinvest.3700329
Autor:
Michael Schrewe, Matthias Löhr, Oliver V. Fabian, Robert Michael Saller, Eduard Ryschich, Walter Harms, Ralf Jesnowski, Jan Schmidt, Jörg Ringel, Alexander Engel
Publikováno v:
International Journal of Cancer. 113:649-653
Local therapy of pancreatic cancer with microencapsulated CYP2B1-producing cells and ifosfamide showed an effect both on the primary tumor and on distant metastatases. This possibly represents a consequence of the activation of immune response. Other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0147ed68a4c080a1b9ca67b8b31cc76a
https://doi.org/10.1002/ijc.20627
https://doi.org/10.1002/ijc.20627