Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ralf Jürgen Kuban"'
Autor:
Karsten Jürchott, Ralf-Jürgen Kuban, Till Krech, Nils Blüthgen, Ulrike Stein, Wolfgang Walther, Christian Friese, Szymon M Kiełbasa, Ute Ungethüm, Per Lund, Thomas Knösel, Wolfgang Kemmner, Markus Morkel, Johannes Fritzmann, Peter M Schlag, Walter Birchmeier, Tammo Krueger, Silke Sperling, Christine Sers, Hans-Dieter Royer, Hanspeter Herzel, Reinhold Schäfer
Publikováno v:
PLoS Genetics, Vol 6, Iss 12, p e1001231 (2010)
Transcriptional signatures are an indispensible source of correlative information on disease-related molecular alterations on a genome-wide level. Numerous candidate genes involved in disease and in factors of predictive, as well as of prognostic, va
Externí odkaz:
https://doaj.org/article/374dde0b6ad640c3b6dc0984ca6ebe07
Autor:
Barbara Ingold, Eva Simon, Ute Ungethüm, Ralf-Jürgen Kuban, Berit M Müller, Amelie Lupp, Ulf Neumann, Matthias P A Ebert, Carsten Denkert, Wilko Weichert, Stefan Schulz, Christoph Röcken
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10087 (2010)
BACKGROUND: G-protein-coupled receptors (GPCRs) are prime candidates for novel cancer prevention and treatment strategies. We searched for differentially expressed GPCRs in node positive gastric carcinomas. METHODOLOGY/PRINCIPAL FINDINGS: Differentia
Externí odkaz:
https://doaj.org/article/c27f9da7364b45d08f86220941190059
Autor:
Helmy Rachman, Nayoung Kim, Timo Ulrichs, Sven Baumann, Lydia Pradl, Ali Nasser Eddine, Matthias Bild, Marion Rother, Ralf-Jürgen Kuban, Jong Seok Lee, Robert Hurwitz, Volker Brinkmann, George A Kosmiadi, Stefan H E Kaufmann
Publikováno v:
PLoS ONE, Vol 1, p e29 (2006)
Apoptosis and activation of macrophages play an important role in the host response to mycobacterial infection involving TNF-alpha as a critical autocrine mediator. The underlying mechanisms are still ill-defined. Here, we demonstrate elevated levels
Externí odkaz:
https://doaj.org/article/5f8a0d7b31f94a7389283a431a7462cf
Autor:
Dikla Ben-Shushan, Dror Harats, Yehuda Kamari, Hartmut Kühn, Aviv Shaish, Iris Barshack, Maya Sultan, Shulamit Isman, Michael Peled, Ralf-Jürgen Kuban
Publikováno v:
Advances in medical sciences. 65(1)
Purpose Lipoxygenases (LOX) have been implicated in carcinogenesis, however both pro- and anti-carcinogenic effects have been reported in different cancer models. Using transgenic mice, which specifically overexpress human 15-lipoxygenase (ALOX15) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3a005042c908debf6b4dc18d1d53c6
https://pubmed.ncbi.nlm.nih.gov/31923770
https://pubmed.ncbi.nlm.nih.gov/31923770
Autor:
Katharina Spatz, Christiane Liezmann, Remo Campiche, Ralf Jürgen Kuban, Burghard F. Klapp, Maria Daniltchenko, Johannes Kruse, Ute Ungethüm, Dominik Imfeld, Eva M.J. Peters
Publikováno v:
Journal of Investigative Dermatology. 133:1150-1160
Determining hitherto uninvestigated and safe targets to halt the aging process is important in our aging society. Graying is a hallmark of the aging process and may be used to identify aging tissue for comparative analysis. Here we analyzed different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06aa56d11825fc5588cac519ac89f61a
https://doi.org/10.1038/jid.2012.462
https://doi.org/10.1038/jid.2012.462
De novo expression of EphA2 in osteosarcoma modulates activation of the mitogenic signalling pathway
Autor:
Per-Ulf Tunn, Christine Sers, Veit Krenn, Aurelia Noske, Ute Ungethüm, Manfred Dietel, Peter M. Schlag, Janine Karle, Raphaela Fritsche-Guenther, Ralf-Jürgen Kuban
Publikováno v:
Histopathology. 57:836-850
Aims: In osteosarcoma patients the development of metastases, often to the lungs, is the most frequent cause of death. The aim of this study was to elucidate the molecular mechanisms governing osteosarcoma development and dissemination and, thereby,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f491b6e8b946e79f124985336c91e2b6
https://doi.org/10.1111/j.1365-2559.2010.03713.x
https://doi.org/10.1111/j.1365-2559.2010.03713.x
Autor:
Christoph Röcken, Ulf Neumann, Ralf Jürgen Kuban, Ute Ungethüm, Atsuko Kasajima, Oleg I. Tchernitsa, Matthias P.A. Ebert, Balazs Gyorffy, Eva Simon, Wilko Weichert, Reinhold Schäfer
Publikováno v:
The Journal of Pathology. 222:310-319
We investigated the differential expression of Dicer and Drosha, as well as that of microRNA (miRNA), in adjacent normal and tumour samples of patients with gastric cancer. The expression of Dicer and Drosha was studied by immunohistochemistry in 332
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc6e03c35d202b2ebe1d0c439d2c9ae2
https://doi.org/10.1002/path.2759
https://doi.org/10.1002/path.2759
Autor:
Ralf-Jürgen Kuban, Lars Morawietz, Veit Krenn, Christian Kaps, Hortense Slevogt, Andreas Weimann, Thorsten Gehrke, U. Ungethuem, M. G. Krukemeyer, Joerg H. Schroeder
Publikováno v:
Journal of Orthopaedic Research. 26:394-403
The aim of the study was to identify markers for the early diagnosis of endoprosthesis loosening, for the differentiation between wear particle-induced and septic loosening and to gather new insights into the pathogenesis of endoprosthesis loosening.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a07b6205df7741c7fa6254e1dbb225
https://doi.org/10.1002/jor.20485
https://doi.org/10.1002/jor.20485
Autor:
Birgit Mazurek, Nyamaa Amarjargal, Wolfgang Henke, Astrid Machulik, Ralf-Jürgen Kuban, Agnieszka J. Szczepek, Heidemarie Haupt, Julia Fuchs, N. A. Andreeva, Elena E. Pohl, Johann Gross, Renate Moller, Ute Ungethüm, Frank-Uwe Fuchs
Publikováno v:
Brain Research. 1162:56-68
Cell death in the inner ear tissues is an important mechanism leading to hearing impairment. Here, using microarrays and real-time RT-PCR we analyzed expression of selected apoptosis-related genes in rat's inner ear. We determined the gene expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa1836e8b3a2725b4ce65a58829b7f0
https://doi.org/10.1016/j.brainres.2007.05.061
https://doi.org/10.1016/j.brainres.2007.05.061
Autor:
U. Ungethuem, Sonya C. Faber, V. Krenn, Hubert Wirtz, Ulrich Sack, Lars Morawietz, Stefan Hammerschmidt, Frank Emmrich, Franziska Lange, S. Härtl, Ralf-Jürgen Kuban
Publikováno v:
Scandinavian Journal of Immunology. 64:544-553
Joint destruction in rheumatoid arthritis (RA) starts typically at sites of mechanically stressed inserts of the synovial membrane near the cartilage/bone border. In the therapy of RA, tumour necrosis factor (TNF) antagonists have rapidly emerged as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2593721429b03abed54238c3ec500366
https://doi.org/10.1111/j.1365-3083.2006.01840.x
https://doi.org/10.1111/j.1365-3083.2006.01840.x