Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Ralf J, Rieker"'
Autor:
Leticija Zlatar, Jasmin Knopf, Jeeshan Singh, Han Wang, Marco Muñoz-Becerra, Irmgard Herrmann, Rebecca C. Chukwuanukwu, Markus Eckstein, Philip Eichhorn, Ralf J. Rieker, Elisabeth Naschberger, Andreas Burkovski, Veit Krenn, Rostyslav Bilyy, Tetiana Butova, Iryna Liskina, Ihor Kalabukha, Oleg Khmel, Michael Boettcher, Georg Schett, Dmytro Butov, Anton Tkachenko, Martin Herrmann
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-12 (2024)
Abstract Tuberculosis (TB) remains one of the top 10 causes of death worldwide and still poses a serious challenge to public health. Recent attention to neutrophils has uncovered unexplored areas demanding further investigation. Therefore, the aim of
Externí odkaz:
https://doaj.org/article/eea18bd40a674ab488cd864665af2707
Fiber rich food suppressed airway inflammation, GATA3 + Th2 cells, and FcεRIα+ eosinophils in asthma
Autor:
Alicia Schenzel, Adriana Geiger, Elvedina Nendel, Zuqin Yang, Susanne Krammer, Anna Leberle, Ann-Kathrin Brunst, Sonja Trump, Susanne Mittler, Manfred Rauh, Carol I. Geppert, Patrick Tausche, Katja Hohenberger, Ralf J. Rieker, Oliver Schieweck, Sebastian Zundler, Susetta Finotto
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundAllergic Asthma is a disease presenting various endotypes and no current therapies act curative but alleviate disease symptoms. Dietary interventions are gaining increasing importance in regulating immune responses. Furthermore, short chain
Externí odkaz:
https://doaj.org/article/39b0a87bb91247229f8164f0537f2605
Autor:
Philipp Hartmann, Denis I. Trufa, Katja Hohenberger, Patrick Tausche, Sonja Trump, Susanne Mittler, Carol I. Geppert, Ralf J. Rieker, Oliver Schieweck, Horia Sirbu, Arndt Hartmann, Susetta Finotto
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Neoplasms of the lungs are the leading cause of cancer incidence and mortality worldwide. Although immunotherapy has increased the overall survival of patients with lung cancer, there is the need to improve this treatment. At this regard, bl
Externí odkaz:
https://doaj.org/article/8208be4c350044d98812e834b5d8bad4
Autor:
Janina C. Grund, Susanne Krammer, RPh, Zuqin Yang, MSc, Hannah Mitländer, Manfred Rauh, PhD, Sabine Zirlik, MD, Alexander Kiefer, MD, Theodor Zimmermann, MD, Ralf J. Rieker, MD, Carol I. Geppert, MD, Nikolaos G. Papadopoulos, MD, Susetta Finotto, PhD
Publikováno v:
Journal of Allergy and Clinical Immunology: Global, Vol 2, Iss 3, Pp 100099- (2023)
Background: Vitamin D3 (VitD3) is known to have immunomodulatory functions, and VitD3 deficiency is associated with more severe asthma. Objective: We aimed to assess the immunoregulatory effects of VitD3 food supplementation on asthma manifestation,
Externí odkaz:
https://doaj.org/article/c7ef54dabe87475d9e5fdaca89eb3997
Autor:
Julia Kölle, Theodor Zimmermann, Alexander Kiefer, Ralf J. Rieker, Paraskevi Xepapadaki, Sebastian Zundler, Nikolaos G. Papadopoulos, Susetta Finotto
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104440- (2022)
Summary: The cytokine interleukin-3 (IL-3) acts on early hematopoietic precursor cells. In humans, Treg cells secrete IL-3 and repress inflammatory cells except for basophils. The present study aims to elucidate the contribution of IL-3 in the develo
Externí odkaz:
https://doaj.org/article/b332aab80fca4b019218138090718865
Autor:
Lisanne Heim, Zuqin Yang, Patrick Tausche, Katja Hohenberger, Mircea T. Chiriac, Julia Koelle, Carol-Immanuel Geppert, Katerina Kachler, Sarah Miksch, Anna Graser, Juliane Friedrich, Rakshin Kharwadkar, Ralf J. Rieker, Denis I. Trufa, Horia Sirbu, Markus F. Neurath, Mark H. Kaplan, Susetta Finotto
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Although lung cancer is the leading cause of cancer deaths worldwide, the mechanisms how lung cancer cells evade the immune system remain incompletely understood. Here, we discovered IL-9-dependent signaling mechanisms that drive immune evasion in no
Externí odkaz:
https://doaj.org/article/123c1359ce714a9b810a0f1bd63a872f
Autor:
Alexander Gähler, Denis I. Trufa, Mircea T. Chiriac, Patrick Tausche, Katja Hohenberger, Ann-Kathrin Brunst, Manfred Rauh, Carol I. Geppert, Ralf J. Rieker, Susanne Krammer, Anna Leberle, Markus F. Neurath, Horia Sirbu, Arndt Hartmann, Susetta Finotto
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundLung cancer is the second common cancer type in western countries and has a high mortality. During the development and progression of the tumor, the nutrients in its environment play a central role. The tumor cells depend crucially on gluco
Externí odkaz:
https://doaj.org/article/5af820fb33ba445790484f248af9f25f
Autor:
Jeeshan Singh, Irmgard Herrmann, Aparna Mahajan, Christine Schauer, Xiaomei Shan, Arndt Hartmann, Ralf J. Rieker, Katja Evert, Christina Falkeis, Elisabeth Naschberger, Saskia von Stillfried, Peter Boor, Luis E. Muñoz, Georg Schett, Martin Herrmann, Jasmin Knopf
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15126 (2022)
Vascular occlusions in patients with coronavirus diseases 2019 (COVID-19) have been frequently reported in severe outcomes mainly due to a dysregulation of neutrophils mediating neutrophil extracellular trap (NET) formation. Lung specimens from patie
Externí odkaz:
https://doaj.org/article/325cacbe9a8a48ab81b21c975c375728
Autor:
Moritz Leppkes, Jasmin Knopf, Elisabeth Naschberger, Aylin Lindemann, Jeeshan Singh, Irmgard Herrmann, Michael Stürzl, Léonie Staats, Aparna Mahajan, Christine Schauer, Anita N. Kremer, Simon Völkl, Kerstin Amann, Katja Evert, Christina Falkeis, Andreas Wehrfritz, Ralf J. Rieker, Arndt Hartmann, Andreas E. Kremer, Markus F. Neurath, Luis E. Muñoz, Georg Schett, Martin Herrmann
Publikováno v:
EBioMedicine, Vol 58, Iss , Pp 102925- (2020)
Background: Coronavirus induced disease 2019 (COVID-19) can be complicated by severe organ damage leading to dysfunction of the lungs and other organs. The processes that trigger organ damage in COVID-19 are incompletely understood. Methods: Samples
Externí odkaz:
https://doaj.org/article/724dc37caf5547c390e6022a21be3717
Autor:
Susetta Finotto, Johannes Kornhuber, Burkhard Kleuser, Horia Sirbu, Arndt Hartmann, Ralf J. Rieker, Denis I. Trufa, Juliana Monti, Susanne Mittler, Sonja Trump, Corinna D. Holzinger, Martin Reichel, Fabian Schumacher, Lisanne Heim, Maximilian Bailer, Katerina Kachler
Regulation of T cell phenotype and serum Ceramide/Sphingomyelin levels in wild type and ASM KO naïve and lung tumour bearing mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41578cf95ab68b62b1f23ab847f2137a
https://doi.org/10.1158/0008-5472.22418721
https://doi.org/10.1158/0008-5472.22418721
