Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Ralf Hass"'
Autor:
Thomas Dittmar, Ralf Hass
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Cellular fusion e.g. between cancer cells and normal cells represents a stepwise process that is tightly regulated. During a pre-hybrid preparation program somatic cells and/or cancer cells are promoted to a pro-fusogenic state as a prerequi
Externí odkaz:
https://doaj.org/article/1f564cbd0b454f23ac39ddde2e4044b8
Autor:
Ivana Ferrero, Filippo Piccinini, Pasquale Marrazzo, Manuela Monti, Caterina Pipino, Alessia Santa Giovanna Banche Niclot, Camilla Francesca Proto, Enrico Ragni, Ralf Hass, Giulia Maria Stella, Priscilla Berni, Ana Ivanovska, Katia Mareschi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2221 (2024)
The Second International StemNet (Federation of Stem Cell Research Associations) meeting took place on 18–20 October 2023 in Brescia (Italy), with the support of the University of Brescia and the Zooprophylactic Institute of Lombardy and Emilia Rom
Externí odkaz:
https://doaj.org/article/d1510fe8a5f74aa3b77c1ac744010148
Autor:
Britta Stapel, Catharina Melzer, Juliane von der Ohe, Peter Hillemanns, Stefan Bleich, Kai G. Kahl, Ralf Hass
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Breast cancer is the most prevalent malignancy amongst women worldwide while ovarian cancer represents the leading cause of death among gynecological malignancies. Women suffering from these cancers displayed heightened rates of major depres
Externí odkaz:
https://doaj.org/article/e507f04fc6874f6790b5573788c1ce10
Autor:
Thomas Dittmar, Ralf Hass
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16071 (2022)
Fusion among different cell populations represents a rare process that is mediated by both intrinsic and extracellular events. Cellular hybrid formation is relayed by orchestrating tightly regulated signaling pathways that can involve both normal and
Externí odkaz:
https://doaj.org/article/9a041a7c43364f819a8ee5338515cb92
Autor:
Yibo Xue, Brian Meehan, Elizabeth Macdonald, Sriram Venneti, Xue Qing D. Wang, Leora Witkowski, Petar Jelinic, Tim Kong, Daniel Martinez, Geneviève Morin, Michelle Firlit, Atefeh Abedini, Radia M. Johnson, Regina Cencic, Jay Patibandla, Hongbo Chen, Andreas I. Papadakis, Aurelie Auguste, Iris de Rink, Ron M. Kerkhoven, Nicholas Bertos, Walter H. Gotlieb, Blaise A. Clarke, Alexandra Leary, Michael Witcher, Marie-Christine Guiot, Jerry Pelletier, Josée Dostie, Morag Park, Alexander R. Judkins, Ralf Hass, Douglas A. Levine, Janusz Rak, Barbara Vanderhyden, William D. Foulkes, Sidong Huang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is driven by SMARCA4 loss. Here the authors demonstrate that SCCOHT cells are highly sensitive to CDK4/6 inhibition and provide mechanistic insights, whereby this druggable vulnerability
Externí odkaz:
https://doaj.org/article/a9bfc57c02f44dfc91dacd68ff8a6a66
Publikováno v:
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-9 (2018)
Abstract The tumor microenvironment enables important cellular interactions between cancer cells and recruited adjacent populations including mesenchymal stroma/stem cells (MSC). In vivo cellular interactions of primary human MSC in co-culture with h
Externí odkaz:
https://doaj.org/article/0e2b539b5c24467293b528ce5dca27c0
Publikováno v:
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-15 (2018)
Abstract Background Fusion of breast cancer cells with tumor-associated populations of the microenvironment including mesenchymal stroma/stem-like cells (MSC) represents a rare event in cell communication whereby the metastatic capacity of those hybr
Externí odkaz:
https://doaj.org/article/72065f6275de437a999f933504705fed
Autor:
Chieh Ming Liao, Tianjiao Luo, Juliane von der Ohe, Blanca de Juan Mora, Roland Schmitt, Ralf Hass
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13562 (2021)
Cellular senescence of renal tubular cells is associated with chronic diseases and age-related kidney disorders. Therapies to antagonize senescence are, therefore, explored as novel approaches in nephropathy. Exosomes derived from human mesenchymal s
Externí odkaz:
https://doaj.org/article/70e6a4c2bcf249ba9e32f0b04c8b95d3
Publikováno v:
Cancers, Vol 13, Iss 20, p 5212 (2021)
Exosomes derived from mesenchymal stroma-/stem-like cells (MSCs) as part of extracellular vesicles are considered cell-free biocompatible nanovesicles that promote repair activities of damaged tissues or organs by exhibiting low immunogenic and cytot
Externí odkaz:
https://doaj.org/article/81d7398cb90d43ec8567bda732d5ede8
Publikováno v:
Cancers, Vol 13, Iss 21, p 5363 (2021)
Cell fusion is a well-known, but still scarcely understood biological phenomenon, which might play a role in cancer initiation, progression and formation of metastases. Although the merging of two (cancer) cells appears simple, the entire process is
Externí odkaz:
https://doaj.org/article/81619e71834649f38ebcf6fb7bc71480