Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Ralf Fliegert"'
Autor:
Jelena Pick, Simon Sander, Stefanie Etzold, Anette Rosche, Henning Tidow, Andreas H. Guse, Ralf Fliegert
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
TRPM2 is a Ca2+ permeable, non-selective cation channel in the plasma membrane that is involved in the innate immune response regulating, for example, chemotaxis in neutrophils and cytokine secretion in monocytes and macrophages. The intracellular ad
Externí odkaz:
https://doaj.org/article/c5740e9dda0c4bb5b4009932a290188e
Autor:
Enja Schneider, Riekje Winzer, Anne Rissiek, Isabell Ricklefs, Catherine Meyer-Schwesinger, Franz L. Ricklefs, Andreas Bauche, Jochen Behrends, Rudolph Reimer, Santra Brenna, Hauke Wasielewski, Melchior Lauten, Björn Rissiek, Berta Puig, Filippo Cortesi, Tim Magnus, Ralf Fliegert, Christa E. Müller, Nicola Gagliani, Eva Tolosa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Ectonucleotidases associated to regulatory T cells are known modulators in the inflammatory environment. Here the authors describe CD8 T cell-derived extracellular vesicles bearing CD73 and suggest they function as an additional intrinsic modulator o
Externí odkaz:
https://doaj.org/article/423c6b103e9d4f51bf3e93a6880c1a59
Autor:
Natalie Baum, Marie Eggers, Julia Koenigsdorf, Stephan Menzel, Julia Hambach, Tobias Staehler, Ralf Fliegert, Frederike Kulow, Gerhard Adam, Friedrich Haag, Peter Bannas, Friedrich Koch-Nolte
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
CD38 is the major NAD+-hydrolyzing ecto-enzyme in most mammals. As a type II transmembrane protein, CD38 is also a promising target for the immunotherapy of multiple myeloma (MM). Nanobodies are single immunoglobulin variable domains from heavy chain
Externí odkaz:
https://doaj.org/article/f58fefb06a7e48fe8d38ef055edd83b6
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
TRPM2 is a non-selective, Ca2+-permeable cation channel widely expressed in immune cells. It is firmly established that the channel can be activated by intracellular adenosine 5′-diphosphoribose (ADPR). Until recent cryo-EM structures have exhibite
Externí odkaz:
https://doaj.org/article/8c988b0843ff4387a856009f9f035851
Autor:
Nicole Schwarz, Laurent Drouot, Annette Nicke, Ralf Fliegert, Olivier Boyer, Andreas H Guse, Friedrich Haag, Sahil Adriouch, Friedrich Koch-Nolte
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41269 (2012)
P2X7 is a homotrimeric ion channel with two transmembrane domains and a large extracellular ATP-binding domain. It plays a key role in the response of immune cells to danger signals released from cells at sites of inflammation. Gating of murine P2X7
Externí odkaz:
https://doaj.org/article/413bc3d8516842fdba242fbf07033ff3
Autor:
Louisa, Stern, Lukas Fabian, Boehme, Mara Rebecca, Goetz, Christine, Nitschke, Anastasios, Giannou, Tao, Zhang, Cenap, Güngör, Matthias, Reeh, Jakob Robert, Izbicki, Ralf, Fliegert, Anne, Hausen, Nathalia, Giese, Thilo, Hackert, Masha Y, Niv, Stefan, Heinrich, Matthias Martin, Gaida, Tarik, Ghadban
Publikováno v:
International Journal of Oncology. 62
Bitter taste receptors (T2Rs) are G protein‑coupled receptors originally detected in the gustatory system. More recently, T2Rs have been shown to be expressed in extra‑oral cells eliciting non‑gustatory functions. Emerging evidence has suggeste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3581195b0925f3948d8d41ae236098
https://doi.org/10.3892/ijo.2022.5454
https://doi.org/10.3892/ijo.2022.5454
Autor:
Simon Sander, Ralf Fliegert, Trevor J. Rutherford, Henning Tidow, Ellen Gattkowski, Andreas Bauche, Franziska Möckl
Publikováno v:
The FEBS journal 288(23), 6769-6782 (2021). doi:10.1111/febs.16097
The FEBS journal 288(23), 6769 - 6782 (2021). doi:10.1111/febs.16097
Nudix hydrolase 9 (NUDT9) is a member of the nucleoside linked to another moiety X (NUDIX) protein superfamily, which hydrolyses a broad spectrum of organic pyrophosphates from
Nudix hydrolase 9 (NUDT9) is a member of the nucleoside linked to another moiety X (NUDIX) protein superfamily, which hydrolyses a broad spectrum of organic pyrophosphates from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193e9de228d91112d6d0b07cc82257e7
https://doi.org/10.1111/febs.16097
https://doi.org/10.1111/febs.16097
Publikováno v:
Protein Science. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd06e3e0d36602e0845089ff8cee38db
https://doi.org/10.1002/pro.4320
https://doi.org/10.1002/pro.4320
Autor:
Parimah, Ahmadi, Ming, Yan, Andreas, Bauche, Ralf, Smeets, Christa E, Müller, Friedrich, Koch-Nolte, Friedrich, Haag, Ralf, Fliegert, Lan, Kluwe, Julian, Schulze Zur Wiesch, Philip, Hartjen
Publikováno v:
Cellular immunology. 380
The pulp of human teeth contains a population of self-renewing stem cells that can regulate the functions of immune cells. When applied to patients, these cells can protect tissues from damage by excessive inflammation. We confirm that dental pulp ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a002ea2f34d4c613d0a051bc44c1b0c1
https://pubmed.ncbi.nlm.nih.gov/36084401
https://pubmed.ncbi.nlm.nih.gov/36084401
Publikováno v:
Protein science : a publication of the Protein Society. 31(6)
Transient receptor potential melastatin 2 (TRPM2) is a Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da91cf9cff676333eb0b6355c7e8add7
https://pubmed.ncbi.nlm.nih.gov/35634784
https://pubmed.ncbi.nlm.nih.gov/35634784